To examine: Whether the statement, “Because a monoclonal antibody recognizes a specific antigenic site (epitope), it binds only to the specific protein against which it was made.” is true or false. Concept introduction: Monoclonal antibodies are the protein molecules, which developed in laboratory condition that particularly binds with the target antigens. Monoclonal antibodies are designed by the fusion of spleen cells that are modified with desired antigens and myeloma cells.

Question

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Answer 1

Question

Chapter 8, Problem 1P

Summary Introduction

To examine: Whether the statement, “Because a monoclonal antibody recognizes a specific antigenic site (epitope), it binds only to the specific protein against which it was made.” is true or false.

Concept introduction:

Monoclonal antibodies are the protein molecules, which developed in laboratory condition that particularly binds with the target antigens. Monoclonal antibodies are designed by the fusion of spleen cells that are modified with desired antigens and myeloma cells.

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

Monoclonal antibodies have the capacity to recognize the specialized antigenic site, but it is not specific for a particular protein molecule. However, same antibody attaches with various antigens having antigenic similarities with different affinities. If in an assay, there are utilization of excess amount of antibody occurs, binding affinities of that specific antibody may differ according to the antigen. There are some proteins, which attaches to antibody with high affinity and others with less affinity.

Hence, the statement is false.

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Question #3: In the KeyGene paper, the authors state that it would be useful if pollen from an apomict would transmit apomixis-inducing genes to the female in the cross (assuming the pollen is viable). Assuming there was just one gene conferring gametophytic obligate apomixis, and that the two parents are inbreds, what would be the consequences of such a cross if: a) The apomixis was a dominant trait? Indicate the genotypes and phenotypes (apomict or non- apomict) of the parents, F1 and F2 generations. Remember to include the expected genotypic and phenotypic ratios (or percentages) in the F1 and F2 generations, and to position the female first (left side) in the parental cross. b) The apomixis was a recessive trait? Indicate the genotypes and phenotypes (apomict or non- apomict) of the parents, F1 and F2 generations. Remember to include the expected genotypic and phenotypic ratios (or percentages) in the F1 and F2 generations, and to position the female first (left side) in the…

Answer 2

Question

Chapter 8, Problem 1P

Summary Introduction

To examine: Whether the statement, “Because a monoclonal antibody recognizes a specific antigenic site (epitope), it binds only to the specific protein against which it was made.” is true or false.

Concept introduction:

Monoclonal antibodies are the protein molecules, which developed in laboratory condition that particularly binds with the target antigens. Monoclonal antibodies are designed by the fusion of spleen cells that are modified with desired antigens and myeloma cells.

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

Monoclonal antibodies have the capacity to recognize the specialized antigenic site, but it is not specific for a particular protein molecule. However, same antibody attaches with various antigens having antigenic similarities with different affinities. If in an assay, there are utilization of excess amount of antibody occurs, binding affinities of that specific antibody may differ according to the antigen. There are some proteins, which attaches to antibody with high affinity and others with less affinity.

Hence, the statement is false.

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Answer 3

Question

Chapter 8, Problem 1P

Summary Introduction

To examine: Whether the statement, “Because a monoclonal antibody recognizes a specific antigenic site (epitope), it binds only to the specific protein against which it was made.” is true or false.

Concept introduction:

Monoclonal antibodies are the protein molecules, which developed in laboratory condition that particularly binds with the target antigens. Monoclonal antibodies are designed by the fusion of spleen cells that are modified with desired antigens and myeloma cells.

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

Monoclonal antibodies have the capacity to recognize the specialized antigenic site, but it is not specific for a particular protein molecule. However, same antibody attaches with various antigens having antigenic similarities with different affinities. If in an assay, there are utilization of excess amount of antibody occurs, binding affinities of that specific antibody may differ according to the antigen. There are some proteins, which attaches to antibody with high affinity and others with less affinity.

Hence, the statement is false.

