Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 7, Problem 26ESP
In mice, the X-linked dominant mutation Testicular feminization (Tfm) eliminates the normal response to the testicular hormone testosterone during sexual differentiation. An XY mouse bearing the Tfm allele on the X chromosome develops testes, but no further male differentiation occurs—the external genitalia of such an animal are female. From this information, what might you conclude about the role of the Tfm gene product and the X and Y chromosomes in sex determination and sexual differentiation in mammals? Can you devise an experiment, assuming you can “genetically engineer” the chromosomes of mice, to test and confirm your explanation?
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Chapter 7 Solutions
Concepts of Genetics (12th Edition)
Ch. 7 - Campomelic dysplasia (CMD1) is a congenital human...Ch. 7 - Carbon Copy (CC), the first car produced from a...Ch. 7 - Gender is someones conscious and unconscious...Ch. 7 - Gender is someones conscious and unconscious...Ch. 7 - HOW DO WE KNOW? In this chapter, we have focused...Ch. 7 - Review the Chapter Concepts list on p. 151. These...Ch. 7 - Distinguish between the concepts of sexual...Ch. 7 - Contrast the XX/XY and XX/X0 modes of sex...Ch. 7 - Describe the major difference between sex...Ch. 7 - How do mammals, including humans, solve the dosage...
Ch. 7 - The phenotype of an early-stage human embryo is...Ch. 7 - What specific observations (evidence) support the...Ch. 7 - Describe how nondisjunction in human female...Ch. 7 - An insect species is discovered in which the...Ch. 7 - When cows have twin calves of unlike sex...Ch. 7 - An attached-X female fly, XXY (see the Insights...Ch. 7 - Assume that on rare occasions the attached X...Ch. 7 - It has been suggested that any male-determining...Ch. 7 - What is a Barr body, and where is it found in a...Ch. 7 - Indicate the expected number of Barr bodies in...Ch. 7 - Define the Lyon hypothesis.Ch. 7 - Can the Lyon hypothesis be tested in a human...Ch. 7 - Predict the potential effect of the Lyon...Ch. 7 - Cat breeders are aware that kittens expressing the...Ch. 7 - In mice, the Sry gene (see Section 7.2) is located...Ch. 7 - The genes encoding the red-and...Ch. 7 - What is the role of the enzyme aromatase in sexual...Ch. 7 - In the wasp Bracon hebetor, a form of...Ch. 7 - The Amami spiny rat (Tokudaia osimensis) lacks a Y...Ch. 7 - In mice, the X-linked dominant mutation Testicular...Ch. 7 - When the cloned cat Carbon Copy (CC) was born (see...Ch. 7 - In reptiles, sex determination was thought to be...Ch. 7 - In chickens, a key gene involved in sex...
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