Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 5, Problem 14PDQ
In Drosophila, a cross was made between females–all expressing the three X-linked recessive traits scute bristles (sc), sable body (s), and vermilion eyes (v)–and wild-type males. In the F1, all females were wild type, while all males expressed all three mutant traits. The cross was carried to the F2 generation, and 1000 offspring were counted, with the results shown in the following table.
No determination of sex was made in the data.
- (a) Using proper nomenclature, determine the genotypes of the P1 and F1 parents.
- (b) Determine the sequence of the three genes and the map distances between them.
- (c) Are there more or fewer double crossovers than expected?
- (d) Calculate the coefficient of coincidence. Does it represent positive or negative interference?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Case Study—Ella
Review the case study and then answer Parts A through F.
Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch.
Categories of Sandwich Options (Top of the screen)
Breads
Spreads
Cheeses
Vegetables
Proteins
Specific food items to select
White Bread 6-inches
Honey Mustard
Provolone
LettuceTomatoBell Peppers
Turkey
Part A - Reading Nutrition Facts Panels for Total Kilocalories
How many total kilocalories are in Ella’s sandwich?
_____…
Chapter 5 Solutions
Concepts of Genetics (11th Edition)
Ch. 5 - In a family with one autistic child the risk for...Ch. 5 - Given that the prenatal test can provide only a...Ch. 5 - Prob. 3CSCh. 5 - Prob. 4CSCh. 5 - Consider two hypothetical recessive autosomal...Ch. 5 - With two pairs of genes involved (P/p and Z/z), a...Ch. 5 - In Drosophila, a heterozygous female for the...Ch. 5 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 5 - Review the Chapter Concepts list on page 94. Most...Ch. 5 - Describe the cytological observation that suggests...
Ch. 5 - Why does more crossing over occur between two...Ch. 5 - Explain why a 50 percent recovery of...Ch. 5 - Why are double-crossover events expected less...Ch. 5 - What is the proposed basis for positive...Ch. 5 - What two essential criteria must be met in order...Ch. 5 - The genes dumpy (dp), clot (cl), and apterous (ap)...Ch. 5 - Colored aleurone in the kernels of com is due to...Ch. 5 - In the cross shown here, involving two linked...Ch. 5 - In a series of two-point mapping crosses involving...Ch. 5 - Two different female Drosophila were isolated,...Ch. 5 - In Drosophila, a cross was made between femalesall...Ch. 5 - Another cross in Drosophila involved the...Ch. 5 - In Drosophila, Dichaete (D) is a mutation on...Ch. 5 - Drosophila females homozygous for the third...Ch. 5 - In Drosophila, two mutations, Stubble (Sb) and...Ch. 5 - If the cross described in Problem 18 were made,...Ch. 5 - Are mitotic recombinations and sister chromatid...Ch. 5 - What possible conclusions can be drawn from the...Ch. 5 - An organism of the genotype AaBbCc was testcrossed...Ch. 5 - Based on our discussion of the potential...Ch. 5 - Traditional gene mapping has been applied...Ch. 5 - DNA markers have greatly enhanced the mapping of...Ch. 5 - In a certain plant, fruit is either red or yellow,...Ch. 5 - Two plants in a cross were each heterozygous for...Ch. 5 - A number of humanmouse somatic cell hybrid clones...Ch. 5 - A female of genotype produces 100 meiotic tetrads....Ch. 5 - In laboratory class, a genetics student was...Ch. 5 - Drosophila melanogaster has one pair of sex...Ch. 5 - In Drosophila, a female fly is heterozygous for...Ch. 5 - The gene controlling the Xg blood group alleles...Ch. 5 - Prob. 34ESP
Additional Science Textbook Solutions
Find more solutions based on key concepts
Identify which of the following lac operon haploid genotypes transcribe operon genes induciblyand which transcr...
Genetic Analysis: An Integrated Approach (3rd Edition)
APPLY 1.2 Express the following quantities in scientific notation
using fundamental SI units of mass and lengt...
Chemistry (7th Edition)
There are 25 individuals in population 1, all with genotype AA, and there are 40 individuals in population 2, a...
Campbell Biology (11th Edition)
Which compound is more easily decarboxylated?
Organic Chemistry (8th Edition)
33. Consider the unbalanced chemical equation.
A chemistry student tries to balance the equation by placing th...
Introductory Chemistry (6th Edition)
What are the minimum and maximum ages of the island of Kauai? Minimum age: ______million yr Maximum age: ______...
