1 SEM ACC W/RAVEN CARDED
12th Edition
ISBN: 9781265486297
Author: Raven
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Textbook Question
Chapter 50, Problem 5A
If you wanted to cure allergies by bioengineering an antibody that would bind and disable the antibody responsible for allergic reactions,
which of the following would you target?
a. IgG
b. IgA
c. IgE
d. IgD
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Students have asked these similar questions
Explain why each choice (a-d) is correct or incorrect.
Allergens differ from antigens because
a. Allergens produce an abnormally large immune response to what is an otherwise harmless particle.
b. Allergens do not involve the leucocytes, they simple stimulate the inflammatory response.
c. Allergens are only active seasonally and are generally harmless to the body.
d. Allergens are primarily plant derived while antigens are bacterial or viral in nature.
In the laboratory you observe that IL-4 stimulates the proliferation of B cells, cytotoxic T cells and
mast cells. In this case the effect of IL-4 can be described as:
a. Antagonism
b. Synergy
c. Redundancy
d. Pleiotropy
Researchers can make monoclonal antibodies by immunizing a mouse with a molecule (or with a microorganism). The resulting antibody-mediated response produces a set of antibodies that recognize different parts of the molecule. The mouse's B cells are then harvested from its spleen and fused with cancerous B cells from a myeloma cell line. The resulting hybrid myeloma ("hybridoma") cells are cloned: Individual cells are grown in tissue culture as separate cell lines. Each cell line produces and secretes antibodies that recognize one part of the immunizing molecule. These antibodies are called monoclonal antibodies, and they can be purified and used for research or other purposes. Monoclonal antibodies are effective for passive immunization, but only in the immediate term. Antibodies produced by one's own immune system can last up to about six months in the bloodstream, but monoclonals delivered in passive immunization often last for less than a week. Why the difference?
Chapter 50 Solutions
1 SEM ACC W/RAVEN CARDED
Ch. 50.1 - Prob. 1LOCh. 50.1 - Prob. 2LOCh. 50.1 - Prob. 3LOCh. 50.2 - Prob. 1LOCh. 50.2 - Prob. 2LOCh. 50.2 - Prob. 3LOCh. 50.3 - Prob. 1LOCh. 50.3 - Prob. 2LOCh. 50.4 - Explain how antibody diversity is generated.Ch. 50.4 - Prob. 2LO
Ch. 50.4 - Prob. 3LOCh. 50.5 - Define autoimmune diseases.Ch. 50.5 - Prob. 2LOCh. 50.6 - Explain antigenantibody reactions in the ABO blood...Ch. 50.6 - Prob. 2LOCh. 50.6 - Prob. 3LOCh. 50.7 - Prob. 1LOCh. 50.7 - Prob. 2LOCh. 50 - How would a high level of HCG present in a urine...Ch. 50 - What would happen if an NK cell killed a virally...Ch. 50 - Prob. 2IQCh. 50 - Prob. 3IQCh. 50 - Prob. 4IQCh. 50 - Cells that target and kill body cells infected by...Ch. 50 - Structures on invading cells recognized by the...Ch. 50 - Which one of the following acts as the alarm...Ch. 50 - Prob. 4UCh. 50 - Receptors that trigger innate immune responses a....Ch. 50 - Diseases in which the persons immune system no...Ch. 50 - Suppose that a new disease is discovered that...Ch. 50 - You start a new job in a research lab. The lab...Ch. 50 - In comparing T-cell receptors and immunoglobulins...Ch. 50 - If you have type AB blood, which of the following...Ch. 50 - Suppose that you get a paper cut while studying....Ch. 50 - If you wanted to cure allergies by bioengineering...Ch. 50 - Why do we need to be repeatedly vaccinated for...Ch. 50 - Prob. 7ACh. 50 - Suppose you take a job in the marketing department...Ch. 50 - Prob. 2SCh. 50 - Prob. 3SCh. 50 - Toll-like receptors have been found in a wide...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Which of the following statements is true? A. Hypersensitivity requires previous exposure to an antigen B. Hypersensitivity is due to the presence of a virus. C. Hypersensitivity occurs in the absence of an antigen. D. Hypersensitivity is synonymous with the term " infection". E. Hypersensitivity occurs when an individual is exposed to an allergen for the first time.arrow_forwardTuberculosis is a chronic respiratory condition caused by Mycobacterium tuberculosis, a high contagious bacterium. People with tuberculosis will often have a persistent (sometimes bloody) cough, fatigue, weight loss, and fever. M. tuberculosis produces a protein we will call “X”. A new test for tuberculosis checks for X antibodies in a person’s blood. If the antibodies are present, the result is “positive.” Why would X antibodies be present in someone’s blood? What specific kind of cells would produce them?arrow_forwardDefine the following terms: a. tus-ter complex b. chimera c. MHC antigens d. helices e. primerarrow_forward
