BIO 1408/09 PKG W/LS CODE
BIO 1408/09 PKG W/LS CODE
5th Edition
ISBN: 9781260370829
Author: Mader
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 5, Problem 2TC

Cystic fibrosis is a genetic disorder that results in a defective membrane transport protein .The defective protein closes chloride ion channels in membranes, preventing chloride ions from being exported out of cells. This results in the development of a thick mucus on the outer surfaces of cells. This mucus clogs the ducts that carry digestive enzymes from the pancreas to the small intestine, clogs the airways in the lungs, and promotes lung infections. Why do you think the defective protein results in a thick, sticky mucus outside the cells, instead of a loose, fluid covering?

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