Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 5, Problem 13PDQ
Two different female Drosophila were isolated, each heterozygous for the autosomally linked genes b (black body), d (dachs tarsus), and c (curved wings). These genes are in the order d—b—c, with b being closer to d than to c. Shown here is the genotypic arrangement for each female along with the various gametes formed by both:
Identify which categories are noncrossovers (NCOs), single crossovers (SCOs), and double crossovers (DCOs) in each case. Then, indicate the relative frequency in which each will be produced.
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Students have asked these similar questions
The genotype of a Drosophila with a heterozygous translocation
between chromosome 2 and chromosome 3 is shown below, where bw =
brown eyes and e = ebony body:
bw+
bw
e
Assume there is no crossing over in the female and that alternate =
adjacent 1 = adjacent 2 disjunction. [Yes, these assumptions are incorrect, but
they make the problem much easier!] Two individuals of the above genotype,
i.e. both heterozygous for this 2;3 translocation and both heterozygous for bw
(on chromosome 2) and e (on chromosome 3) are crossed.
A (Only zygotes with balanced genomes will survive to adulthood.
What proportion of F1 zygotes have a balanced genome?
B. Draw the genotype(s) and state the phenotype(s) of the surviving
progeny you mentioned in part A above. For each different genotype/phenotype
indicate it's frequency among the surviving progeny.
In a cross in Drosophila, a female heterozygous for the autosomallylinked genes a, b, c, d, and e (abcde/ + + + + +) was testcrossedwith a male homozygous for all recessive alleles (abcde/abcde).Even though the distance between each of the loci was at least3 map units, only four phenotypes were recovered, yielding thefollowing data:
Phenotype No. of Flies+ + + + + 440a b c d e 460+ + + + e 48a b c d + 52 Total = 1000
Why are many expected crossover phenotypes missing? Can anyof these loci be mapped from the data given here? If so, determinemap distances.
A PORTION OF THE LINKAGE MAP OF CHROMOSOME
2 IN THE TOMATO IS ILLUSTRATED HERE.
ci (compound influorescence)
o (oblate)
- 15 CM
20 CM
p (peach)
THE OBLATE PHENOTYPE IS A FLATTENED FRUIT,
THE PEACH PHENOTYPE IS HAIRY FRUIT (LIKE A
PEACH), AND COMPOUND INFLORESCENCE MEANS
CLUSTERED FLOWERS.
IGNORE THE PEACH LOCUS. AMONG 1000 GAMETES
PRODUCED BY A PLANT OF GENOTYPE O CI /+ +,
WHAT TYPES OF GAMETES WOULD BE EXPECTED,
AND WHAT NUMBER WOULD BE EXPECTED OF EACH?
Chapter 5 Solutions
Concepts of Genetics (11th Edition)
Ch. 5 - In a family with one autistic child the risk for...Ch. 5 - Given that the prenatal test can provide only a...Ch. 5 - Prob. 3CSCh. 5 - Prob. 4CSCh. 5 - Consider two hypothetical recessive autosomal...Ch. 5 - With two pairs of genes involved (P/p and Z/z), a...Ch. 5 - In Drosophila, a heterozygous female for the...Ch. 5 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 5 - Review the Chapter Concepts list on page 94. Most...Ch. 5 - Describe the cytological observation that suggests...
