Human Anatomy & Physiology
1st Edition
ISBN: 9780805382952
Author: Erin C. Amerman
Publisher: PEARSON
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Chapter 4.8, Problem 1QC
How do regeneration and fibrosis differ?
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The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
There is currently a H5N1 cattle outbreak in North America.
According to the CDC on Feb 26*: "A multistate outbreak of HPAI A(H5N1) bird flu in dairy cows was first reported on March 25, 2024. This is the first time that these bird flu viruses had been found in cows. In the United States, since 2022, USDA has reported HPAI A(H5N1) virus detections in more than 200 mammals."
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You have a bacterial strain with the CMU operon:
a) As shown in the image below, the cmu operon encodes a peptide (Pep1), as well as a
kinase and regulator corresponding to a two-component system. The cmu operon is
activated when Pep 1 is added to the growth media.
Pep1 is a peptide that when added extracellularly leads to activation of the Cmu operon.
Pep1 cmu-kinase cmu-regulator
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Chapter 4 Solutions
Human Anatomy & Physiology
Ch. 4.1 - What are the four types of tissues, and what are...Ch. 4.1 - What are the two major components of the ECM, and...Ch. 4.1 - What are the three types of protein fibers?...Ch. 4.1 - Prob. 4QCCh. 4.2 - Why is living epithelial tissue limited to a...Ch. 4.2 - Where is the ECM of epithelial tissue located, and...Ch. 4.2 - What are the three basic shapes of epithelial...Ch. 4.2 - What are the differences between simple,...Ch. 4.2 - Prob. 5QCCh. 4.2 - How do exocrine and endocrine glands differ?
Ch. 4.2 - Compare and contrast merocrine and holocrine...Ch. 4.3 - 1. What are the types of cells of connective...Ch. 4.3 - What is the primary component in: a. loose...Ch. 4.3 - What are the primary differences between brown and...Ch. 4.3 - How do the three types of cartilage differ?Ch. 4.3 - How do bone and blood differ from other connective...Ch. 4.4 - What are the two forms of muscle cells, and how do...Ch. 4.4 - Compare and contrast the three types of muscle...Ch. 4.5 - What are the two main cell types in nervous...Ch. 4.5 - 2. What are the three parts of a neuron, and what...Ch. 4.7 - Where are serous and synovial membranes located,...Ch. 4.7 - 2. Where are mucous membranes located, and what...Ch. 4.7 - 3. What is the cutaneous membrane? What is its...Ch. 4.8 - How do regeneration and fibrosis differ?Ch. 4.8 - Which tissues generally heal by regeneration?...Ch. 4.8 - Which factors influence the ability of a tissue to...Ch. 4 - 1 Which of the following best describes the...Ch. 4 - 2. State whether each of the following describes...Ch. 4 - Describe the roles of each of the following...Ch. 4 - Prob. 4CYRCh. 4 - Mark the following statements as true or false. If...Ch. 4 - 6. Match each type of epithelium with its correct...Ch. 4 - Compare and contrast the following pairs of terms:...Ch. 4 - Explain how connective tissues differ from...Ch. 4 - 9. Mark the following statements as true or...Ch. 4 - 10. Match the following types of connective...Ch. 4 - Which of the following statements about muscle...Ch. 4 - 12. Fill in the blanks: _____are the cells of...Ch. 4 - Prob. 13CYRCh. 4 - Which tissues undergo regeneration? Which tissues...Ch. 4 - 1. If you were to cut through epithelial tissue...Ch. 4 - Prob. 2CYUCh. 4 - Prob. 3CYUCh. 4 - The disease pemphigus vulgaris involves a patients...Ch. 4 - Prob. 2AYKACh. 4 - 3. In the disease pulmonary fibrosis, elastic...Ch. 4 - Imagine that a disease turns the simple epithelia...Ch. 4 - Epithelial cells of the kidneys have pumps that...Ch. 4 - Explain why it would be difficult for a mature...Ch. 4 - 7. Predict which organelles are likely to be...
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- You have identified a new species of a Gram-positive bacteria. You would like to screen their genome for all proteins that are covalently linked to the cell wall. You have annotated the genome, so that you identified all the promoters, operons, and genes sequences within the operons. Using these features, what would you screen for to identify a set of candidates for proteins covalently linked to the bacterial cell wall.arrow_forwardBelow is a diagram from a genomic locus of a bacterial genome. Each arrow represents a coding region, and the arrowheads indicate its orientation in the genome. The numbers are randomly assigned. Draw the following features on the diagram, and explain your rationale for each feature: 10 12 合會會會會長 6 a) Expected transcriptions, based on known properties of bacterial genes and operons. How many proteins are encoded in each of the transcripts? b) Location of promoters (include rationale) c) Location of transcriptional terminators (include rationale) d) Locations of Shine-Dalgarno sequences (include rationale)arrow_forwardSample excuse letter in school class for the reasons of headaches and dysmenorrhea caused by menstrual cyclearrow_forward
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