Campbell Biology in Focus
3rd Edition
ISBN: 9780134710679
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Rebecca Orr
Publisher: PEARSON
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Chapter 7.3, Problem 1CC
Name the molecules that conserve most of the energy from
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What is the citric acid cycle? Provide a schematic diagram of the citric acid cycle with chemical structures of each compound in the cycle. Indicate the cofactors and products at each step as well as the name of each of the enzymes involved.
What is the significance of substrate-level phosphorylation reactions? Which of the reactions in the citric acid cycle involve a substrate-level phosphorylation? Name another example from a biochemical pathway with which you are familiar.
match the cofactor with its function in the citric acid cycle by entering the number corresponding with the function. A given function may be used more than one time or not at all.
Use from the following list of functions to fill in the table below:
carries O2
carries small carbon-containing molecules
carries e-
carries small nitrogen-containing molecules
Cofactor
Function
NAD+/NADH
FAD/FADH2
CoA
thiamine
biotin
Chapter 7 Solutions
Campbell Biology in Focus
Ch. 7.1 - Compare and contrast aerobic and anaerobic...Ch. 7.1 - Name and describe the two ways in which ATP is...Ch. 7.1 - Prob. 3CCCh. 7.2 - During step 6 in Figure 7.9, which molecule acts...Ch. 7.3 - Name the molecules that conserve most of the...Ch. 7.3 - Prob. 2CCCh. 7.4 - Prob. 1CCCh. 7.4 - Prob. 2CCCh. 7.4 - MAKE CONNECTIONS Membranes must be fluid to...Ch. 7.5 - Prob. 1CC
Ch. 7.5 - WHAT IF? A glucose-fed yeast cell is moved from an...Ch. 7.6 - MAKE CONNECTIONS Compare the structure of a fat...Ch. 7.6 - Prob. 2CCCh. 7.6 - WHAT IF? During intense exercise, can a muscle...Ch. 7 - The immediate energy source that drives ATP...Ch. 7 - Which metabolic pathway is common to both...Ch. 7 - In mitochondria, exergonic redox reactions A. are...Ch. 7 - The final electron acceptor of the electron...Ch. 7 - What is the oxidizing agent in the following...Ch. 7 - When electrons flow along the electron transport...Ch. 7 - Most co, from catabolism is released during A....Ch. 7 - DRAW IT The graph here shows the pH difference...Ch. 7 - INTERPRET THE DATA Phosphofructokinase is an...Ch. 7 - Prob. 10TYUCh. 7 - FOCUS ON EVOLUTION ATP synthases are found in the...Ch. 7 - Prob. 12TYUCh. 7 - Prob. 13TYU
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- What enzymes from the citric acid cycle that are allosterically regulated by ATP and/or NADH? What enzymes from the citric acid cycle that allosterically regulated by NAD+?arrow_forwardWhat substance acts as the starting point of the citric acid cycle, reacting with acetyl-CoA in the first step and being regenerated in the last step? Draw its structure.arrow_forwardHow many NADH and how many FADH2 molecules are formed in the citric acid cycle?arrow_forward
- Since no molecular oxygen participates in the citric acid cycle, the steps in which acetyl groups are oxidized to CO2 involve removal of hydride ions and hydrogen ions. What is the acceptor of hydride ions? What is the acceptor of hydrogen ions?arrow_forward|a) Explain why the citric acid cycle is considered to be the center of cellular metabolism. b) What are the substrates and products corresponding to one turn of the citric acid cycle? (no need for enzymes) c) Which steps of the citric acid cycle release CO2 as a product? Which steps produce NADH or FADH2? Which step produces GTP? d) How much ATP can be generated from glucose when the citric acid cycle is operating?arrow_forwardWhat is the net reaction of the citric acid cycle? What happens to each product? OXIDATIVE PHOSPHORYLATION: 3A) Thoroughly explain the biological significance of NADH/H* and FADH₂ and their roles in oxidative phosphorylation. 3B) Describe and diagram the general pathway of the electrons from NADH/H+ and FADH2 to 02 during the electron transport chain. 3C) What is "chemiosmotic coupling", and what is its relationship to ATP synthesis? 3D) During oxidative phosphorylation, what is oxidized and what is phosphorylated?arrow_forward
- a) Describe the three irreversible reactions of the Citric Acid Cycle. Ensure to indicate their purpose/role, the substrates and products, the enzyme involved, and any significant features of the reaction. b) Why are these reactions considered irreversible (why can't they be reversed)? c) Using one of the reactions as an example, explain why it is important for the cell that the reaction is irreversible.arrow_forwardThere are eight chemical reactions that occur in the citric acid cycle process. The reactions of the citric acid cycle are shown in the figure below. acetyl-coenzyme A 0 CH₂-C-CoA HO-CH Reaction 7 O malate CH₂ CH || CH fumarate FADH₂ Reaction 6 FAD H+ + NADH NAD+ 1,0 H₂C CH₂ CH₂ Reaction 8 succinate ADP 0=C GTP CH₂ oxaloacetate Reaction 5 H-COA GDP ATP H₂O Reaction 1 C Reactions of the Citric Acid Cycle CH₂ CH₂ H-COA 0=C 1 CoA succinyl-CoA H+ HO-C Reaction CO₂ с CH₂ NADH CH₂ citrate Reaction 2 H-COA Reaction 3 CO₂ I CH₂ T CH₂ 0=C NAD+ HO–CH a-ketoglutarate CH, CH isocitrate NAD+ H+ + NADH In chapters 9 and 10, you were introduced to several classes of organic reactions. These classes include esterification, decarboxylation, hydration reactions, dehydration of alcohols, oxidation of alcohols, oxidation of aldehydes, reduction of aldehydes, and reduction of ketones. Find at least one of these reaction classes in the citric acid cycle. List the reaction number and the reaction. Write a…arrow_forwardPerform a pyruvate dehydrogenase reaction and a single turn of the citric acid cycle using an oxaloacetate molecule uniformly labeled with 18O and one pyruvate molecule uniformly labeled with 14C. Highlight the fate of all radioactively labeled atoms when complete.arrow_forward
- How many ATPs in total are produced from substrate-level phosphorylation in glycolysis and the citric acid cycle?arrow_forwardhow many net ATP molecules does the citric acid cycle generate in total? Consider both ATP generated directly by the citric acid cycle and ATP generated downstream in oxidative phosphorylation using other molecuies generated by the citric acid cycle For your answer, consider ATP and GTP to be equivalent A) 32 B) 20 C) 2 D) 10 E) 1arrow_forwardName the molecules that conserve most of the energy from the redox reactions of the citric acid cycle (see Figure 9.12). How is this energy converted to a form that can be used to make ATP?arrow_forward
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