Ch. 5 - Why does more crossing over occur between two...Ch. 5 - Explain why a 50 percent recovery of...Ch. 5 - Why are double-crossover events expected less...Ch. 5 - What is the proposed basis for positive...Ch. 5 - What two essential criteria must be met in order...Ch. 5 - The genes dumpy (dp), clot (cl), and apterous (ap)...Ch. 5 - Colored aleurone in the kernels of com is due to...Ch. 5 - In the cross shown here, involving two linked...Ch. 5 - In a series of two-point mapping crosses involving...Ch. 5 - Two different female Drosophila were isolated,...Ch. 5 - In Drosophila, a cross was made between femalesall...Ch. 5 - Another cross in Drosophila involved the...Ch. 5 - In Drosophila, Dichaete (D) is a mutation on...Ch. 5 - Drosophila females homozygous for the third...Ch. 5 - In Drosophila, two mutations, Stubble (Sb) and...Ch. 5 - If the cross described in Problem 18 were made,...Ch. 5 - Are mitotic recombinations and sister chromatid...Ch. 5 - What possible conclusions can be drawn from the...Ch. 5 - An organism of the genotype AaBbCc was testcrossed...Ch. 5 - Based on our discussion of the potential...Ch. 5 - Traditional gene mapping has been applied...Ch. 5 - DNA markers have greatly enhanced the mapping of...Ch. 5 - In a certain plant, fruit is either red or yellow,...Ch. 5 - Two plants in a cross were each heterozygous for...Ch. 5 - A number of humanmouse somatic cell hybrid clones...Ch. 5 - A female of genotype produces 100 meiotic tetrads....Ch. 5 - In laboratory class, a genetics student was...Ch. 5 - Drosophila melanogaster has one pair of sex...Ch. 5 - In Drosophila, a female fly is heterozygous for...Ch. 5 - The gene controlling the Xg blood group alleles...Ch. 5 - Prob. 34ESP
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- Black body (b) and purple eye (pr) are recessive autosomal mutations in Drosophila. Bridges are crossed b/b females with pr/pr males and in the F2 observed 684 wild type, 371 black-bodied, and 300 purple-eyed flies. Do these results indicate that the b and pr genes are closely linked? Explain. (Remember that there is no crossing-over in male Drosophila)..arrow_forwardConsider the following three autosomal recessive mutations in Drosophila:vestigial wings (v); wild type is long (v+)black body color (b); wildtype is gray (b+)plum eyes (p); wildtype is red (p+)A vestigal, gray, red female (homozygous for all three genes) is crossed with a long wing, black, plum male (homozygous for all three genes). The F1 female progeny are mated with triple homozygous recessive males. Here is the phenotypic data for the F2 progeny:vestigal; gray; red 580long wings; black; plum 592vestigal; black; red 45long; gray; plum 40vestigal; black; plum 89long; gray; red 94vestigal; gray; plum 3long; black; red 5A total of 1448 progeny were counted.Which one of the following values is the approximate distance between the plum eye color and black body color loci?arrow_forwardConsider the following two nonhomologous wildtype chromosomes, where letters or numbers represent genes, the "-" represents the centromere of each chromosome, and chromosomes are shown on separate lines. ABCDE-FGHIJK 123-45678 Identify the type of rearrangement shown in each of the following (A-C) and then identify whether it is balanced or unbalanced. Assume that the individual is diploid and heterozygous for the rearrangement. A. ABCDE-FGHIJKGH 123-45678 Rearrangement: [Select] • Balanced or Unbalanced: [Select] B. ABCDGF-EHIJK 123-45678 Rearrangement: [Select] Balanced or Unbalanced: [Select]arrow_forward
- In Drosophila melanogaster, ebony body (e) and rough eyes (ro) are encoded by autosomal recessive genes found on chromosome 3; they are separated by 20 m.u. The gene that encodes forked bristles (f) is X- linked recessive and assorts independently of e and ro. Give the phenotypes of progeny and their expected proportions when a female of each of the following genotypes is test-crossed with a male. ro a. ro ro b. - rotarrow_forwardMiniature wings (Xm) in Drosophila result from an X-linked allele that is recessive to the allele for long wings (X*). Give the genotypes of the parents in the following cross: Male parent Female parent Male offspring Female offspring 231 long, 250 miniature Long Long 560 long O male: Xm/Y and female X* /X* male: X* / Y and female Xm /x O male: X* /Y and female X* /X* male: Xm/Y and female Xm /x+arrow_forwardCinnabar eyes (cn) and reduced bristles (rd) are linked autosomal recesive characters in Drosophila fruit flies. A homozygous wild-type female was crossed to a reduced, cinnabar male, and the F1 females were then crossed with cinnabar reduced males to obtain the F2. Of the 200 F2 offspring obtained, 86 were wild type, 13 were cinnabar, 17 were reduced and 84 were reduced and cinnabar.. What is the map distance between the cn and rd alleles? 8,4 mu 15 mu 17 mu 30 mu 13 muarrow_forward
