ANAT.+PHYSIO.2-LAB.MAN. >CUSTOM<
20th Edition
ISBN: 9781264303090
Author: VanPutte
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Question
Chapter 9, Problem 11RAC
Summary Introduction
Introduction:
The neuromuscular junction is the region where motor neuron axon branches come in contact with the muscle fiber. Acetylcholinesterase is a molecule that prevents acetylcholine, a neurotransmitter, from getting accumulated within the synaptic cleft. This does not allow acetylcholine to act as a constant stimulus at the motor-endplate and thereby producing continuous muscle fiber contraction.
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If acetylcholinesterase fails to function properly at the neuromuscular junction, which of the following would be a consequence?
Death of the lower motor neuron
Saltatory conduction stops
Sodium channels do not open
Constant muscle cell contraction
hen an action potential arrives at the nerve terminal of a neuromuscular junction, which of the following statements best describes the events that occur?
Depolarisation of the nerve terminal causes the release of ACh which activates nicotinic receptors on the skeletal muscle membrane to cause Ca2+ entry and muscle contraction.
Depolarisation of the nerve terminal opens voltage-gated Ca2+ channels, Ca2+ entry brings vesicles containing ACh to the membrane which form fusion pores causing the release of ACh which activates voltage-gated Na+ channels at the end-plate.
Depolarisation of the nerve terminal opens voltage-gated Ca2+ channels, Ca2+ entry brings vesicles containing ACh to the membrane which form fusion pores causing the release of ACh which binds to muscarinic receptors at the end plate.
Depolarisation of the nerve terminal opens voltage-gated Ca2+ channels, Ca2+ entry brings vesicles containing ACh to the membrane which form fusion pores…
A motor unit associated with the stimulation of skeletal muscle is designated as a 1:8 motor unit. Which of the following statements is correct?
The motor unit consists of one somatic neuron and 8 myofibers (muscle fibers)
Each of the myofibers in the motor unit is innervated by more than one neuron
It is part of the autonomic nervous system
The neuron in the motor unit is an afferent neuron
Chapter 9 Solutions
ANAT.+PHYSIO.2-LAB.MAN. >CUSTOM<
Ch. 9.1 - List and describe the functions performed by...Ch. 9.1 - State the functions of smooth and cardiac muscle...Ch. 9.1 - Using table 9.1, distinguish among skeletal,...Ch. 9.2 - Identify the four specialized functional...Ch. 9.2 - Outline the differences in control and function...Ch. 9.3 - Name the connective tissue layers that surround...Ch. 9.3 - What are motor neurons? How do the axons of motor...Ch. 9.3 - What is the origin of muscle fibers? How do you...Ch. 9.3 - What are T tubules and the sarcoplasmic reticulum?Ch. 9.3 - Prob. 10AYP
Ch. 9.3 - Prob. 11AYPCh. 9.3 - Prob. 12AYPCh. 9.3 - Prob. 13AYPCh. 9.3 - Prob. 14AYPCh. 9.3 - Prob. 15AYPCh. 9.3 - Prob. 16AYPCh. 9.3 - Prob. 17AYPCh. 9.4 - What type of ion channel contributes to the...Ch. 9.4 - What are the two types of gated ion channels in...Ch. 9.4 - Prob. 20AYPCh. 9.4 - Prob. 21AYPCh. 9.4 - List the two types of voltage-gated channels the...Ch. 9.4 - Prob. 23AYPCh. 9.4 - Prob. 24AYPCh. 9.4 - Prob. 25AYPCh. 9.4 - Prob. 26AYPCh. 9.4 - Describe the structure of a neuromuscular...Ch. 9.4 - Prob. 28AYPCh. 9.4 - Prob. 29AYPCh. 9.4 - Prob. 30AYPCh. 9.4 - Prob. 31AYPCh. 9.4 - What ion is necessary for movement of the...Ch. 9.4 - Describe the steps in cross-bridge cycling. How is...Ch. 9.4 - Prob. 34AYPCh. 9.5 - List the phases of a muscle twitch, and describe...Ch. 9.5 - Prob. 36AYPCh. 9.5 - Prob. 37AYPCh. 9.5 - Prob. 38AYPCh. 9.5 - Prob. 39AYPCh. 9.5 - How does the lack of on unresponsive period in...Ch. 9.5 - Distinguish between active tension and passive...Ch. 9.5 - Prob. 42AYPCh. 9.5 - Prob. 43AYPCh. 9.5 - What is muscle tone, and how is it maintained?Ch. 9.6 - Contrast the structural and physiological...Ch. 9.6 - Prob. 46AYPCh. 9.6 - Prob. 47AYPCh. 9.6 - What factors contribute to increases in muscle...Ch. 9.6 - Prob. 49AYPCh. 9.6 - Prob. 50AYPCh. 9.7 - What is fatigue? List the three locations where...Ch. 9.7 - Prob. 52AYPCh. 9.7 - Prob. 53AYPCh. 9.7 - List the energy sources used to synthesize ATP for...Ch. 9.7 - Prob. 55AYPCh. 9.7 - Prob. 56AYPCh. 9.7 - Prob. 57AYPCh. 9.7 - Prob. 58AYPCh. 9.8 - Describe a typical smooth muscle cell. How do its...Ch. 9.8 - Prob. 60AYPCh. 9.8 - Prob. 61AYPCh. 9.8 - Compare visceral smooth muscle and multiunit...Ch. 9.8 - Prob. 63AYPCh. 9.8 - Prob. 64AYPCh. 9.8 - How are spontoneous contractions produced in...Ch. 9.8 - Prob. 66AYPCh. 9.8 - Prob. 67AYPCh. 9.8 - Prob. 68AYPCh. 9.9 - Prob. 69AYPCh. 9.9 - Prob. 70AYPCh. 9.10 - Prob. 71AYPCh. 9 - Which of these is true of skeletal muscle? a....Ch. 9 - Prob. 2RACCh. 9 - Prob. 3RACCh. 9 - Each myofibril Is made up of many muscle fibers....Ch. 9 - Prob. 5RACCh. 9 - Which of these statements about the molecular...Ch. 9 - Prob. 7RACCh. 9 - Prob. 8RACCh. 9 - Prob. 9RACCh. 9 - Prob. 10RACCh. 9 - Prob. 11RACCh. 9 - Prob. 12RACCh. 9 - Prob. 13RACCh. 9 - With stimuli of increasing strength, which of...Ch. 9 - Considering the force of contraction of a skeletal...Ch. 9 - Which of these events occurs during the lag...Ch. 9 - Prob. 17RACCh. 9 - Prob. 18RACCh. 9 - Given the conditions: (1) low ATP levels (2)...Ch. 9 - Prob. 20RACCh. 9 - Prob. 21RACCh. 9 - Prob. 22RACCh. 9 - Prob. 23RACCh. 9 - Prob. 24RACCh. 9 - Which of these statements concerning aging and...Ch. 9 - Prob. 1CTCh. 9 - A patient is thought to be suffering from either...Ch. 9 - Design an experiment to test the following...Ch. 9 - Explain what is happening at the level of...Ch. 9 - Predict the shape of an active tension curve for...Ch. 9 - Prob. 6CTCh. 9 - Prob. 7CTCh. 9 - Prob. 8CTCh. 9 - Prob. 9CTCh. 9 - Prob. 10CTCh. 9 - Prob. 11CTCh. 9 - Prob. 12CT
