Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 5, Problem 2ITD
Some cancer cells are insensitive to typical chemotherapy. Research into the mechanisms underlying this insensitivity uncovered an ability by these cells to “pump” the treatment drug out of the cell against its concentration gradient. Additional drugs have been developed that inhibit the pump, thus trapping the chemotherapeutic agent inside to promote cancer cell destruction. The Figure shows what happens when two types of cells are treated with a 3H-labeled anti-cancer drug, paclitaxel.
Two additional drugs, imatinib and nilotinib, are evaluated for their ability to overcome the cancer cells’ ability to “pump out” the chemotherapeutic agent. An asterisk (*) indicates a statistically significant difference from the cells receiving paclitaxel alone. Do the additional drugs seem to the effective in over-coming the pump? Which set of graphs (A or B) best supports your answer? Explain your answer.
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Alleles at the P locus control seed color. Plants which are pp have white seeds, white flowers and no pigment in vegetative parts. Plants which are P_ have black seeds, purple flowers and may have varying degrees of pigment on stems and leaves. Seed color can be assessed, visually, based on if the seed is white or not white
A gene for mold resistance has been reported and we want to determine its inheritance and whether it is linked to P. For the purposes of this exercise, we will assume that resistance is controlled by a single locus M, and M_ plants are resistant and mm plants are susceptible. Resistance can be measured, under greenhouse conditions, 2 weeks after planting, by injecting each seedling with a spore suspension. After two weeks, the seedlings can be rated as resistant or susceptible, based on whether or not tissue is actively sporulating.
For this exercise we will use seed and data from the F10 generation of a recombinant inbred population produced using single seed…
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Alleles at the P locus control seed color. Plants which are pp have white seeds, white flowers and no pigment in vegetative parts. Plants which are P_ have black seeds, purple flowers and may have varying degrees of pigment on stems and leaves. Seed color can be assessed, visually, based on if the seed is white or not white
A gene for mold resistance has been reported and we want to determine its inheritance and whether it is linked to P. For the purposes of this exercise, we will assume that resistance is controlled by a single locus M, and M_ plants are resistant and mm plants are susceptible. Resistance can be measured, under greenhouse conditions, 2 weeks after planting, by injecting each seedling with a spore suspension. After two weeks, the seedlings can be rated as resistant or susceptible, based on whether or not tissue is actively sporulating.
For this exercise we will use seed and data from the F10 generation of a recombinant inbred population…
Chapter 5 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 5.1 - Describe the fluid mosaic model for membrane...Ch. 5.1 - Give two examples each of integral proteins and...Ch. 5.2 - What is the difference between passive and active...Ch. 5.2 - Prob. 2SBCh. 5.3 - Prob. 1SBCh. 5.3 - Prob. 2SBCh. 5.4 - Prob. 1SBCh. 5.4 - Prob. 2SBCh. 5.5 - Prob. 1SBCh. 5.5 - Prob. 2SB
Ch. 5 - In the fluid mosaic model: plasma membrane...Ch. 5 - Which of the following statements is false?...Ch. 5 - The freeze-fracture technique demonstrated: a....Ch. 5 - A characteristic of carrier molecules in a primary...Ch. 5 - A driving ion moving through a membrane channel in...Ch. 5 - Phagocytosis illustrates which phenomenon? a....Ch. 5 - Place in order the following events of...Ch. 5 - Prob. 8TYKCh. 5 - Which of the following statements is true for the...Ch. 5 - Using the principle of diffusion, a dialysis...Ch. 5 - Discuss Concepts The bacterium Vibrio cholera...Ch. 5 - Prob. 12TYKCh. 5 - Prob. 13TYKCh. 5 - Prob. 15TYKCh. 5 - Some cancer cells are insensitive to typical...Ch. 5 - Some cancer cells are insensitive to typical...
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