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Answer 4

Question

Chapter 8, Problem 1P

Summary Introduction

To examine: Whether the statement, “Because a monoclonal antibody recognizes a specific antigenic site (epitope), it binds only to the specific protein against which it was made.” is true or false.

Concept introduction:

Monoclonal antibodies are the protein molecules, which developed in laboratory condition that particularly binds with the target antigens. Monoclonal antibodies are designed by the fusion of spleen cells that are modified with desired antigens and myeloma cells.

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

Monoclonal antibodies have the capacity to recognize the specialized antigenic site, but it is not specific for a particular protein molecule. However, same antibody attaches with various antigens having antigenic similarities with different affinities. If in an assay, there are utilization of excess amount of antibody occurs, binding affinities of that specific antibody may differ according to the antigen. There are some proteins, which attaches to antibody with high affinity and others with less affinity.

Hence, the statement is false.

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Answer 5

Chapter 8, Problem 1P

Summary Introduction

To examine: Whether the statement, “Because a monoclonal antibody recognizes a specific antigenic site (epitope), it binds only to the specific protein against which it was made.” is true or false.

Concept introduction:

Monoclonal antibodies are the protein molecules, which developed in laboratory condition that particularly binds with the target antigens. Monoclonal antibodies are designed by the fusion of spleen cells that are modified with desired antigens and myeloma cells.

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

Monoclonal antibodies have the capacity to recognize the specialized antigenic site, but it is not specific for a particular protein molecule. However, same antibody attaches with various antigens having antigenic similarities with different affinities. If in an assay, there are utilization of excess amount of antibody occurs, binding affinities of that specific antibody may differ according to the antigen. There are some proteins, which attaches to antibody with high affinity and others with less affinity.

Hence, the statement is false.

Answer 6

Chapter 8, Problem 1P

Summary Introduction

To examine: Whether the statement, “Because a monoclonal antibody recognizes a specific antigenic site (epitope), it binds only to the specific protein against which it was made.” is true or false.

Concept introduction:

Monoclonal antibodies are the protein molecules, which developed in laboratory condition that particularly binds with the target antigens. Monoclonal antibodies are designed by the fusion of spleen cells that are modified with desired antigens and myeloma cells.

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

Monoclonal antibodies have the capacity to recognize the specialized antigenic site, but it is not specific for a particular protein molecule. However, same antibody attaches with various antigens having antigenic similarities with different affinities. If in an assay, there are utilization of excess amount of antibody occurs, binding affinities of that specific antibody may differ according to the antigen. There are some proteins, which attaches to antibody with high affinity and others with less affinity.

Hence, the statement is false.

Answer 7

Chapter 8, Problem 1P

Summary Introduction

To examine: Whether the statement, “Because a monoclonal antibody recognizes a specific antigenic site (epitope), it binds only to the specific protein against which it was made.” is true or false.

Concept introduction:

Monoclonal antibodies are the protein molecules, which developed in laboratory condition that particularly binds with the target antigens. Monoclonal antibodies are designed by the fusion of spleen cells that are modified with desired antigens and myeloma cells.

Answer 8

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Explanation of Solution

Monoclonal antibodies have the capacity to recognize the specialized antigenic site, but it is not specific for a particular protein molecule. However, same antibody attaches with various antigens having antigenic similarities with different affinities. If in an assay, there are utilization of excess amount of antibody occurs, binding affinities of that specific antibody may differ according to the antigen. There are some proteins, which attaches to antibody with high affinity and others with less affinity.

Hence, the statement is false.

Answer 12

Ch. 8 - Prob. 1P Ch. 8 - Prob. 2P Ch. 8 - Prob. 3P Ch. 8 - Prob. 4P Ch. 8 - Prob. 5P Ch. 8 - Prob. 6P Ch. 8 - Prob. 7P Ch. 8 - Prob. 8P Ch. 8 - Prob. 9P Ch. 8 - Prob. 10P

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