Fundamentals of Biostatistics
Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 6, Problem 110P

The estimation of allele probabilities is essential for the closer quantitative identification of inheritance. It requires the probabilistic formulation of the applied model of inheritance. The hereditary disease phenylketonuria (PKU) is a useful example. PKU follows a recessive form of inheritance. Suppose there are two alleles at a gene locus denoted by a and A where the possible genotypes are (aa), (aA), and (AA). An individual will only be affected if the genotype aa appears (i.e., a recessive form of inheritance).

Suppose the probability of an a allele is p. If people mate randomly, then what is the probability of the (aa) genotype?

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Chapter 6 Solutions

Fundamentals of Biostatistics

Ch. 6 - The data in Table 6.10 concern the mean triceps...Ch. 6 - The data in Table 6.10 concern the mean triceps...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - Refer to the data in Table 2.13. Regard this...Ch. 6 - A nine-laboratory cooperative study was performed...Ch. 6 - A nine-laboratory cooperative study was performed...Ch. 6 - A nine-laboratory cooperative study was performed...Ch. 6 - A nine-laboratory cooperative study was performed...Ch. 6 - A nine-laboratory cooperative study was performed...Ch. 6 - A study of psychological and physiological health...Ch. 6 - A study of psychological and physiological health...Ch. 6 - A study is conducted to test the hypothesis that...Ch. 6 - A study is conducted to test the hypothesis that...Ch. 6 - Suppose a clinical trial is conducted to test the...Ch. 6 - Suppose a clinical trial is conducted to test the...Ch. 6 - Suppose a clinical trial is conducted to test the...Ch. 6 - Suppose we want to estimate the concentration...Ch. 6 - Suppose we want to estimate the concentration...Ch. 6 - Suppose we want to estimate the concentration...Ch. 6 - Much discussion has taken place concerning...Ch. 6 - Much discussion has taken place concerning...Ch. 6 - Much discussion has taken place concerning...Ch. 6 - A new assay is developed to obtain the...Ch. 6 - A new assay is developed to obtain the...Ch. 6 - A new assay is developed to obtain the...Ch. 6 - A new assay is developed to obtain the...Ch. 6 - Suppose 100 hypertensive people are given an...Ch. 6 - Suppose 100 hypertensive people are given an...Ch. 6 - Suppose 100 hypertensive people are given an...Ch. 6 - Suppose we decide a better measure of the...Ch. 6 - Suppose we decide a better measure of the...Ch. 6 - Suppose we decide a better measure of the...Ch. 6 - Suppose we decide a better measure of the...Ch. 6 - Draw six random samples of size 5 from the data in...Ch. 6 - Draw six random samples of size 5 from the data in...Ch. 6 - Draw six random samples of size 5 from the data in...Ch. 6 - Draw six random samples of size 5 from the data in...Ch. 6 - Draw six random samples of size 5 from the data in...Ch. 6 - Figure 6.4b (p. 172) plotted the sampling...Ch. 6 - Figure 6.4b (p. 172) plotted the sampling...Ch. 6 - Figure 6.4b (p. 172) plotted the sampling...Ch. 6 - Figure 6.4b (p. 172) plotted the sampling...Ch. 6 - The etiology of high blood pressure remains a...Ch. 6 - The etiology of high blood pressure remains a...Ch. 6 - The etiology of high blood pressure remains a...Ch. 6 - Data Set SEXRAT.DAT, at www.cengagebrain.com,...Ch. 6 - A cohort of hemophiliacs is followed to elicit...Ch. 6 - A cohort of hemophiliacs is followed to elicit...Ch. 6 - A cohort of hemophiliacs is followed to elicit...Ch. 6 - We have previously described Data Set LEAD.DAT (at...Ch. 6 - We have previously described Data Set LEAD.DAT (at...Ch. 6 - We have previously described Data Set LEAD.DAT (at...Ch. 6 - Data Set NIFED.DAT (at www.cengagebrain.com) was...Ch. 6 - Data Set NIFED.DAT (at www.cengagebrain.com) was...Ch. 6 - Data Set NIFED.DAT (at www.cengagebrain.com) was...Ch. 6 - Suppose that there are 6 deaths due to bladder...Ch. 6 - Suppose that there are 4 deaths due to stomach...Ch. 6 - The value of mammography as a screening test for...Ch. 6 - The value of mammography as a screening test for...Ch. 6 - The value of mammography as a screening test for...Ch. 6 - The value of mammography as a screening test for...Ch. 6 - On the computer, draw 1000 bootstrap samples of...Ch. 6 - On the computer, draw 1000 bootstrap samples of...Ch. 6 - A study was performed to investigate the...Ch. 6 - A study was performed to investigate the...Ch. 6 - Refer to Data Set BONEDEN.DAT at...Ch. 6 - Refer to Data Set BONEDEN.DAT at...Ch. 6 - Prob. 88PCh. 6 - Prob. 89PCh. 6 - Prob. 90PCh. 6 - Prob. 91PCh. 6 - Prob. 92PCh. 6 - Prob. 93PCh. 6 - Prob. 94PCh. 6 - Prob. 95PCh. 6 - Prob. 96PCh. 6 - A patient who is taking antihypertensive...Ch. 6 - A patient who is taking antihypertensive...Ch. 6 - A patient who is taking antihypertensive...Ch. 6 - A patient who is taking antihypertensive...Ch. 6 - A patient who is taking antihypertensive...Ch. 6 - Injuries are common in football and may be related...Ch. 6 - Injuries are common in football and may be related...Ch. 6 - A hypertensive patient has been on...Ch. 6 - A hypertensive patient has been on...Ch. 6 - A hypertensive patient has been on...Ch. 6 - A hypertensive patient has been on...Ch. 6 - A radiologist investigates whether a new (less...Ch. 6 - A radiologist investigates whether a new (less...Ch. 6 - The estimation of allele probabilities is...Ch. 6 - The estimation of allele probabilities is...Ch. 6 - The estimation of allele probabilities is...Ch. 6 - As an experiment, 10,000 people are completely...Ch. 6 - As an experiment, 10,000 people are completely...Ch. 6 - Which of the following sample results yields a 95%...Ch. 6 - Suppose we observe 30 cases of colon cancer over...
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