Biology: Science for Life with Physiology (5th Edition)
5th Edition
ISBN: 9780321922212
Author: Colleen Belk, Virginia Borden Maier
Publisher: PEARSON
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Chapter 8, Problem 11LTB
Summary Introduction
Introduction:
The quantitative traits are the measurable
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When a disease is due to polygenic inheritance, the following is probably true:
A. Many factors, both genetic and environmental, contribute to the disease traits.
B. It is caused by one gene with a large number of alleles.
C. It affects a large number of people.
D. It has many different symptoms
Parents often want to know what is genetically possible for their children. If two parents are
carriers for a recessive lethal trait, what are the odds that their child is also a carrier?
Many times there is interest in tracking multiple traits at once (not just 1 or 2). The same
probability rules apply here, you just multiple all the odds together at once. Imagine two
parents. They are both carriers for red hair, one person is blood type AB, the other is type O.
They want to know the odds of a daughter with red hair and type B blood. Please do no not do
a giant Punnett square! Use probability or individual squares.
a. What are the genotypes of the parents?
b. What are the odds of each trait (daughter, red hair, type B)
If a genetic disease is inherited on the basis of an autosomal dominant gene, one would expect
to find which of the following?
A. Affected fathers have only affected children.
B. Affected mothers never have affected sons.
C. If both parents are affected, all of their offspring have the disease.
D. If a child has the disease, one of his or her grandparents also had the disease.
Chapter 8 Solutions
Biology: Science for Life with Physiology (5th Edition)
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- Many genetic disorders are inherited in a recessive manner Select one: a. False b. Truearrow_forwardThe difference between dominant and recessive traits is … Group of answer choices: A.genes for dominant traits are passed on preferentially. B.effects of recessive traits can be hidden by effects of dominant traits. C.recessive traits are deleterious (bad for the organism) and dominant traits are not. D.dominant genes produce proteins, recessive genes do not. E.dominant traits are more likely to be expressed in males.arrow_forwardPedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?arrow_forward
- Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you want to know the results of the cancer, heart disease, and TSD tests if you were Sarah and Adam? Is it their responsibility as potential parents to gather this type of information before they decide to have a child?arrow_forwardPedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you decide to have a child if the test results said that you carry the mutation for breast and ovarian cancer? The heart disease mutation? The TSD mutation? The heart disease and the mutant alleles?arrow_forwardPedigree Analysis Is a Basic Method in Human Genetics Pedigree analysis permits all of the following except: a. an orderly presentation of family information b. the determination of whether a trait is genetic c. the determination of whether a trait is dominant or recessive d. an understanding of which gene is involved in a heritable disorder e. the determination of whether a trait is sex-linked or autosomalarrow_forward
- An individual who is a carrier for a sex-linked trait such as hemophilia Select one: A. is always female. B. is homozygous for the recessive condition. C. cannot pass the gene on to his or her daughters. D. shows the dominant phenotype.arrow_forwardWill insurance companies be able to deny coverage or even treatment of illnesses that can now be revealed through in utero genetic testing?arrow_forwardBiological determinism is the idea that most human characteristics, physical and mental, are determined at conception by hereditary factors passed from parent to offspring. However, this approach is considered limiting. Why is that?arrow_forward
- In the future, gene technology may make it possible for parents to produce children with athletic ability, artistic talent, or high IQ. Do you have any ethical concerns about these possibilities? If so, where and how would you draw the line?arrow_forwardPhenotype is the allele combinations of an individual that cause traits or diseases. Genotype is the expression of a gene in traits or symptoms. A. Both statements are correct B. Both statements are incorrect C. First statement is Correct, Second is Incorrect D. First statement is Incorrect, Second is Correctarrow_forwardThe two genes are, the likely they are to be inherited together. A. farther, more B. more, more C. closer, less D. closer, morearrow_forward
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