BIOLOGY-TEXT
5th Edition
ISBN: 9781260169621
Author: BROOKER
Publisher: MCG
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Chapter 4.7, Problem 2CC
Summary Introduction
To determine: The consequence of a chaperone protein not binding to a protein before being imported into the mitochondrial matrix.
Introduction: A eukaryotic cell consists of many cell organelles enclosed within a plasma membrane. Mitochondria and chloroplast are considered as semi-autonomous organelles because they possess the ability to grow and divide due to the presence of their own DNA. However, they are semi-autonomous as they depend on other parts of the cell, such as cytosol to import their internal components.
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How are proteins normally transported into the mitochondrial matrix, if they were originally synthesized on ribosomes present in the cytosol (not on the rough endoplasmic reticulum)?
they are packaged into vesicles with v-SNARES for fusion with their target organelles
they can pass freely through large pores in the inner mitochondrial membrane
they are secreted by the golgi, captured by receptors, and absorbed by endosomes
they must pass through the nuclear envelope by means of nuclear pores
they are unfolded in the translocation channel, then refolded by chaperones
How do proteins targeted to the mitochondrial matrix reach their destination?
What is the order of events for importing a protein to mitochondria?
Chapter 4 Solutions
BIOLOGY-TEXT
Ch. 4.1 - What properties of deep-sea vents made them...Ch. 4.1 - Which protobiont seems most similar to todays...Ch. 4.1 - Core Skill: Connections Look back at Figure 3.11....Ch. 4.1 - Prob. 3CCCh. 4.2 - Prob. 1CCCh. 4.2 - Prob. 2CCCh. 4.3 - Prob. 1CSCh. 4.3 - Prob. 1CCCh. 4.3 - Prob. 2CSCh. 4.4 - Prob. 1CS
Ch. 4.4 - Describe the type of movements that occur between...Ch. 4.4 - Prob. 2CSCh. 4.5 - Prob. 1CCCh. 4.5 - Prob. 1CSCh. 4.5 - If we consider the Golgi apparatus as three...Ch. 4.5 - The Nucleus and Endomembrane System Experimental...Ch. 4.5 - Prob. 2EQCh. 4.5 - Prob. 3EQCh. 4.5 - Prob. 3CCCh. 4.6 - Prob. 1CCCh. 4.6 - Core Skill: Connections Look ahead to Figure...Ch. 4.7 - Prob. 1CCCh. 4.7 - Prob. 2CCCh. 4 - The cell theory states that a. all living things...Ch. 4 - Prob. 2TYCh. 4 - Prob. 3TYCh. 4 - Prob. 4TYCh. 4 - Each of the following is part of the endomembrane...Ch. 4 - Prob. 6TYCh. 4 - Functions of the smooth endoplasmic reticulum...Ch. 4 - Prob. 8TYCh. 4 - Prob. 9TYCh. 4 - Which of the following observations would not be...Ch. 4 - What are the four stages that led to the origin of...Ch. 4 - Explain how motor proteins and cytoskeletal...Ch. 4 - Prob. 3CQCh. 4 - Discuss the roles of the genome and proteome in...Ch. 4 - Prob. 2COQ
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- Only 37 of the proteins in mitochondria are encoded by the mitochondrial DNA. The other proteins are encoded in nuclear DNA, then translated and transported to the mitochondria. Describe one unique feature of protein transport across mitochondrial membranes.arrow_forwardPredict the outcome of a mitochondrial membrane that is more permeable to hydrogen ions than normal. answer choices A.) Increased levels of inorganic phosphate in the mitochondrial matrix B.) Reduced formation of water C.) Reduced activity of electron transport chain D.) Increased activity of ATP synthasearrow_forwardExplain briefly how proteins synthesized in the cytosol get into mitochondrial matrix.arrow_forward
- 1) Which of the following contains all of the information required to target a precursor protein from the cytosol to the mitochondrial matrix? a. N-terminal uptake-targeting sequence b. C-terminal uptake-targeting sequence c. post-translational organelle d. translocon e. None of the above 2) In the absence of targeting information, what is the default location of proteins synthesized on cytosolic ribosomes? a. Golgi apparatus b. ER lumun c. Cytosol d. Cell plasma membrane e. ER membranearrow_forwardIn human cells, where does fatty acid elongation (that is, beyond the C16:0 normally produced by fatty acid synthase) occur? a)On the outer (cytosolic) face of the outer mitochondrial membrane b)On the outer (cytosolic) face of the endoplasmic reticulum membrane c)Free in the cytosol d)In the mitochondrial matrixarrow_forwardIn the 1930’s DNP was given to people to lose weight. DNP makes the mitochondrial membrane leaky to hydrogen ions. Why might this cause one to lose weight? Why would this cause death? How is this similar or different to cyanide which binds to complex IV in the mitochondria?arrow_forward
- Which of the following allow for the transport of protons into the mitochondrial matrix? a) Pyruvate transporter b) Phosphate translocase c) ATP synthase d) A and C e) All of the above f) None of the abovearrow_forwardDescribe the source or sources of energy needed for unidirectional translocation across the membrane in (a) cotranslational translocation into the endoplasmic reticulum (ER); (b) post-translational translocation into the ER; (c) translocation into the mitochondrial matrix.arrow_forwardExplain briefly how a protein made in the nucleus gets to its final destination in the Mitochondrial Inner Membrane.arrow_forward
- When NADH and FADH2 are oxidized by the proteins in the electron transport chain, A) protons are pumped into the mitochondrial intermembrane space. B) hydrogen ions are pumped into the mitochondrial matrix. C) protons are pumped into the mitochondrial matrix. D) electrons are pumped into the cytoplasm.arrow_forwardHow is the function of the thylakoid membrane similar to that of the inner mitochondrial membrane?arrow_forwardWhat are mitochondria? What is their structure, function, and where did they come from during evolution?arrow_forward
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