- A researcher performs an experiment where he infects 2 mice (Mouse A and Mouse B) with herpes simplex virus (HSV). To measure the cytotoxicity of CD8+ T cells from Mouse A, he isolates CD8+ T cells from Mouse A and co-cultures them with a mixture of HSV-infected spleen cells from Mouse B. A day later, he checks the co-culture, but none of the infected spleen cells from Mouse B have been killed. What could explain this observation? a.Mouse B does not express the invariant chain (Ii) b.Mouse A and Mouse B express different MHC alleles c.Mouse A does not express TLR2/6 d.HSV immunoevasins block MHC-II expressionarrow_forwardIn the figure below, which close-up view of these two V domains has the amino acid sequences most important for antigen-binding highlighted correctly in red?arrow_forwardTuberclosis is a chronic respiratory condition caused by Mycobacterium tuberculosis, a highly contagious bacterium. People with tuberculosis will often have a persistent (sometimes bloody) cough, fatigue, weight loss, and fever. M. tuberculosis produces a protein we will call "X." A new test for tuberculosis checks for X antibodies in a person's blood. If the antibodies are present, the result is positive. Why would X antibodies be present in someone's blood What specific kind of cells would produce them?arrow_forward
- Vaccines are given to provide protection against pathogen causing infections. Which of the following statements best describes how vaccines work? a Fever and swelling develop which is the first response in killing a pathogen b. Antibodies in the vaccine provide the body with nonspecific immunity to an antigen. c. An inactivated or killed virus stimulates the body to develop specific immunity to that type of virus. d. Heathy bacteria causes the body to release toxins which will protect the body if later exposed to different type of bacteria.arrow_forwardHypothetically, HPV was used to cure cancer where the cancer was recognized to be foreign by our host immune response. So therefore, which of the following best illustrates how HPV was used to cure cancer?a. The HPV induced a type IV hypersensitivity immune responseb. The HPV induced a type III hypersensitivity immune responsec. The HPV induced a type II hypersensitivity immune responsed. The HPV induced a type I hypersensitivity immune responsee. The HPV induced a type IV autoimmune responsearrow_forwardWhich of the following best defines MHC restriction? Select one: a. The TCR recognizes a particular epitope in the context of a specific MHC molecule. b. Any given MHC molecule is able to bind a wide variety of epitopes. C. The TCR recognizes only the MHC molecule. Od. The TCR recognizes the epitope bound to any MHC molecule having the correct motif. Oe. A TCR may bind to either an MHC Class I or MHC Class II molecule along with the bound epitope.arrow_forward
- The function of the integrin can be described as follows:a). Media signal translation insideb). Stabilizes the binding of the TCR so that receivers are added and signals are sent insidec). Allows the receiver and its corrector to stick to the antigend). It helps the movement and development of lipid rafts that add and concentrate antigens together with TCRarrow_forwardThis term describes an antigen that is too small to be immunogenic, however it binds to proteins in the body to increase its size, allowing it to then be able to trigger an immune reaction: O 1) hapten O 2) alloantigen 3) superantigen O 4) epitopearrow_forwardWhich of the following statement(s) about DNA vaccines is(are) NOT true? Check all that apply. A.) DNA vaccines are an example of "ex vivo" vaccination; cells are removed from the body, transfected with DNA expressing the antigen(s) of interest, and then the cells are returned to the body. B.) DNA vaccines can be used to immunize with multiple different antigens. C.) DNA vaccines only stimulate B cell responses. D.) DNA vaccines only stimulate T cell responses. DNA vaccines alone often result in poor immunogenicityarrow_forward
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