Human Physiology: An Integrated Approach (7th Edition)
Human Physiology: An Integrated Approach (7th Edition)
7th Edition
ISBN: 9780321981226
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 7, Problem 22RQ
Summary Introduction

To determine: The long-loop mechanism of negative feedback.

Introduction: Positive and the negative feedbacks are the types of responses that are offered during a metabolic pathway. In the negative feedback, the response always counteracts the particular stimulus; whereas, in the positive feedback, a response always reinforces the stimulus.

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The metabolic pathway below is used for the production of the purine nucleotides adenosine monophosphate (AMP) and guanosine monophosphate (GMP) in eukaryotic cells. Assume each arrow represents a reaction catalyzed by a different enzyme. Using the principles of feedback inhibition, propose a regulatory scheme for this pathway that ensures an adequate supply of both AMP and GMP, and prevents the buildup of Intermediates A through G when supplies of both AMP and GMP are adequate.
QUESTION 27 Label the structures marked A, B, C and explain the role of structure A. W plasma membrane For the toolbar, press ALT+F10 (PC) or ALT+FN+F10 (Mac). BIUS ☐ Paragraph Π " ΩΘΗ Β Open Sans, a... 10pt EE
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Human Physiology: An Integrated Approach (7th Edition)

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