Human Biology: Concepts and Current Issues Plus Mastering Biology with Pearson eText -- Access Card Package (8th Edition)
8th Edition
ISBN: 9780134042237
Author: Michael D. Johnson
Publisher: PEARSON
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Chapter 8, Problem 3CR
Summary Introduction
To review:
Measurement of arterial blood pressure by the body.
Introduction:
The force that is exerted by the blood on the walls of the vessel is known as blood pressure. This pressure is not same in all blood vessels and also in a person, it varies but is always within a range consistent with being able to provide blood to all cells. Normally, blood pressure is regulated within very narrow limits by a negative feedback control loop, which is governed by baroreceptors present in several of the large arteries including the aorta and the two carotid arteries.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 8 Solutions
Human Biology: Concepts and Current Issues Plus Mastering Biology with Pearson eText -- Access Card Package (8th Edition)
Ch. 8 -
1. Who do you want to help you decide which...Ch. 8 - Do you think cost-effectiveness should be a part...Ch. 8 -
1. Why is it so important that the heart always...Ch. 8 - Compare and contrast the structures and functions...Ch. 8 - Prob. 3CRCh. 8 - Describe the function of the heart valves.Ch. 8 - Compare the functions of the pulmonary circuit and...Ch. 8 -
6. Describe the cardiac cycle of relaxation and...Ch. 8 - Describe the function of the SA and AV nodes as...Ch. 8 - Prob. 8CR
Ch. 8 - Prob. 9CRCh. 8 - Prob. 10CRCh. 8 -
1. _______ carry blood away from the heart and...Ch. 8 - Prob. 2TYCh. 8 - Which of the choices represents the order of...Ch. 8 - Prob. 4TYCh. 8 - Prob. 5TYCh. 8 - Prob. 6TYCh. 8 - Prob. 7TYCh. 8 - A pacemaker is used to correct: a. coronary artery...Ch. 8 - Prob. 9TYCh. 8 - Prob. 10TYCh. 8 - Prob. 11TYCh. 8 - Prob. 12TYCh. 8 - Prob. 13TYCh. 8 - Prob. 14TYCh. 8 - Prob. 15TYCh. 8 - Prob. 1AWKCh. 8 - When a coronary artery bypass graft (CABG) is...Ch. 8 - Soldiers have to stand in formation at full...Ch. 8 - Prob. 4AWKCh. 8 - Prob. 5AWKCh. 8 - Ventricular fibrillation is a potentially fatal...Ch. 8 - Prob. 7AWKCh. 8 - Last night, you and your roommate were sound...
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