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- When an action potential arrives at the neuromuscular junction, acetylcholine is released into the synaptic cleft and binds to receptors in the postsynaptic membrane. Which of the following represents the correct order of the next series of events? A. An action potential travels down the T tubules, depolarization spreads through the T tubules, Ca2+ is released from the sarcoplasmic reticulum, and myosin binds to actin. B. Ca2+ is released from the sarcoplasmic reticulum, an action potential travels down the T tubules, depolarization spreads through the T tubules, and myosin binds to actin. C. An action potential travels down the T tubules, depolarization spreads through the T tubules, Ca2+ is taken up by the sarcoplasmic reticulum, and myosin binds to actin. D. T tubules are depolarized, Ca2+ is released from the sarcoplasmic reticulum, an action potential is created in the muscle cell, and myosin bonds to actin. E. An action potential travels…arrow_forwardWhat system will reset the membrane potential after an action potential has moved along the sarcolemma? acetylcholine receptors Na+-K+ pump desmosomes voltage-gated Ca2+ channelsarrow_forwardFrom the following choices, choose the THREE, that would result in prevention of muscle contraction (in other words, which three descriptive changes below would result in flaccid paralysis of a muscle). exocytosis of acetylcholine is constant, even without action potential injection of botulinum toxin calcium cannot be pumped back into the terminal cisternae acetylcholine receptor remains open to sodium active sites on actin a permanently exposed dramatically increase the activity of acetylcholinesterase calcium cannot bind troponinarrow_forward
- Put in order the steps of activation, excitation and contraction of skeletal muscle.arrow_forwardWhy does damage to upper motor neurons cause spasticity and muscle cramps? Extracellular calcium is decreased lower motor neurons are over excited Lengthens sarcomeres and thus increase tension Cause synaptic fatigue Neuromuscular junction is disruptedarrow_forwardBotulism is a disease that was associated to eating out of cans that had been contaminated by a deadly bacteria. It is an anaerobic bacteria (does not need oxygen to survive). What botulism does is It floods hte area with sodium O prevents the sarcoplasmic reticulum from releasing Calcium O prevent the release of the neurotransmitter acetylcholine prevent the release of the neurotransmitter dopaminearrow_forward
- Which of the following step(s) about the excitation of skeletal muscle is/are incorrect? 1. Acetylcholine is released and binds to motor end plate receptors 2. An action potential is created and moves down T-tubules 3. Calcium is released from the sarcoplasmic reticulum 4. Calcium ions bind to tropomyosin to shift troponin off the binding sites for cross-bridging 5. Myosin forms cross-bridges and binds with actin to pull it towards middle of sarcomerearrow_forwardCurare blocks acetylcholine receptors at the motor end plate. What would be the effect of this drug on muscle contraction? increased stimulation of the muscle. more acetylcholinesterase production. lack of Ca2+ uptake by the muscle fiber. inability of the muscle fiber to respond to nervous stimulation. sustained contraction of the muscle.arrow_forwardA motor unit consists of: Lower Motor Neuron cell body Axons O Muscle fibres All of the abovearrow_forward
- Which of the following correctly states the importance of an action potential to muscle contration? The SR will only release Ca2+ if it has been electrically stimulated. Sarcomeres require a negative electrical charge to start sliding. Actin and myosin must be electrically charged to create a cross-bridge. ATP cannot be split into ADP and Pi without an action potential.arrow_forwardInterruption of γ-motor neuron discharge to a skeletal muscle produces :-a- contraction of the muscleb- contraction of the spindle fibersc- relaxation of the spindle fibersd- increased sensory discharge from the spindle fibersarrow_forwardMuscle spindles are the sensory receptors that monitor the length of skeletal muscles. When the length of the hamstrings changes between standing and seated positions, which structure is responsible for adjusting the length of the intrafusal muscle fibers of the muscle spindle? Group of answer choices beta motor neurons gamma motor neurons extrafusal fibers alpha motor neuronsarrow_forward
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