Anatomy & Physiology: The Unity of Form and Function (Standalone Book)
7th Edition
ISBN: 9780073403717
Author: Kenneth S. Saladin Dr.
Publisher: McGraw-Hill Education
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Chapter 7, Problem 18TYR
Summary Introduction
Introduction:
The common bone disease occurs due to very low bone density that makes the bone brittle and frequent physiological pathological fractures for mild stress. This mechanism can be disrupted in many ways like a birth defect, genetic abnormality and developmental delay which causes debilitation physically and mentally.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 7 Solutions
Anatomy & Physiology: The Unity of Form and Function (Standalone Book)
Ch. 7.1 - Prob. 1BYGOCh. 7.1 - Prob. 2BYGOCh. 7.1 - Prob. 3BYGOCh. 7.1 - Prob. 4BYGOCh. 7.1 - Prob. 5BYGOCh. 7.1 - Prob. 1AYLOCh. 7.1 - Prob. 2AYLOCh. 7.1 - Prob. 3AYLOCh. 7.1 - Prob. 4AYLOCh. 7.1 - Prob. 5AYLO
Ch. 7.1 - Prob. 6AYLOCh. 7.1 - Prob. 7AYLOCh. 7.1 - Prob. 8AYLOCh. 7.2 - Prob. 6BYGOCh. 7.2 - Prob. 7BYGOCh. 7.2 - Prob. 8BYGOCh. 7.2 - Prob. 9BYGOCh. 7.2 - Prob. 10BYGOCh. 7.2 - Prob. 1AYLOCh. 7.2 - Prob. 2AYLOCh. 7.2 - Prob. 3AYLOCh. 7.2 - Prob. 4AYLOCh. 7.2 - Prob. 5AYLOCh. 7.2 - Prob. 6AYLOCh. 7.3 - Prob. 11BYGOCh. 7.3 - Prob. 12BYGOCh. 7.3 - Prob. 13BYGOCh. 7.3 - Prob. 14BYGOCh. 7.3 - Prob. 1AYLOCh. 7.3 - Prob. 2AYLOCh. 7.3 - Prob. 3AYLOCh. 7.3 - Prob. 4AYLOCh. 7.4 - Prob. 15BYGOCh. 7.4 - Prob. 16BYGOCh. 7.4 - Prob. 17BYGOCh. 7.4 - Prob. 18BYGOCh. 7.4 - Prob. 1AYLOCh. 7.4 - Prob. 2AYLOCh. 7.4 - Prob. 3AYLOCh. 7.4 - Prob. 4AYLOCh. 7.4 - Prob. 5AYLOCh. 7.4 - Prob. 6AYLOCh. 7.4 - Prob. 7AYLOCh. 7.4 - Prob. 8AYLOCh. 7.4 - Prob. 9AYLOCh. 7.4 - Prob. 10AYLOCh. 7.5 - Prob. 19BYGOCh. 7.5 - Prob. 20BYGOCh. 7.5 - Prob. 21BYGOCh. 7.5 - Prob. 1AYLOCh. 7.5 - Prob. 2AYLOCh. 7 - Which cells have a ruffled border and secrete...Ch. 7 - Prob. 2TYRCh. 7 - Prob. 3TYRCh. 7 - Osteoclasts are most closely related, by common...Ch. 7 - The walls between cartilage lacunae break down in...Ch. 7 - Which of these is not an effect of PTH? a. rise in...Ch. 7 - Prob. 7TYRCh. 7 - One long bone meets another at its a. diaphysis....Ch. 7 - Calcitriol is made from a. calcitonin. b....Ch. 7 - Prob. 10TYRCh. 7 - Calcium phosphate crystallizes in bone as a...Ch. 7 - Prob. 12TYRCh. 7 - Prob. 13TYRCh. 7 - Prob. 14TYRCh. 7 - Prob. 15TYRCh. 7 - Prob. 16TYRCh. 7 - Prob. 17TYRCh. 7 - Prob. 18TYRCh. 7 - Prob. 19TYRCh. 7 - Prob. 20TYRCh. 7 - Prob. 1BYMVCh. 7 - Prob. 2BYMVCh. 7 - Prob. 3BYMVCh. 7 - Prob. 4BYMVCh. 7 - ortho-Ch. 7 - Prob. 6BYMVCh. 7 - Prob. 7BYMVCh. 7 - Prob. 8BYMVCh. 7 - spic-Ch. 7 - topo-Ch. 7 - Prob. 1TFCh. 7 - Prob. 2TFCh. 7 - Prob. 3TFCh. 7 - The growth zone of the lone bones of adolescents...Ch. 7 - Prob. 5TFCh. 7 - Prob. 6TFCh. 7 - Whats Wrong with These Statements? 7. The protein...Ch. 7 - Prob. 8TFCh. 7 - Prob. 9TFCh. 7 - Prob. 10TFCh. 7 - Most osteocytes of an osteon are far removed from...Ch. 7 - Prob. 2TYCCh. 7 - How does the regulation of blood calcium...Ch. 7 - Describe how the arrangement of trabeculae in...Ch. 7 - Identify two bone diseases you would expect to see...
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