Bundle: Chemistry for Today: General, Organic, and Biochemistry, Loose-Leaf Version, 9th + LMS Integrated OWLv2, 4 terms (24 months) Printed Access Card
9th Edition
ISBN: 9781337598255
Author: Spencer L. Seager
Publisher: Cengage Learning
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Chapter 8, Problem 8.32E
A reaction is run at
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need help please and thanks dont understand only need help with C-F
Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal…
Please correct answer and don't used hand raiting
need help please and thanks dont understand a-b
Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal energy
Divide the…
Chapter 8 Solutions
Bundle: Chemistry for Today: General, Organic, and Biochemistry, Loose-Leaf Version, 9th + LMS Integrated OWLv2, 4 terms (24 months) Printed Access Card
Ch. 8 - Classify the following processes as spontaneous or...Ch. 8 - Classify the following processes as spontaneous or...Ch. 8 - Classify the following processes as exergonic or...Ch. 8 - Classify the following processes as exergonic or...Ch. 8 - Describe the energy and entropy changes that occur...Ch. 8 - Describe the energy and entropy changes that occur...Ch. 8 - Pick the example with the highest entropy from...Ch. 8 - Pick the example with the highest entropy from...Ch. 8 - You probably know that on exposure to air silver...Ch. 8 - Classify the following processes according to...
Ch. 8 - Classify the following processes according to...Ch. 8 - Describe the observations or measurements that...Ch. 8 - Prob. 8.13ECh. 8 - Consider the following hypothetical reaction: A+BC...Ch. 8 - Consider the following hypothetical reaction: A+BC...Ch. 8 - A reaction generates chlorine gas (Cl2) as a...Ch. 8 - A reaction generates hydrogen gas (H2) as a...Ch. 8 - Prob. 8.18ECh. 8 - Prob. 8.19ECh. 8 - In each of the following, which reaction mechanism...Ch. 8 - Which reaction mechanism assumptions are...Ch. 8 - Prob. 8.22ECh. 8 - Sketch energy diagrams to represent each of the...Ch. 8 - Prob. 8.24ECh. 8 - Use energy diagrams to compare catalyzed and...Ch. 8 - Prob. 8.26ECh. 8 - The following reactions are proposed. Make a rough...Ch. 8 - Prob. 8.28ECh. 8 - Prob. 8.29ECh. 8 - Suppose you are running a reaction and you want to...Ch. 8 - A reaction is started by mixing reactants. As time...Ch. 8 - A reaction is run at 10C and takes 3.7hours to go...Ch. 8 - What factor is more important than simply the...Ch. 8 - Prob. 8.34ECh. 8 - Describe the establishment of equilibrium in a...Ch. 8 - Prob. 8.36ECh. 8 - Prob. 8.37ECh. 8 - Colorless hydrogen gas (H2) and red-brown colored...Ch. 8 - Colorless N2O4 gas decomposes to form red-brown...Ch. 8 - Prob. 8.40ECh. 8 - Write an equilibrium expression for each of the...Ch. 8 - Prob. 8.42ECh. 8 - Prob. 8.43ECh. 8 - Prob. 8.44ECh. 8 - Prob. 8.45ECh. 8 - A sample of gaseous BrCl is allowed to decompose...Ch. 8 - At 600C, gaseous CO and Cl2 are mixed together in...Ch. 8 - A mixture of the gases NOCl, Cl2 and NO is allowed...Ch. 8 - Consider the following equilibrium constants....Ch. 8 - Prob. 8.50ECh. 8 - Use Le Chteliers principle to predict the...Ch. 8 - Use Le Chteliers principle to predict the...Ch. 8 - Use Le Chteliers principle to predict the...Ch. 8 - Prob. 8.54ECh. 8 - Tell what will happen to each equilibrium...Ch. 8 - Tell what will happen to each equilibrium...Ch. 8 - The gaseous reaction 2HBr(g)H2(g)+Br2(g) is...Ch. 8 - Prob. 8.58ECh. 8 - Prob. 8.59ECh. 8 - Prob. 8.60ECh. 8 - Prob. 8.61ECh. 8 - Prob. 8.62ECh. 8 - Prob. 8.63ECh. 8 - Prob. 8.64ECh. 8 - Prob. 8.65ECh. 8 - Prob. 8.66ECh. 8 - Refer to Figure 8.10 and answer the questions....Ch. 8 - Refer to Figure 8.13 and answer the questions....Ch. 8 - Prob. 8.69ECh. 8 - Prob. 8.70ECh. 8 - Suppose you have two identical unopened bottles of...Ch. 8 - Someone once suggested that it is impossible to...Ch. 8 - A reaction takes place between an acid and...Ch. 8 - If the reaction:A+BC+D is designated as first...Ch. 8 - Prob. 8.75ECh. 8 - A book is held 6 feet above the floor and then...Ch. 8 - Prob. 8.77ECh. 8 - Prob. 8.78ECh. 8 - Prob. 8.79ECh. 8 - Prob. 8.80ECh. 8 - Prob. 8.81ECh. 8 - Which of the following is the best example of...Ch. 8 - Which is NOT an example of an endothermic change?...Ch. 8 - Which of the following processes is endothermic?...Ch. 8 - Which sentence best describes the following...Ch. 8 - By which of the following mechanisms does a...Ch. 8 - Which of the following is NOT true of reversible...Ch. 8 - Given the reaction: 2CO(g)+O2(g)2CO2(g) When there...Ch. 8 - Prob. 8.89ECh. 8 - Consider the reaction N2(g)+3H2(g)2NH3(g)+heat....Ch. 8 - Prob. 8.91ECh. 8 - Prob. 8.92ECh. 8 - For the reaction: H2(g)+Br2(g)2HBr(g), the...Ch. 8 - Prob. 8.94E
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