The role of the skeleton as a calcium reservoir in regulating blood calcium levels. Introduction: Mineralization is a process (crystallization) that deposit phosphate, calcium, and other ions (from blood plasma) in the tissues of the bone as hydroxyapatite. This process is initiated by the osteoblast by laying collagen fibers on the surface of the osteon. These fibers are coated with minerals that make the matrix hard. Only if the concentration of the products (of above minerals) in the plasma reaches the critical value (solubility product), the hydroxyapatite is formed. Sometimes, calcification is repressed by some inhibitors found in the tissue. These inhibitors are deactivated by osteoblast and it enables the precipitation of the salt in the matrix of the bone. The initially formed crystals perform like a “seed of crystals” and it attracts more phosphate and calcium from the plasma.

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Chapter 7.4, Problem 4AYLO

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The role of the skeleton as a calcium reservoir in regulating blood calcium levels.

Introduction:

Mineralization is a process (crystallization) that deposit phosphate, calcium, and other ions (from blood plasma) in the tissues of the bone as hydroxyapatite. This process is initiated by the osteoblast by laying collagen fibers on the surface of the osteon. These fibers are coated with minerals that make the matrix hard. Only if the concentration of the products (of above minerals) in the plasma reaches the critical value (solubility product), the hydroxyapatite is formed. Sometimes, calcification is repressed by some inhibitors found in the tissue. These inhibitors are deactivated by osteoblast and it enables the precipitation of the salt in the matrix of the bone. The initially formed crystals perform like a “seed of crystals” and it attracts more phosphate and calcium from the plasma.

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