CAMPBELL BIOLOGY,VOL.II >CUSTOM<
17th Edition
ISBN: 9781323803677
Author: Urry
Publisher: PEARSON
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Chapter 47, Problem 47.3CR
Suppose you found two classes of mouse mutations, one that .affected limb development only and one that affected both limb and kidney development. Which class would be more likely to alter the function of monocilia? Explain.
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Suppose you found two classes of mouse mutations, one that affectedlimb development only and one that affected both limb and kidneydevelopment. Which class would be more likely to alter the functionof monocilia? Explain.
You are studying a mutation in mice, which acts dominantly. Mice that have only one copy of the allele carrying this mutation have a kinky tail phenotype. You identify the gene that the mutation affects and find that the codon that encodes the second amino acid in the predicted protein has been mutated to a stop codon. Would you characterize this mutation as a loss-of-function or a gain-of-function and what specific subtype (hypermorphic, antimorphic, etc. ) within these categories? Explain your reasoning.”
given a situation in which you manipulated a zebrafish embryo by injecting high levels of retinoic acid so that no anterior genes will be expressed. Surprisingly, after embryonic development, you are still able to observed the presence of anterior structures. What could explain this observation? What changes in your experiment would you make to achieve your objective?
Chapter 47 Solutions
CAMPBELL BIOLOGY,VOL.II >CUSTOM<
Ch. 47.1 - How does the fertilization envelope form in sea...Ch. 47.1 - Prob. 2CCCh. 47.1 - MAKE CONNECTIONS Review Figure 12.16 on cell...Ch. 47.2 - In the frog embryo, convergent extension elongates...Ch. 47.2 - WHAT IF? Predict what would happen if Ca2+ was...Ch. 47.2 - MAKE CONNECTIONS Unlike some other types of birth...Ch. 47.3 - Prob. 1CCCh. 47.3 - Prob. 2CCCh. 47.3 - Prob. 3CCCh. 47.3 - Prob. 4CC
Ch. 47 - What cell-surface event would likely fail if a...Ch. 47 - What are some functions of apoptosis in...Ch. 47 - Suppose you found two classes of mouse mutations,...Ch. 47 - Prob. 1TYUCh. 47 - Which of the following is common to the...Ch. 47 - The archenteron develops into a. the mesoderm. b....Ch. 47 - What structural adaptation in chickens allows them...Ch. 47 - Prob. 5TYUCh. 47 - In humans, identical twins are possible because a....Ch. 47 - Cells transplanted from the neural tube of a frog...Ch. 47 - DRAW IT Each blue circle in the figure below...Ch. 47 - EVOLUTION CONNECTION Evolution in insects and...Ch. 47 - Prob. 10TYUCh. 47 - Prob. 11TYUCh. 47 - Prob. 12TYUCh. 47 - SYNTHESIZE YOUR KNOWLEDGE Occasionally, two-headed...
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- Synpolydactyly is an abnormality characterized by webbing between partially or completely duplicated fingers or toes (Figure 18.15). The same mutations that cause the human phenotype give rise to a similar phenotype in mice. In what family of genes do you think these mutations occur?arrow_forwardCystic Fibrosis is a genetically heritable disease caused by the loss of the chloride channel, CFTR. Studies of this gene have found that the Gene includes 250,000bp in the DNA. Scientists found that the mRNA had 6,500 nucleotides, and the final protein had 1480 amino acids. How much of the mRNA is untranslated? How much of the RNA that is produced does not leave the nucleus? One of the mutations that results in a disease phenotype can be easily identified because the mutation results in a much longer mRNA then normal. Where would you look for this mutation? What might this mutation have affected?arrow_forwardIn the nematode C. elegans, some worms have blisteredcuticles due to a recessive mutation in one of the bligenes. Someone studying a suppressor mutation thatsuppressed bli-3 mutations wanted to know if it wouldalso suppress mutations in bli-4. They had a strain thatwas homozygous for this recessive suppressor mutation,and its phenotype was wild type.a. How would they determine whether this recessivesuppressor mutation would suppress mutations in bli-4?In other words, what is the genotype of the wormsrequired to answer the question?b. What cross(es) would they do to make these worms?c. What results would they expect in the F2 if(1) it did act as a suppressor of bli-4?(2) it did not act as a suppressor of bli-4?arrow_forward
- Proteins A,B,C, and D in the diagram are encoded by different genes and interact with each other. Imagine that a mutation in the gene for protein A changes one of the charged amino acid in the red circle area from positive to negative charge (blue arrow). this mutation results in a mutant phenotype. Assume a mutation in the gene for protein B occurs and the double mutants have a phenotype that is almost wild type. How would you best describe the mutation in gene B? Protein C Proten A Protein B Protein B Wild type Mutation in the gene for protein Aarrow_forwardGiven the following schematic for a gene and its associated regulatory regions, answer the following questions by placing the correct letter in the provided blanks please put in the correct letter for the questions What region would provide cell type-specific expression of genes? region What site would significantly increase gene expression rates? = region What region or regions of this gene’s coding sequence are expressed as amino acids = regionarrow_forwardThe figure below represents a cell undergoing gene expression. Use the figure to answer the questions that follow (a - e). a. What is indicated by label (2) in the figure above? b. What is indicated by label (3) in the figure above? c. What happens to the part labelled (3) and what complex makes it happen? d. Which amino acid is represented by (6)? e. Give the one anticodon in the 5' to 3' direction that will recognize all the codons for this amino acid in (c)arrow_forward
- The homeotic mutation Antennapedia causes mutant Drosophila to have legs in place of antennae and is a dominant gain-of-function mutation. List all the properties of such mutations. How does the Antennapedia gene change antennae into legs?arrow_forwardYou are interested in the effects of mutations on the expression of a human protein- encoding gene expressed in skin cells. The gene has one intron that is 450 nucleotides long. After this intron is removed from the pre-mRNA, the mRNA transcript is 1100 nucleotides in length. Diploid somatic cells have two copies of this gene. Predict the size and amount of mRNA from the cytosol of skin cells, which were obtained from the following individuals: • Individual 1: Normal individual with no mutations in this gene. • Individual 2: Homozygous for a deletion that removes the -10 to -100 region of the gene that encodes this mRNA. • Individual 3: Heterozygous in which one gene is normal and the other gene has a deletion that removes the -10 to -100 region. • Individual 4: Homozygous for a five-nucleotide deletion in the intron that removes the GT sequence at the 5' splice site. Explain your answers.arrow_forwardMany aspects of gene function can be nicely explained with the one-gene-one-enzyme hypothesis, which states that a gene controls the production of an enzyme. Which of the following findings about gene expression, though, requires an expansion of this simple concept? Choose an answer below: Non-enzyme proteins are made from genes too. Some genes code for RNA molecules only. Enzymes composed of different polypeptides are coded for by more than one gene. a and c, but not b a, b, and carrow_forward
- Many aspects of gene function can be nicely explained with the one- gene-one-enzyme hypothesis, which states that a gene controls the production of an enzyme. Which of the following findings about gene expression, though, requires an expansion of this simple concept? Non-enzyme proteins are made from genes too. Some genes code for RNA molecules only. Enzymes composed of different polypeptides are coded for by more than one gene. a and c, but not b a, b, and carrow_forwardFigure shows a part of the sequence alignment of human and whale myoglobin proteins. Please explain the difference between green- and yellow-colored mutations. Which mutations have higher probability to change the function of protein, why?arrow_forwardWhich of the following scenario will result in greater consequences in terms of gene expression? insertion or deletion of one nucleotide insertion or deletion of three nucleotides Explain why.arrow_forward
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY