Chapter 44.2, Problem 1R

Summary Introduction

To review:

The reason due to, which the Goldman equation is able to produce a more reliable calculation of resting membrane potential as compared to the Nernst equation.

Introduction:

The resting membrane potential is maintained by the efflux of potassium ions (K⁺) and the influx of the sodium ions (Na⁺) inside the cell with the help of the sodium-potassium pump. The concentration of the K⁺ across the membrane is calculated once equilibrium is established between them. This is calculated by using Nernst equation. The Goldman equation, however, also involves the following:

All ions, which are capable of crossing the membrane.

The relative permeability provided by the membrane to all the ions.