Essentials of Human Anatomy & Physiology (12th Edition)
12th Edition
ISBN: 9780134395326
Author: Elaine N. Marieb, Suzanne M. Keller
Publisher: PEARSON
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Chapter 5, Problem 3MC
Which of the following would you expect to be prominent in osteoclasts?
a. Golgi apparatus
b. Lysosomes
c. Microfilaments
d. Exocytosis
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Case Study—Ella
Review the case study and then answer Parts A through F.
Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch.
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Chapter 5 Solutions
Essentials of Human Anatomy & Physiology (12th Edition)
Ch. 5 - Multiple Choice
More than one choice may...Ch. 5 - A passageway connecting neighboring osteocytes in...Ch. 5 - 3. Which of the following would you expect to be...Ch. 5 - Prob. 4MCCh. 5 - Prob. 5MCCh. 5 - Prob. 6MCCh. 5 - Which parts of the thoracic vertebrae articulate...Ch. 5 - Which of the following bones or bond parts...Ch. 5 - Which bone of the arm corresponds to the femur of...Ch. 5 - 10. At what stage of life do the lower limbs...
Ch. 5 - 11. Match the types of joints the descriptions...Ch. 5 - Match the bone markings listed on the right with...Ch. 5 - Prob. 13SAECh. 5 - What is yellow marrow? How do spongy and compact...Ch. 5 - Why do bone injuries heal much more rapidly than...Ch. 5 - 16. Compare and contrast the role of PTH (hormone)...Ch. 5 - 17. Which fracture types are most common in older...Ch. 5 - Prob. 18SAECh. 5 - 19. With one exception, all skull bones are joined...Ch. 5 - What facial bone forms the chin? The cheekbone?...Ch. 5 - 21. Name two ways in which the fetal skull differs...Ch. 5 - 22. How many vertebrae are there in each of the...Ch. 5 - Diagram the normal spinal curvatures and then the...Ch. 5 - 24. What is the function of the intervertebral...Ch. 5 - Name the major components of the thorax.Ch. 5 - Is a floating rib a true or a false rib? Why are...Ch. 5 - 27. Name the bones of the shoulder girdle.
Ch. 5 - 28. Name all the bones with which the ulna...Ch. 5 - What bones make up each hip bone (coxal bone)?...Ch. 5 - 30. Name the bones of the lower limb from superior...Ch. 5 - Compare the amount of movement possible in...Ch. 5 - Describe the structure of a synovial joint. Use...Ch. 5 - Prob. 33SAECh. 5 - Prob. 34SAECh. 5 - 35. List two factors that keep bones healthy. List...Ch. 5 - Contrast the location and characteristics of...Ch. 5 - A 75-year-old woman and her 9-year-old...Ch. 5 - Prob. 38CTCh. 5 - After having a severe cold accompanied by nasal...Ch. 5 - Prob. 40CTCh. 5 - Prob. 41CTCh. 5 - 42. An X-ray image of the arm of an accident...Ch. 5 - Prob. 43CTCh. 5 - A patient complains of pain starting in the jaw...Ch. 5 - Prob. 45CTCh. 5 - Prob. 46CT
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