CAMPBELL BIOLOGY-MASTERING BIO.ACCESS
CAMPBELL BIOLOGY-MASTERING BIO.ACCESS
12th Edition
ISBN: 9780136486787
Author: Urry
Publisher: SAVVAS L
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Chapter 6.6, Problem 1CC
Summary Introduction

To find: The way in which cilia and flagella bend.

Concept introduction:

Cilia and flagella are specialized arrangements of microtubules. It helps in the movement of sperm, algae and sweeping mucus containing trapped debris. A flagellum has undulating movement andcilia have alternative power and recovery strokes. Microtubules are hollow tubes of 25nm diameter. It is made of tubulin protein. It is important for the maintenance of cell shape and motility. In both cilia and flagella, microtubules are arranged in “9+2” pattern. There are two microtubules at the center and nine microtubules at the periphery. At the periphery, microtubules are present in doublet. The microtubules of cilia and flagella are attached with basal body. Basal body has “9+0” pattern of arrangement. There are zero microtubules at the center and nine microtubules at the periphery.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

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