Biological Science (6th Edition)
6th Edition
ISBN: 9780321976499
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Emily Taylor, Greg Podgorski, Jeff Carmichael
Publisher: PEARSON
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Chapter 9, Problem 15PIAT
Summary Introduction
To review:
The effect of DNP (2,4-dinitrophenol) on lowering the weight gain by comparing the treated and control group of mice.
Introduction:
The DNP is a drug which dissipates the proton gradient across the mitochondrial membrane, which collapses the proton-motive force (PMF). The PMF is used for the generation of ATP (adenosine triphosphate). The production of ROS can be reduced using drugs that allow protons to freely pass through the inner membrane. The effect of DNP on the life span of mice is shown in the graph below. Each point represents the death of a single mouse.
In this case, in addition to an increased life span, mice treated with low concentrations of DNP also showed a significantly lower weight gain compared to the control group despite no difference in the amount or type of food ingested.
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Chapter 9 Solutions
Biological Science (6th Edition)
Ch. 9 - Where does the citric acid cycle occur in...Ch. 9 - 2. What does the chemiosmotic hypothesis claim?
a....Ch. 9 - 3. After glucose is fully oxidized by glycolysis,...Ch. 9 - 4. What is the primary function of the reactions...Ch. 9 - Compare and contrast substrate-level...Ch. 9 - If you were to expose cells that are undergoing...Ch. 9 - In step 3 of the citric acid cycle, the enzyme...Ch. 9 - 8. Explain the relationship between electron...Ch. 9 - 9. Cyanide (C=N–) blocks complex IV of the...Ch. 9 - QUANTITATIVE Early estimates suggested that the...
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