The spontaneity of any reaction can be determined by looking at the value of Gibbs free energychange (delta G ). The overall negative value indicates that the reaction is spontaneous whereas a positive value indicates that the reaction cannot occur in those conditions. Non- spontaneous reactions can be made to occur by coupling them with other reactions such as ATP hydrolysis(delta G = –30.5 kilojoules per mole) so that the overall value of Gibbs free energy turns out to be negative.

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Chapter 4, Problem 6RQ

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The spontaneity of any reaction can be determined by looking at the value of Gibbs free energychange (delta G). The overall negative value indicates that the reaction is spontaneous whereas a positive value indicates that the reaction cannot occur in those conditions. Non- spontaneous reactions can be made to occur by coupling them with other reactions such as ATP hydrolysis(delta G = –30.5 kilojoules per mole) so that the overall value of Gibbs free energy turns out to be negative.

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