Campbell Biology in Focus, Books a la Carte Edition; Modified Mastering Biology with Pearson eText - ValuePack Access Card - for Campbell Biology in Focus (2nd Edition)
2nd Edition
ISBN: 9780134433769
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Textbook Question
Chapter 9, Problem 10TYU
SYNTHESIZE YOUR KNOWLEDGE
Shown here are two He La cancer cells that are just completing cytokinesis. Explain how the cell division of cancer cells like these is misregulated. What genetic and other changes might have caused these cells to escape normal cell cycle regulation?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Just give the answers please
Cancer cells typically lose cell cycle entry control. Explain how the following mutations, which are found in some cancer cells, lead to a bypass of these controls: (a) overexpression of cyclin D, (b) loss of Rb function, (c) loss of p16 function, (d) hyperactive E2F.
Despite being small animals, naked mole rats are almost entirely resistant to cancer. Watch the following brief video on one potential mechanism for the prevention of cancer in naked mole rats.
https://youtu.be/bhNBeuhxkF0?si=38aelHLW1N6vN8-b
Based on what you know about mitosis and cancer cells, why would a mechanism that prevents cell crowding reduce the likelihood of cancer developing?
Chapter 9 Solutions
Campbell Biology in Focus, Books a la Carte Edition; Modified Mastering Biology with Pearson eText - ValuePack Access Card - for Campbell Biology in Focus (2nd Edition)
Ch. 9.1 - WHAT IF? A chicken has 78 chromosomes in its...Ch. 9.2 - Compare cytokinesis in animal cells and plant...Ch. 9.2 - Prob. 3CCCh. 9.2 - Compare the roles of tubulin and actin during...Ch. 9.3 - Prob. 1CCCh. 9.3 - Prob. 2CCCh. 9.3 - Compare and contrast a benign tumor and a...Ch. 9.3 - Prob. 4CCCh. 9 - Through a microscope, you can see a cell plate...Ch. 9 - In the cells of some organisms, mitosis occurs...
Ch. 9 - Which of the following does not occur during...Ch. 9 - Prob. 4TYUCh. 9 - The drug cytochalasin B blocks the function of...Ch. 9 - DRAW IT Draw one eukaryotic chromosome as it would...Ch. 9 - The light micrograph shows dividing cells near the...Ch. 9 - SCIENTIFIC INQUIRY Although both ends of a...Ch. 9 - FOCUS ON EVOLUTION The result of mitosis is that...Ch. 9 - SYNTHESIZE YOUR KNOWLEDGE Shown here are two He La...Ch. 9 - FOCUS ON INFORMATION The continuity of life is...
Additional Science Textbook Solutions
Find more solutions based on key concepts
6. How can you use the features found in each chapter?
Human Anatomy & Physiology (2nd Edition)
More than one choice may apply. Using the terms listed below, fill in the blank with the proper term. anterior ...
Essentials of Human Anatomy & Physiology (12th Edition)
To test your knowledge, discuss the following topics with a study partner or in writing ideally from memory. Th...
Human Anatomy
Describe the role and impact of microbes on the earth.
Microbiology Fundamentals: A Clinical Approach - Standalone book
Some species of bacteria that live at the surface of sediment on the bottom of lakes are capable of using eithe...
Biology: Life on Earth with Physiology (11th Edition)
Consider the experiment described in Section 2.1 in which Ted Garland and colleagues bred mice to run long dist...
Evolutionary Analysis (5th Edition)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- I need help woth this question pleasearrow_forwardFigure 28.11 depicts the eukaryotic cell cycle. Many cell types “exit� the cell cycle and don’t divide for prolonged periods, a state termedG0; some, for example neurons, never divide again. a. In what stage of the cell cycle do you suppose a cell might be when it exits the cell cycle and enters G0? b. The cell cycle is controlled by checkpoints, cyclins, and CDKs. Describe how biochemical events involving cyclins and CDKs might control passage of a dividing cell through the cell cycle.arrow_forwardFigure 10.13 Rb and other proteins that negatively regulate the cell cycle are sometimes called tumor suppressors. Why do you think the name tumor suppressor might be appropriate for these proteins?arrow_forward
- Choose one of these answersarrow_forwardArtificially induced apoptosis (controlled cellular death) is found to be an effective treat- ment for some forms of cancer. Which of the following describes the most likely mechanism by which apoptosis might be induced? A B с D by causing ribosomes to increase the rate of protein synthesis by triggering the division of mitochondria in the cell to increase ATP production by increasing the expression of membrane-bound glucose protein channels by causing lysosomes to release digestive enzymes into the cytosolarrow_forwardDiscuss the complete cell cycle in a human cell, mitosis and meiosis, and the regulatory components (i.e. the proteins associated with cellular checkpoints) of the cell cycle. Tumor growth results when the cell cycle checkpoints are ignored. Give an example of how tumor growth could result from either a loss-of-function or a gain-of-function mutation.arrow_forward
- Briefly describe the cell cycle, its checkpoints, and the general proteins required to move past each checkpoint. For each cell cycle checkpoint, be sure to describe what the cell is "checking for" and how this "check" occurs, along with the result if the checkpoint cannot be passed. Your answer should also include a description of the structure of MPF, its regulation, and its general targets or functions. Be sure to include any accessory molecules or proteins involved in regulation of MPF, while also describing the process by which MPF is formed and activated. In this answer, you should also choose two proteins involved in the cell cycle, which, if mutated, will cause cancer. Describe these proteins and their normal functions, and then show how a mutation in these proteins will result in cancer.arrow_forwardWhat role do aurora kinase play in the cell cycle and how would using these kinases as target for cancer treated work?arrow_forwardIn your own words, explain how cancer cells differ from normal cells in regard to the following: Molecular controls of the cell cycle (include Cdk and Cdk/cyclin complexes, p53 gene/protein, Rb gene/protein in response)arrow_forward
- Shown here are two HeLa cancer cells that are just completing cytokinesis. Explain how the cell division of cancer cellslike these is misregulated. Identify genetic and other changesthat might have caused these cells to escape normal cell cycleregulationarrow_forwardlook at the screenshot pleasearrow_forwardBy what molecular pathway does loss of cell cycle regulation in an organism lead to cancer? What genetic changes can cooperate to accomplish the cancer cell’s escape from the normal balance of cell growth?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Biology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage LearningBiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
cell division of meiosis and mitosis; Author: Stated Clearly;https://www.youtube.com/watch?v=A-mFPZLLbHI;License: Standard youtube license