
Concept explainers
(a)
Interpretation:The stereocenter in thalidomide should be identified.
Concept introduction:Chiral carbon is any stereocenter attached to four different alkyl substituents. It is also known as stereocenter. If any two of the substituent happen to be similar the center is regarded as achiral. However, the most essential criteria that help to distinguish a chiral or non-chiral system ispresence of any symmetry element. If any plane center or axis of symmetry is identified it makes molecule achiral and optically inactive.
Thalidomide was originally taken as sedative against morning sickness; while one of its enantiomers was successful as sedative, other enantiomer caused certain birth defects.
(b)
Interpretation:Two enantiomers in thalidomide should be drawn and labeled.
Concept introduction:In order to assign absolute configuration of R and S, Cahn − Ingold − Prelog rules are used and the first step is to assign the priority order on the basis of
The Fischer projection is written along with the priorities assigned and groups are interchanged between adjacent places so as to obtain lowest priority group at the bottom or lowest priority.
If the groups now are arranged are read from highest towards least in clockwise fashion the R is assigned to the stereocenter, if the rotation is anticlockwise the S is assigned at the configuration.
(c)
Interpretation: The relevant hydrogen that shows acidic properties should be identified in thalidomide.
Concept introduction:Thalidomide was originally taken as sedative against morning sickness; while one of its enantiomer was successful as sedative, other enantiomer caused certain birth defects. The two enantiomers of thalidomide are as follows:

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Chapter 5 Solutions
ORGANIC CHEMISTRY (LL)-PACKAGE
- julietteyep@gmail.com X YSCU Grades for Juliette L Turner: Orc X 199 A ALEKS - Juliette Turner - Modul X A ALEKS - Juliette Turner - Modul x G butane newman projection - Gox + www-awa.aleks.com/alekscgi/x/Isl.exe/10_u-IgNslkr7j8P3jH-IBxzaplnN4HsoQggFsejpgqKoyrQrB2dKVAN-BcZvcye0LYa6eXZ8d4vVr8Nc1GZqko5mtw-d1MkNcNzzwZsLf2Tu9_V817y?10Bw7QYjlb il Scribbr citation APA SCU email Student Portal | Main Ryker-Learning WCU-PHARM D MySCU YSCU Canvas- SCU Module 4: Homework (Ch 9-10) Question 28 of 30 (1 point) | Question Attempt: 1 of Unlimited H₂SO heat OH The mechanism of this reaction involves two carbocation intermediates, A and B. Part 1 of 2 KHSO 4 rearrangement A heat B H₂O 2 OH Draw the structure of A. Check Search #t m Save For Later Juliet Submit Assignm 2025 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Center | Accessarrow_forwardThe electrons flow from the electron-rich atoms of the nucleophile to the electrons poor atoms of the alkyl halide. Identify the electron rich in the nucleophile. Enter the element symbol only, do not include any changes.arrow_forwardHello, I am doing a court case analysis in my Analytical Chemistry course. The case is about a dog napping and my role is prosecution of the defendant. I am tasked in the Area of Expertise in Neutron Activation and Isotopic Analysis. Attached is the following case study reading of my area of expertise! The landscaping stone was not particularly distinctive in its decoration but matched both the color and pattern of the Fluential’s landscaping stone as well as the stone in the back of the recovered vehicle. Further analysis of the stone was done using a technique called instrumental neutron activation analysis. (Proceed to Neutron Activation data) Photo Notes: Landscaping stone recovered in vehicle. Stone at Fluential’s home is similar inappearance. Finally, the white paint on the brick was analyzed using stable isotope analysis. The brick recovered at the scene had smeared white paint on it. A couple of pieces of brick in the back of the car had white paint on them. They…arrow_forward
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- What is the product of the following reaction? Please include a detailed explanation of what is happening in this question. Include a drawing showing how the reagent is reacting with the catalyst to produce the correct product. The correct answer is IV.arrow_forwardPlease complete the reactions, thank youarrow_forwardConsider the synthesis. What is compound Y? Please explain what is happening in this question. Provide a detailed explanation and a drawing to show how the compound Y creates the product. The correct answer is D.arrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning

