Biological Science
Biological Science
5th Edition
ISBN: 9780321743671
Author: Scott Freeman
Publisher: PEARSON
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Chapter 45, Problem 10TYU
Summary Introduction

To review:

The reflection of all the parameters of Fick’s law in the structure of the mammalian lungs.

Introduction:

Fick’s law of diffusion regarding the diffusion of gases was given by Adolf Fick. The law states that the rate of diffusion depends on different parameters, namely, diffusion constant (k), which depends on the gas solubility and temperature, the difference in the partial pressure of gas across the gas exchange surface (P2P1), available surface area for diffusion (A), and the thickness of diffusion barrier (D). The equation derived by Adolf Fick to determine the rate of diffusion of gases was

Rate of diffusion=k×A×(P2P1)D

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With reference to their absorption spectra of the oxy haemoglobin intact line) and deoxyhemoglobin (broken line) shown in Figure 2 below, how would you best explain the reason why there are differences in the major peaks of the spectra? Figure 2. SPECTRA OF OXYGENATED AND DEOXYGENATED HAEMOGLOBIN OBTAINED WITH THE RECORDING SPECTROPHOTOMETER 1.4 Abs < 0.8 06 0.4 400 420 440 460 480 500 520 540 560 580 600 nm 1. The difference in the spectra is due to a pH change in the deoxy-haemoglobin due to uptake of CO2- 2. There is more oxygen-carrying plasma in the oxy-haemoglobin sample. 3. The change in Mr due to oxygen binding causes the oxy haemoglobin to have a higher absorbance peak. 4. Oxy-haemoglobin is contaminated by carbaminohemoglobin, and therefore has a higher absorbance peak 5. Oxy-haemoglobin absorbs more light of blue wavelengths and less of red wavelengths than deoxy-haemoglobin
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