LAUNCHPAD F/WHAT IS LIFE
4th Edition
ISBN: 9781319231897
Author: PHELAN
Publisher: Macmillan Higher Education
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Chapter 6, Problem 9MC
Summary Introduction
Introduction:
Mutations are changes in the sequence of nitrogenous bases in DNA.
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Which of the following terms refer to the case when a mutation results in a significant decrease or a complete loss of the functional activity of a gene product?
a. gain-of-function mutation
b. loss-of-function mutation
Which of the following is NOT true about mutations?
A. Mutations can be harmful but not beneficial to the cell
B. Nucleotide substitution in DNA can cause nonsense mutations
C. Nucleotide substitution in DNA can cause missense mutations
D. Mutagens increase the rate of mutation, but mutations are still random
E. Nucleotide insertion or deletion in DNA can cause frameshift mutations
Which of the following statements best describes the outcome of a mutation?
a.
A mutation always results in a mutant genotype
b.
A mutation always results in a mutant karyotype
c.
A mutation always results in a mutant phenotype
d.
A mutation always results in a mutant protein
Chapter 6 Solutions
LAUNCHPAD F/WHAT IS LIFE
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Which of the following is true about the enzyme telomerase? A. It is found only in adult cells. B. It is responsible for telomere shortening. C. It can re-establish telomere length. D. It may speed up the aging process. E. It is expressed at low levels in cancer cells.arrow_forward18) MUTATIONS: A. Explain the difference between a point mutation and a frameshift mutation. B. Explain how the mutation (both a point mutation and frameshift mutation) might impact the production of proteins. C. Name one type of chromosome mutation and explain what it is.arrow_forwardWhich statement(s) below regarding DNA mutations is true: A. Mutations only occur in genes B. Mutations always result in phenotypic alterations C. Mutations are only induced by extrinsic (environmental) factors D. Mutations can occur in promoters E. Point mutations can be caused by transposons or “jumping genes”arrow_forward
- A.) There is no change in the DNA sequence if nucleotides are added or removed, it will have no effect to the cell. B.) Mutations in the DNA sequence are all irreversible. A. Statement A is correct B. Statement B is correct C. Both A and B are correct D. Both A and B are incorrectarrow_forwardWith regard to human cancer cells, which of the following statements is true? A. Cancer cells within one tumor usually do not share common mutations B. Cancer cells generally have lost the ability to divide C. Oncogenes are non-human genes not related to normal genes in the human genome D. Mutations in DNA repair genes result in an increased chance of getting cancer.arrow_forwardWhen using gene therapy to treat an hereditary disease, the idea is to: A. Introduce the correct gene into the patient's DNA B. Inject the patient with a specific protein to cure the disease. C. Blood transfusions from healthy individuals. D. ntroduce mRNA molecules with the correct genetic information to the patient. E. Introduce a virus to the patient that will specifically destroy mutated cells.arrow_forward
- A genetic researcher notices that individuals with a particular genetic disease have a shortened version of key protein involved in the diseased biochemical pathway. Which of the following mutations is most likely to result in the premature termination of protein synthesis? A. The disease is caused by a silent mutation. B. The disease is caused by a frameshift mutation. C. The disease is caused by a missense mutation. D. The disease is caused by a nonsense mutation.arrow_forwardA protein is normally secreted from the cell. A team of scientists attempts to redirect this protein to the inside of the nucleus by mutating the sequence of the gene. Unfortunately, after this mutation, the protein is no longer secreted, but it is now localized to the cytosol and not the nucleus. Briefly answer the two questions below: Identify the sequence that was mutated by the scientists and explain your reasoning. a. b. What additional mutation must be made by the scientists to redirect this protein to the nucleus? Explain your reasoning.arrow_forwardFor each statement below indicate whether it is true or false: A. Strand discrimination during the process of DNA repair is based on DNA methylation B. The genetic code has 64 amino acid-specifying codons C. Mutations in germline cells are more consequential to subsequent generations than mutations in somatic cells.arrow_forward
- Which of the following statements is true about the effects of mutations in somatic cells and gametes? A. Only mutations in gametes can affect future generations. B. Only mutations in somatic cells can affect future generations. C. Neither mutations in somatic cells or gametes can affect future generations. D. Mutations in both somatic cells and gametes can affect future generations.arrow_forwardWhich of the following types of mutations will have the most devastating effect on a cell?A.frameshift mutationB. missense mutationC. nonsense mutationD. silent mutationarrow_forwardPlease read the scenario below and then answer the question (in bold) that follows. An original DNA sequence reads 3'- GGCGCTAGAATC -5'. A mutated version of that DNA strand is produced that reads 3-GGCTCTAGAATC -5. Based on the information above, how severe of an impact do you believe the mutation would have on the cell (and therefore individual) in which the mutation occurred? O a. Very severe, because the mutation leads to the formation of a truncated polypeptide O b. Moderately to very severe, because the mutation results in the formation of a polypeptide that contains amino acids not found in the unmutated polypeptide O c. Likely not that severe, because the amino acid sequence of the mutated polypeptide is identical to the amino acid sequence of the nonmutated polypeptidearrow_forward
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