BIOLOGY(LL)-W/ACCESS CODE >CUSTOM<
12th Edition
ISBN: 9781264058167
Author: Raven
Publisher: MCG CUSTOM
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Chapter 44, Problem 2S
Suppose that two different organs, such as the liver and heart, are sensitive to a particular hormone (such as epinephrine). The cells in both organs have identical receptors for the hormone, and hormone-receptor binding produces the same intracellular second messenger in both organs. However, the hormone produces different effects in the two organs. Explain how this can happen.
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Suppose that two different organs, such as the liver and heart, are sensitive to a particular hormone (such as epinephrine). The cells in both organs have identical receptors for the hormone, and hormone-receptor binding produces the same intracellular second messenger in both organs. However, the hormone produces different effects in the two organs. Explain how this can happen.
Visit this link (http://openstaxcollege.org/l/hormonebind) to watch an animation of the events thatoccur when a hormone binds to a cell membrane receptor.What is the secondary messenger made by adenylyl cyclaseduring the activation of liver cells by epinephrine?
Suppose you are studying a cell’s response to a particularhormone. You observe that the cell produces the same response to thehormone whether or not the cell is treated with a chemical that blockstranscription. What can you surmise about the hormone and its receptor?
Chapter 44 Solutions
BIOLOGY(LL)-W/ACCESS CODE >CUSTOM<
Ch. 44.1 - Prob. 1LOCh. 44.1 - Prob. 2LOCh. 44.1 - Prob. 3LOCh. 44.2 - Prob. 1LOCh. 44.2 - Prob. 2LOCh. 44.2 - Prob. 3LOCh. 44.3 - Prob. 1LOCh. 44.3 - Describe the connections between the hypothalamus,...Ch. 44.3 - Prob. 3LOCh. 44.4 - Prob. 1LO
Ch. 44.4 - Describe the components of Ca2+ homeostasis.Ch. 44.4 - Prob. 3LOCh. 44.5 - Prob. 1LOCh. 44.5 - Prob. 2LOCh. 44.5 - Prob. 3LOCh. 44 - Prob. 1DACh. 44 - Prob. 1IQCh. 44 - Which of the following best describes hormones? a....Ch. 44 - Steroid hormones a. can diffuse through the...Ch. 44 - Second messengers are activated in response to a....Ch. 44 - Which of the following is true about lipophilic...Ch. 44 - An organ is classified as part of the endocrine...Ch. 44 - Hormones released from the pituitary gland have...Ch. 44 - Prob. 7UCh. 44 - You think one of your teammates is using anabolic...Ch. 44 - Your Uncle Sal likes to party. When he goes out...Ch. 44 - Prob. 3ACh. 44 - Prob. 4ACh. 44 - Prob. 5ACh. 44 - You experience a longer period than normal between...Ch. 44 - Mild vitamin D deficiency can lead to...Ch. 44 - How can blocking hormone production decrease...Ch. 44 - Suppose that two different organs, such as the...Ch. 44 - Many physiological parameters, such as blood Ca2+...
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- Overexpression of this receptor in the cells of the adrenal gland causes Cushing's syndrome, a disease caused by the overproduction of cortisol. One strategy that scientists have employed to treat this disease is the use of small molecules that bind to, but do not activate, MC2R. This type of molecule is generically referred to as an antagonist. How can an antagonist bind to the same receptor as ACTH but not activate it? O a. The antagonist can bind covalently while ACTH binds non-covalently O b. The antagonist is only partially complimentary to the binding pocket of MC2R O The antagonist binds to ACTH and blocks it from binding to the receptor properly O d. The antagonist is the exact same structure as ACTH but since it is synthetic it doesn't work One cause of Cushing's syndrome is the inappropriate production of GPCRS in the adrenal gland that are not normally present in those cells. When these receptors are activated they result in the production of cortisol. Which statement about…arrow_forwardWhich statement correctly identifies how a lipid-soluble hormone that diffuses from the blood and through the interstitial fluid identifies which cells in the tissue to act upon? O The cell closest to the diffusion site. O The presence of a receptor located in the cytoplasm or nucleus specific to the hormone in cells. O The presence of a receptor embedded in the plasma membrane of target cells. O The presence of a channel protein embedded in the plasma membrane for the lipid-soluble hormone to diffuse through. Save for Later 80 F3 F4 F5 F6 8 F7 Attempts: 0 of 3 used F8 F9 Submit Answer F10arrow_forwardIf a hormone interacts with a membrane-bound receptor, then the cell’s DNA will be stimulated to synthesize and secrete a protein. True or False?arrow_forward
- Trace in a stepwise manner the signaling pathway that involves a g-protein receptor leading to the release of intracellular calcium. Specify what class of hormones would be involved in this pathway.arrow_forwardwhich of the following statements best characterizes the hormone-receptor interaction? a. receptors can have different affinities for multiple ligands b. each hormone will only interact with one type of receptor c. the hormone-receptor contact is generally irreversible d. most cells express receptors for all hormonearrow_forwardSuppose that the circulating concentration of hor-mone is 10–10 M and the Kd for binding to its receptor is 10–8M. What fraction of the receptors will have hormone bound?If a meaningful physiological response occurs when 50% ofthe receptors have bound a hormone molecule, how muchwill the concentration of hormone have to rise to elicit aresponse? The fraction of receptors (R) bound to hormone(H) to form a receptor–hormone complex (R–H) is [R–H]/([R] + [R–H]) = [R–H]/[R]TOT = [H]/([H] + Kd).arrow_forward
- What cellular response (up-regulation or down-regulation) would you predict occurs in response to high doses of a drug that binds to a specific hormone receptor? Will more or less of the drug be required for the same response over time? Explain.arrow_forwardExplain how the chemical nature of the plasma membrane acts on the two chemical categories of hormones, and thus the type of response each hormone can induce in a target cell. Be sure to thoroughly describe the two types of cellular responses.arrow_forwardDuring a sympathetic nervous system response to an event, your heart rate increases, indicating the part of the heart responsible for controlling heart rate (the sinoatrial node) is innervated by sympathetic nerves. The SA node is also responsive to epinephrine,a hormone secreted by the adrenal medulla. Explain why the onset of the effect of the hormone is so much slower than the onset of the effect from sympathetic nerve stimulation and yet the effect of the hormone lasts much longer than the effect of nerve stimulation.arrow_forward
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