- Male Drosophila from a true-breeding wild-type stock were irradiated with X-rays and then mated with females from a true-breeding stock carrying the following recessive mutations on the X chromosome: yellow body (y), crossveinless wings (cv), cut wings (ct), singed bristles (sn), and miniature wings (m). These markers are known to map in the order: Recessive alleles: y, cv, ct, sn, m Dominant alleles: y+, cv+, ct+, sn+, m+ y-cv-ct-sn-m у CV ct sn m X-rays х х X ct sn CV у m y+ CV+ ct+ sn+ m+ х X ? Exceptional female: Most of the female progeny of this cross were phenotypically wild type, but one female exhibited ct and sn mutant characteristics. When this exceptional ct sn female was mated with a male from the true-breeding wild-type stock, twice as many females as males appeared among the progeny. a. What is the nature of the X-ray-induced mutation present in the exceptional female? b. Draw the X chromosomes present in the exceptional ct sn female as they would appear during pairing…arrow_forwardThe following is a linkage map of chromosome 5 for three genes in tomato: (see image) The cross between the triple heterozygote (Lf J W/ lf j w) and a triple homozygous recessive produced 500 progeny. Assume that there is no interference in the Lf-W region. Give the expected number of individuals for each of the following progeny types and show complete solutions.a. with crossover in the Lf-J and J-W regionsb. with crossover in the Lf-J regionc. with crossover in the J-W regiond. without crossover in the Lf-W regionarrow_forwardIn Drosophila, the genes st (scarlet eyes), ss (spineless bris- tles), and e (ebony body) are located on chromosome 3, with map positions as indicated: st SS e 44 58 70 Each of these mutations is recessive to its wild-type allele (st*, dark red eyes; ss*, smooth bristles; e*, gray body). Phenotypically wild-type females with the genotype st ss e*/st* st* ss+ e were crossed with triply recessive males. Predict the phenotypes of the progeny and the frequen- cies with which they will occur assuming (a) no interfer- ence and (b) complete interference.arrow_forward
- In Drosophila, the genes ct(cut wing margin), y (yellow body), and v (vermilion eye color) are X-linked. Females heterozygous for all three markers were mated with wildtype males and the following male progeny were obtained. As is conventional in Drosophila genetics, the wild-type allele of each gene is designated by a “+” sign in the appropriate column. Use the data to (A) create a genetic map of the genes, (B) calculate interference, and (C) interpret the value of interference. Show your work.arrow_forwardIn Drosophila,, the curled mutation (cu, chromosome 3, position 50.0) results in wings that curl up, while ebony (e, chromosome 3, position 70.7) results in a dark body. True breeding, wild type females are mated with true breeding males with curled wings and ebony bodies. Considering Drosophila notation, which of the following correctly diagrams the P1 cross? X X ++ e + + + O+ X + X + ■ + X + + + 3+ X X X X + + Y Y cu cu cu + cu cu J e e e e e (D e + cu cu (Darrow_forwardA standard three-point mapping is conducted for recessive mutations in autosomal genes purple eye (pr), curved wing ( c) and black body (b). Their wild type alleles are also used for genetic mapping. An F1 Drosophila female heterozygous for purple eye (pr), curved wing (c) and black (b) is crossed to a triply homozygous mutant male. The observed numbers and phenotypes of the offspring are as follows: 360 pr c b 380 pr+ c+ b+ 104 pr c+ b 96 pr+ c b+ 30 pr c b+ 20 pr+ c+ b 6 pr c+ b+ 4 pr+ c b PROVIDE THE FOLLOWING: A) State the order of genes on this chromosome. B) Calculate map distances between the gene pairs: pr-c, pr-b, c-b. Show calculations, state the number of map units and which gene pairs they refer to.arrow_forward
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