Chapter 7, Problem 2EQ

In the experiment of Figure 7.1, Lederberg and Tatum could not discern whether $me{t}^{+}bi{o}^{+}$ genetic material was transferred to the $me{t}^{-}bi{o}^{-}th{r}^{+}le{u}^{+}th{i}^{+}$ strain or if $th{r}^{+}le{u}^{+}th{i}^{+}$ genetic material was transferred to the $me{t}^{+}bi{o}^{+}th{r}^{-}le{u}^{-}th{i}^{-}$ strain. Let’s suppose that one strain is streptomycin-resistant (say, $me{t}^{+}bi{o}^{+}th{r}^{-}le{u}^{-}th{i}^{-}$) and the other strain is sensitive to streptomycin. Describe an experiment that could determine whether the $me{t}^{+}bi{o}^{+}$ genetic material was transferred to the $me{t}^{-}bi{o}^{-}th{r}^{+}le{u}^{+}th{i}^{+}$ strain or the $th{r}^{+}le{u}^{+}th{i}^{+}$ genetic material was transferred to the $me{t}^{+}bi{o}^{+}th{r}^{-}le{u}^{-}th{i}^{-}$ strain. $bi{o}^{+}th{r}^{-}le{u}^{-}th{i}^{-}$ strain.