To determine: The effects of significant reduction of macrophages in the body.
Introduction: A complex network of cells, tissues, and organs that work collectively to protect the body and fight against the pathogens or foreign substances is called the immune system. Immune cells are the cells that actively participate in the defense mechanism initiated by the immune systems. One such major type of immune cells is lymphocytes.
To determine: Whether a significant decrease of macrophage or of memory B cells would have a greater effect on the immune system.
Introduction: A complex network of cells, tissues, and organs that work collectively to protect the body and fight against the pathogens or foreign substances is called the immune system. Immune cells are the cells that actively participate in the defense mechanism initiated by the immune systems. One such major type of immune cells is lymphocytes.
Want to see the full answer?
Check out a sample textbook solutionChapter 45 Solutions
Mindtap Biology, 1 Term (6 Months) Printed Access Card For Solomon/martin/martin/berg's Biology, 11th
- In an immune response, what is the main function of the circulatory system? to produce inflammation and activate B cells to send chemical signals and transport immune cells to stimulate infected cells and release interferons to trap pathogens and attract phagocytesarrow_forwardExplain the following concept in human physiology and cite clinical instances, where applicable A. Immunological tolerance B. Hypersensitive reactionarrow_forwardExplain why each choice (a-d) is correct or incorrect. Which of the following examples below describes an autoimmune disease? a. Infection and death of T helper cells by a virus, resulting in a loss of adaptive immunity b. Release of bacterial endotoxins that block acetylcholine release result in muscle paralysis. c. Antibody binding to acetylcholine receptors of the motor end plate resulting in muscle weakness. d. Uncontrolled cell division resulting in cell surface abnormalities recognized by NK cells.arrow_forward
- Explain why it would be important for a person living with AIDS or for someone who has recently received radiation therapy to avoid people with a cough or cold?arrow_forwardJohn frequently encountered bacterial infections. Tests for immune cells showed the presence of mature B and T cells in his blood. Extensive analysis showed that John was lacking a gene responsible for a protein for complement factor C5. 1. Which immune response will be inhibited because of C5 deficiency? 2. How would it affect John’s ability to fight infections? Specifically what type of infections is he likely to have difficulty fighting? Please explain in detail. 3. What would have been the implications if he was lacking the C3 complement component?arrow_forwardVaccines are used to train our adaptive immune system. With live-attenuated vaccines, a weakened form of the pathogen is injected. Describe the steps of an adaptive immune response to this type of vaccine (1 sentence per step). Explain how the immune system of a person who received the vaccine would respond to a later exposure to the pathogen (1-2 sentences).arrow_forward
- Describe neutrophils and NK cells, giving one example of how each cell type destroys pathogens that have invaded your body. Why are they both part of the “innate” immune system?arrow_forwardUse to answer: In 1984, Robert Gallo and Luc Montagnier independently identified what is known today as HIV (human immunodeficiency virus). Worldwide, 17 million people suffer from HIV, which is a virus that attacks human T lymphocytes. The T lymphocytes, a crucial part of the immune system, mature in the thymus. As a result of HIV, B cell lymphocytes also decrease in number . Most HIV patients die because of other diseases like tuberculosis and cancer. Once an infected individual's lymphocytes count reaches less than 200 per cubic millimeter of blood (normal is 500-1100 T cells/mm^ 3 ) , susceptibility to disease increases, and levels below 10 can be fatal. A) How would a decrease in the thymus T cell lymphocytes cause an increase in susceptibility of disease? B) Identify the 4 types of Tlymphocytes that mature in the thymus, including their role in the immune response: C) A decrease in B cell lymphocytes would affect the immune system in what way ?arrow_forwardFor an autoimmune disease to occur, lymphocytes do not learn how to recognize foreign pathogens as dangerous and self-antigens as safe. What is the second thing that needs to happen specifically with lymphocytes to have an autoimmune disease? O a. Malfunctioning lymphocytes attach to macrophages O b. Malfunctioning lymphocytes are not destroyed by the body O c. Malfunctioning lymphocytes prevent normal lymphocytes from reproducing O d. Malfunctioning lymphocytes trigger the complement system to initiate an immune responsearrow_forward
- Considering the mechanisms of innate immunity, which of the following pairs is accurately matched? Select one: a. Neutrophils – increase in number in response to bacterial infections b. Complement – slow the spread of viral infections c. Interferons – assist antibodies in the destruction of pathogens d. Eosinophil – recognize abnormal cells, such as cancer cellsarrow_forwardWhat is the role of T cell, B cells, and Natural killer cells in the function of the Immune system?arrow_forwardIndicate to which branch(es) of the immune system the following statements apply, using H for the humoral branch and CM for the cell-mediated branch. Some statements may apply to both branches (B). a. Involves B cells b. Involves T cells c. Responds to extracellular bacterial infection d. Involves secreted antibody e. Kills virus-infected self cellsarrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education