Fundamentals of Biostatistics
Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 6, Problem 58P

The etiology of high blood pressure remains a subject of active investigation. One widely accepted hypothesis is that excessive sodium intake adversely affects blood-pressure Data set available outcomes. To explore this hypothesis, an experiment was set up to measure responsiveness to the taste of salt and to relate the responsiveness to blood-pressure level. The protocol used involved giving 3-day-old infants in the newborn nursery a drop of various solutions, thus eliciting the sucking response and noting the vigor with which they sucked—denoted by MSB (mean number of sucks per burst of sucking). The content of the solution was changed over 10 consecutive periods: (1) water, (2) water, (3) 0.1 molar salt + water, (4) 0.1 molar salt + water, (5) water, (6) water, (7) 0.3 molar salt + water, (8) 0.3 molar salt + water, (9) water, (10) water. In addition, as a control, the response of the baby to the taste of sugar was also measured after the salt-taste protocol was completed. In this experiment, the sucking response was measured over five different periods with the following stimuli: (1) nonnutritive sucking, that is, a pure sucking response was elicited without using any external substance; (2) water; (3) 5% sucrose + water; (4) 15% sucrose + water; (5) nonnutritive sucking.

The data for the first 100 infants in the study are given in Data Set INFANTBP.DAT. The format of the data is given in Data Set INFANTBP.DOC at www.cengagebrain.com.

Construct a variable measuring the response to salt. For example, one possibility is to compute the average MSB for trials 3 and 4 − average MSB for trials 1 and 2 = average MSB when the solution was 0.1 molar salt + water – average MSB when the solution was water. A similar index could be computed comparing trials 7 and 8 with trials 5 and 6.

We want to relate the indices to blood-pressure level. Provide a scatter plot relating mean SBP and mean DBP, respectively, to each of the salt-taste and sugar-taste indices. Does there appear to be a relation between the indices and blood-pressure level? We discuss this in more detail in our work on regression analysis in Chapter 11.

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Chapter 6 Solutions

Fundamentals of Biostatistics

Ch. 6 - The data in Table 6.10 concern the mean triceps...Ch. 6 - The data in Table 6.10 concern the mean triceps...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - A nine-laboratory cooperative study was performed...Ch. 6 - A nine-laboratory cooperative study was performed...Ch. 6 - A nine-laboratory cooperative study was performed...Ch. 6 - A nine-laboratory cooperative study was performed...Ch. 6 - A nine-laboratory cooperative study was performed...Ch. 6 - A study of psychological and physiological health...Ch. 6 - A study of psychological and physiological health...Ch. 6 - A study is conducted to test the hypothesis that...Ch. 6 - A study is conducted to test the hypothesis that...Ch. 6 - Suppose a clinical trial is conducted to test the...Ch. 6 - Suppose a clinical trial is conducted to test the...Ch. 6 - Suppose a clinical trial is conducted to test the...Ch. 6 - Suppose we want to estimate the concentration...Ch. 6 - Suppose we want to estimate the concentration...Ch. 6 - Suppose we want to estimate the concentration...Ch. 6 - Much discussion has taken place concerning...Ch. 6 - Much discussion has taken place concerning...Ch. 6 - Much discussion has taken place concerning...Ch. 6 - A new assay is developed to obtain the...Ch. 6 - A new assay is developed to obtain the...Ch. 6 - A new assay is developed to obtain the...Ch. 6 - A new assay is developed to obtain the...Ch. 6 - Suppose 100 hypertensive people are given an...Ch. 6 - Suppose 100 hypertensive people are given an...Ch. 6 - Suppose 100 hypertensive people are given an...Ch. 6 - Suppose we decide a better measure of the...Ch. 6 - Suppose we decide a better measure of the...Ch. 6 - Suppose we decide a better measure of the...Ch. 6 - Suppose we decide a better measure of the...Ch. 6 - Draw six random samples of size 5 from the data in...Ch. 6 - Draw six random samples of size 5 from the data in...Ch. 6 - Draw six random samples of size 5 from the data in...Ch. 6 - Draw six random samples of size 5 from the data in...Ch. 6 - Draw six random samples of size 5 from the data in...Ch. 6 - Figure 6.4b (p. 172) plotted the sampling...Ch. 6 - Figure 6.4b (p. 172) plotted the sampling...Ch. 6 - Figure 6.4b (p. 172) plotted the sampling...Ch. 6 - Figure 6.4b (p. 172) plotted the sampling...Ch. 6 - The etiology of high blood pressure remains a...Ch. 6 - The etiology of high blood pressure remains a...Ch. 6 - The etiology of high blood pressure remains a...Ch. 6 - Data Set SEXRAT.DAT, at www.cengagebrain.com,...Ch. 6 - A cohort of hemophiliacs is followed to elicit...Ch. 6 - A cohort of hemophiliacs is followed to elicit...Ch. 6 - A cohort of hemophiliacs is followed to elicit...Ch. 6 - We have previously described Data Set LEAD.DAT (at...Ch. 6 - We have previously described Data Set LEAD.DAT (at...Ch. 6 - We have previously described Data Set LEAD.DAT (at...Ch. 6 - Data Set NIFED.DAT (at www.cengagebrain.com) was...Ch. 6 - Data Set NIFED.DAT (at www.cengagebrain.com) was...Ch. 6 - Data Set NIFED.DAT (at www.cengagebrain.com) was...Ch. 6 - Suppose that there are 6 deaths due to bladder...Ch. 6 - Suppose that there are 4 deaths due to stomach...Ch. 6 - The value of mammography as a screening test for...Ch. 6 - The value of mammography as a screening test for...Ch. 6 - The value of mammography as a screening test for...Ch. 6 - The value of mammography as a screening test for...Ch. 6 - On the computer, draw 1000 bootstrap samples of...Ch. 6 - On the computer, draw 1000 bootstrap samples of...Ch. 6 - A study was performed to investigate the...Ch. 6 - A study was performed to investigate the...Ch. 6 - Refer to Data Set BONEDEN.DAT at...Ch. 6 - Refer to Data Set BONEDEN.DAT at...Ch. 6 - Prob. 88PCh. 6 - Prob. 89PCh. 6 - Prob. 90PCh. 6 - Prob. 91PCh. 6 - Prob. 92PCh. 6 - Prob. 93PCh. 6 - Prob. 94PCh. 6 - Prob. 95PCh. 6 - Prob. 96PCh. 6 - A patient who is taking antihypertensive...Ch. 6 - A patient who is taking antihypertensive...Ch. 6 - A patient who is taking antihypertensive...Ch. 6 - A patient who is taking antihypertensive...Ch. 6 - A patient who is taking antihypertensive...Ch. 6 - Injuries are common in football and may be related...Ch. 6 - Injuries are common in football and may be related...Ch. 6 - A hypertensive patient has been on...Ch. 6 - A hypertensive patient has been on...Ch. 6 - A hypertensive patient has been on...Ch. 6 - A hypertensive patient has been on...Ch. 6 - A radiologist investigates whether a new (less...Ch. 6 - A radiologist investigates whether a new (less...Ch. 6 - The estimation of allele probabilities is...Ch. 6 - The estimation of allele probabilities is...Ch. 6 - The estimation of allele probabilities is...Ch. 6 - As an experiment, 10,000 people are completely...Ch. 6 - As an experiment, 10,000 people are completely...Ch. 6 - Which of the following sample results yields a 95%...Ch. 6 - Suppose we observe 30 cases of colon cancer over...
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