Applications and Investigations in Earth Science (9th Edition)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- , if one of the archaeological specimens lacked the celiac disease-causing epitope, how could PCR be used to identify the allele in a contemporary germplasm collection of wild wheats, and to assist in transferring the allele to modern wheat varieties?arrow_forwardNow you will consider the composition of lipoproteins, including where they are synthesized, how they circulate, and where the various lipid and protein components are located within the lipoprotein molecule. Drag the appropriate labels to their respective targets.arrow_forwardThe Oregon Wolfe Barley mapping population is unique in having 12 easily-scored morphological markers, each showing monogenic inheritance. Do you consider these markers useful? Briefly defend your answer, pointing out advantages and disadvantages of morphological vs. molecular markers.arrow_forward
- Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions Calculate these : a) B1, b) B2, c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim g) k10 h) k12 i) k21 j) initial concentration (C0) k) central compartment volume (V1) l) steady-state volume (Vss) m) clearance (CL) AUC (0→10 min) using trapezoidal rule n) AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞) p) total AUC (using short cut method) q) volume from AUC (VAUC)arrow_forwardIn a population of Jackalopes (pictured below), horn length will vary between 0.5 and 2 feet, with the mean length somewhere around 1.05 feet. You pick Jackalopes that have horn lengths around 1.75 feet to breed as this appears to be the optimal length for battling other Jackalopes for food. After a round of breeding, you measure the offsprings' mean horn length is 1.67. What is the heritability of horns length (h2)? Is Jackalope horn length a heritable trait? (4 pts)? 12pt v R Paragraph V BIU A श्र > Barrow_forwardThere are many differences between DNA replication happening during mitosis in a Douglas fir tree growing in the Oregon Cascade Mountains and DNA replication happening during a PCR reaction in a forestry research lab at Oregon State University where the laboratory is amplifying a Simple Sequence Repeat. Complete the following table that compares the two DNA replication events in terms of the primers, the nucleotides, the polymerase, and the target sequence. Additionally, give a general value for the number of copies of the template DNA after one S phase in one cell and after the lab has completed the PCR reaction. Tree SSR Type your answer here: Primers Nucleotides Polymerase Target sequence Number of copiesarrow_forward
- Describe how insulin binding to its receptor induces glucose uptake in healthy individuals. Please specifyeach step in the cascade and use a diagram to illustrate the answer.arrow_forwardThere is a patient with breast cancer, after staining the breast tissue with H&E, state the molecular subtype of the tumour extracted. Results of H&E staining are down belowarrow_forwardBiopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions Calculate these : a) B1, b) B2, c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim g) k10 h) k12 i) k21 j) initial concentration (C0) k) central compartment volume (V1) l) steady-state volume (Vss) m) clearance (CL) AUC (0→10 min) using trapezoidal rule n) AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞) p) total AUC (using short cut method) q) volume from AUC (VAUC)arrow_forward
- Use the Henderson-Hasselbalch equation for a propanoic acid solution (CH₂CH₂CO₂H, pK₁ = 4.874) to calculate the quotient [A-]/[HA] at three different pH values. pH = 4.479 [A-] [HA] [A-] pH = 4.874 [HA] = pH = 5.220 [A-] = [HA]arrow_forwardIn order to establish the expiration date of perishable food, growth curve data must be collected. Once the microbial load is so high that it poses a hazard to human health, the food item is no longer considered safe (expired). Generally a load of x50,000 bacteria/gram is considered unsafe. Your task is to determine the microbial growth curves for MicroYo, a new brand of yogurt. The growth is determined by sampling the yogurt and growing the bacterial isolates in broth culture which is then serially diluted by a total of x10,000 and inoculated onto standard petri plates of nutrient agar. The following colony counts are measured: Time (days) MicroYo colony count# 1 1 4 1 12 2 16 20 4 7 What day should you recommend expiring the yogurt (the last possible date before the microbial load is unsafe). 12 4 20 16arrow_forward9. Chicken combs in chickens is an example where you see interactions between genes. See potential genotypes and phenotypes below. Which genotype, when mated to a rose comb chicken, will produce progeny that are 50% walnut comb and 50% pea comb? walnut (RRPP) walnut (RrPP) pea (rrPP) walnut (RRPP) walnut (RrPp) pea (rrPp) rose rose single (RRPP) (Rrpp) (rrpp)arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning
Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
Biology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage Learning
Concepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax College
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
Concepts of Biology
Biology
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:OpenStax College
How to solve genetics probability problems; Author: Shomu's Biology;https://www.youtube.com/watch?v=R0yjfb1ooUs;License: Standard YouTube License, CC-BY
Beyond Mendelian Genetics: Complex Patterns of Inheritance; Author: Professor Dave Explains;https://www.youtube.com/watch?v=-EmvmBuK-B8;License: Standard YouTube License, CC-BY