WHAT IS LIFE? A GUIDE TO BIO 3E+LAUNCHPA
3rd Edition
ISBN: 9781319103316
Author: PHELAN
Publisher: Macmillan Higher Education
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Chapter 7, Problem 13MC
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A male with an X chromosome carrying an allele for a condition will be affected by the condition.
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Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is notexpressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI:
A boy was born without amelogenesis imperfecta
A girl was born without amelogenesis imperfecta
A boy was born with severe amelogenesis imperfecta
A boy was born with non severe amelogenesis imperfecta
Identify the parental genotypes.
Complete the Punnett square for the parental cross, and identify the possible…
Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is not expressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI:
A boy was born without amelogenesis imperfecta
A girl was born without amelogenesis imperfecta
A boy was born with severe amelogenesis imperfecta
A boy was born with non severe amelogenesis imperfecta
Identify the parental genotypes.
Complete the Punnett square for the parental cross, and identify the…
It is determined that Elsa is experiencing beta-thalassemia major. Which of the following statements is NOT true regarding this diagnosis?
The cause of beta-thalassemia is genetic.
Beta-thalassemia major is a grave condition and has a high mortality rate.
Beta-thalassemia major is often treated with blood transfusions.
Because beta-thalassemia is an x-linked trait, it affects males more often than females.
Chapter 7 Solutions
WHAT IS LIFE? A GUIDE TO BIO 3E+LAUNCHPA
Ch. 7 - Prob. 1SACh. 7 - Prob. 2SACh. 7 - Prob. 3SACh. 7 - Prob. 4SACh. 7 - Prob. 5SACh. 7 - Prob. 6SACh. 7 - Prob. 7SACh. 7 - Prob. 8SACh. 7 - Prob. 9SACh. 7 - Prob. 10SA
Ch. 7 - Prob. 11SACh. 7 - Prob. 12SACh. 7 - Prob. 13SACh. 7 - Prob. 14SACh. 7 - Prob. 15SACh. 7 - Prob. 1MCCh. 7 - Prob. 2MCCh. 7 - Prob. 3MCCh. 7 - Prob. 4MCCh. 7 - Prob. 5MCCh. 7 - Prob. 6MCCh. 7 - Prob. 7MCCh. 7 - Prob. 8MCCh. 7 - Prob. 9MCCh. 7 - Prob. 10MCCh. 7 - Prob. 11MCCh. 7 - Prob. 12MCCh. 7 - Prob. 13MCCh. 7 - Prob. 14MCCh. 7 - Prob. 15MCCh. 7 - Prob. 16MC
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- Faulty Tooth Enamel Formation Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is notexpressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI: A boy was born without amelogenesis imperfecta A girl was born without amelogenesis imperfecta A boy was born with severe amelogenesis imperfecta A boy was born with non severe amelogenesis imperfecta Identify the parental genotypes. Complete the Punnett square for the parental…arrow_forwardAn individual with 46, XX genotype is diagnosed with Duchenne-type Muscular Dystrophy, a recessive X-linked disorder. Genetic tests confirm that this individual is a heterozygote for this disorder. Briefly, but specifically, explain how it’s possible that they are showing symptoms of this disorder.arrow_forward3) Queen Victoria of England, who ruled from 1837-1901, is believed to have been the carrier of hemophilia. Hemophilia is an X-linked disease in which the blood is unable to form clots. Please make a Punnet Square using the scenario below and answer the following questions. Queen Victoria married a man who did not have the hemophilia trait or disease. What is the likelihood that they would have a child with hemophilia? What is the likelihood that they would have a son with hemophilia? What is the likelihood that they would have a daughter with hemophilia?arrow_forward
- Hemophilia is another example of an X-linked disease caused when a recessive allele (Xh) is expressed. If a normal male reproduces with a heterozygous normal female, what are the expected genotypes and phenotypes? Will any of their daughters develop hemophilia?arrow_forwardLauren reports that she had a maternal male cousin (through a maternal aunt) and a maternal great uncle (maternal grandmother’s brother) both pass away from the same x-linked lethal condition. Both affected individuals did not have genetic testing. Lauren has a normal carrier screen for x-linked lethal conditions, which you know identifies 40% of causative mutations. If Lauren is currently pregnant with a male child, what is the chance that this child will have the condition?arrow_forwardHemophilia A is caused by a recessive X-linked allele that encodes a defective form of a clotting protein. If a affected father and a mother who is known to not be a carrier have children, what percentage of female offspring will have hemophilia?arrow_forward
- X-linked disorders (like hemophilia) are more likely to affect people of one gender than the other. Which gender is this, and why are x-linked disorders more likely to affect people of this gender?arrow_forwardDuchenne muscular dystrophy is sex linked and usuallyaffects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brotherhas Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’sdisease, what is the probability that you have receivedthe allele?c. If your father’s brother had the disease, what is theprobability that you have received the allele?arrow_forwardHaemophilia A is a severe coagulation disorder that shows X-linked recessive inheritance. Red-green colour blindness also shows X- linked recessive inheritance. A man with both haemophilia A and colour blindness is referred for genetic counselling. Assume that his partner is not a carrier of either of these conditions. Which of the following is correct? OA. The probability that each of his daughters will be a carrier of haemophilia A is 1 in 2. OB. The probability that each of his sons will be affected with haemophilia A is 1 in 2. OC. he probability that each of his daughters will be a carrier of haemophilia A and colour blindness is 1 in 2. D. The probability that each of his sons will be affected with both haemophilia A and colour blindness is 1 in 2. OE. The probability that each of his daughters will be a carrier of both haemophilia A and colour blindness conditions is 1.arrow_forward
- X-linked lissencephaly is an X-link dominant trait pertaining to a brain disorder. It superficially resembles an autosomal dominant trait because both the daughters and sons of an affected female parent can be affected. Mr. Panganiban is affected by the said disorder while his wife is not. Using your knowledge in predicting the genetic possibilities of the offspring, what do you think would happen to their sons and daughters in the first filial generation? Females affected by an X-link dominant have 50% for their sons and daughters to be affected. Father affected by the X-linked dominant trait can transmit the trait to all his daughters. Males with lissencephaly could transmit the genetic disorder for both sons and daughters. Lissencephaly is an X-link limited dominant trait. It usually affects males because they have only a single chromosome.arrow_forwardPlease provide detailed explanationarrow_forwardHemophilia is another example of a X-linked disease caused when a recessive allele (Xh) is expressed. If a normal male reproduces with a heterozygous normal female, what are the expected genotypes and phenotypes? Will any of their daughters develop hemophilia? As in the previous question, you must also give the gender of the child in your genotype and phenotype descriptions here.arrow_forward
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