Abnormal Motor Proteins Cause Kartagener Syndrome An abnormal form of a motor protein called dynein causes Kartagener syndrome, a genetic disorder characterized by chronic sinus and lung infections. Biofilms form in the thick mucus that collects in the airways, and the resulting bacterial activities and inflammation damage tissues. Affected men can produce sperm but are infertile. Some have become fathers after a doctor injects their sperm cells directly into eggs. Review FIGURE 4.21 and FIQURE 4.24, then explain how abnormal dynein could cause the observed effects. FIGURE 4.24 Cross-section of the flagellum of a sperm cell from A a human male affected by Kartagener syndrome and B an unaffected male.

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Answer 1

Textbook Question

Chapter 4, Problem 1DAA

Abnormal Motor Proteins Cause Kartagener Syndrome An abnormal form of a motor protein called dynein causes Kartagener syndrome, a genetic disorder characterized by chronic sinus and lung infections. Biofilms form in the thick mucus that collects in the airways, and the resulting bacterial activities and inflammation damage tissues.

Affected men can produce sperm but are infertile. Some have become fathers after a doctor injects their sperm cells directly into eggs. Review FIGURE 4.21 and FIQURE 4.24, then explain how abnormal dynein could cause the observed effects.

Chapter 4, Problem 1DAA, Abnormal Motor Proteins Cause Kartagener Syndrome An abnormal form of a motor protein called dynein

FIGURE 4.24 Cross-section of the flagellum of a sperm cell from A a human male affected by Kartagener syndrome and B an unaffected male.

Expert Solution & Answer

Summary Introduction

To explain: How abnormal dynein could cause Kartagener syndrome and male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in dynein (a component of cilia) arms. This results in the abnormal morphology of sperm tails and bronchial cilia.

Explanation of Solution

Refer to Fig. 4.20, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in dynein arms causes Kartagener syndrome. Refer to Fig. 4.24, “Cross-section of a sperm cell from A. a human male affected by Kartagener syndrome and B. an unaffected male” in the textbook. The lack of dynein arms results in the abnormal morphology of sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because defected dynein would affect the movement of flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

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Answer 2

Textbook Question

Chapter 4, Problem 1DAA

Abnormal Motor Proteins Cause Kartagener Syndrome An abnormal form of a motor protein called dynein causes Kartagener syndrome, a genetic disorder characterized by chronic sinus and lung infections. Biofilms form in the thick mucus that collects in the airways, and the resulting bacterial activities and inflammation damage tissues.

Affected men can produce sperm but are infertile. Some have become fathers after a doctor injects their sperm cells directly into eggs. Review FIGURE 4.21 and FIQURE 4.24, then explain how abnormal dynein could cause the observed effects.

Chapter 4, Problem 1DAA, Abnormal Motor Proteins Cause Kartagener Syndrome An abnormal form of a motor protein called dynein

FIGURE 4.24 Cross-section of the flagellum of a sperm cell from A a human male affected by Kartagener syndrome and B an unaffected male.

Expert Solution & Answer

Summary Introduction

To explain: How abnormal dynein could cause Kartagener syndrome and male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in dynein (a component of cilia) arms. This results in the abnormal morphology of sperm tails and bronchial cilia.

Explanation of Solution

Refer to Fig. 4.20, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in dynein arms causes Kartagener syndrome. Refer to Fig. 4.24, “Cross-section of a sperm cell from A. a human male affected by Kartagener syndrome and B. an unaffected male” in the textbook. The lack of dynein arms results in the abnormal morphology of sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because defected dynein would affect the movement of flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

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Answer 3

Textbook Question

Chapter 4, Problem 1DAA

Abnormal Motor Proteins Cause Kartagener Syndrome An abnormal form of a motor protein called dynein causes Kartagener syndrome, a genetic disorder characterized by chronic sinus and lung infections. Biofilms form in the thick mucus that collects in the airways, and the resulting bacterial activities and inflammation damage tissues.

Affected men can produce sperm but are infertile. Some have become fathers after a doctor injects their sperm cells directly into eggs. Review FIGURE 4.21 and FIQURE 4.24, then explain how abnormal dynein could cause the observed effects.

Chapter 4, Problem 1DAA, Abnormal Motor Proteins Cause Kartagener Syndrome An abnormal form of a motor protein called dynein

FIGURE 4.24 Cross-section of the flagellum of a sperm cell from A a human male affected by Kartagener syndrome and B an unaffected male.

Expert Solution & Answer

Summary Introduction

To explain: How abnormal dynein could cause Kartagener syndrome and male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in dynein (a component of cilia) arms. This results in the abnormal morphology of sperm tails and bronchial cilia.

Explanation of Solution

Refer to Fig. 4.20, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in dynein arms causes Kartagener syndrome. Refer to Fig. 4.24, “Cross-section of a sperm cell from A. a human male affected by Kartagener syndrome and B. an unaffected male” in the textbook. The lack of dynein arms results in the abnormal morphology of sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because defected dynein would affect the movement of flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

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Answer 4

Textbook Question

Chapter 4, Problem 1DAA

Abnormal Motor Proteins Cause Kartagener Syndrome An abnormal form of a motor protein called dynein causes Kartagener syndrome, a genetic disorder characterized by chronic sinus and lung infections. Biofilms form in the thick mucus that collects in the airways, and the resulting bacterial activities and inflammation damage tissues.

Affected men can produce sperm but are infertile. Some have become fathers after a doctor injects their sperm cells directly into eggs. Review FIGURE 4.21 and FIQURE 4.24, then explain how abnormal dynein could cause the observed effects.

Chapter 4, Problem 1DAA, Abnormal Motor Proteins Cause Kartagener Syndrome An abnormal form of a motor protein called dynein

FIGURE 4.24 Cross-section of the flagellum of a sperm cell from A a human male affected by Kartagener syndrome and B an unaffected male.

Expert Solution & Answer

Summary Introduction

To explain: How abnormal dynein could cause Kartagener syndrome and male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in dynein (a component of cilia) arms. This results in the abnormal morphology of sperm tails and bronchial cilia.

Explanation of Solution

Refer to Fig. 4.20, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in dynein arms causes Kartagener syndrome. Refer to Fig. 4.24, “Cross-section of a sperm cell from A. a human male affected by Kartagener syndrome and B. an unaffected male” in the textbook. The lack of dynein arms results in the abnormal morphology of sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because defected dynein would affect the movement of flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

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Answer 5

Textbook Question

Answer 6

Textbook Question

Answer 7

Expert Solution & Answer

Summary Introduction

To explain: How abnormal dynein could cause Kartagener syndrome and male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in dynein (a component of cilia) arms. This results in the abnormal morphology of sperm tails and bronchial cilia.

Explanation of Solution

Refer to Fig. 4.20, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in dynein arms causes Kartagener syndrome. Refer to Fig. 4.24, “Cross-section of a sperm cell from A. a human male affected by Kartagener syndrome and B. an unaffected male” in the textbook. The lack of dynein arms results in the abnormal morphology of sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because defected dynein would affect the movement of flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

Answer 8

Expert Solution & Answer

Summary Introduction

To explain: How abnormal dynein could cause Kartagener syndrome and male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in dynein (a component of cilia) arms. This results in the abnormal morphology of sperm tails and bronchial cilia.

Explanation of Solution

Refer to Fig. 4.20, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in dynein arms causes Kartagener syndrome. Refer to Fig. 4.24, “Cross-section of a sperm cell from A. a human male affected by Kartagener syndrome and B. an unaffected male” in the textbook. The lack of dynein arms results in the abnormal morphology of sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because defected dynein would affect the movement of flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Summary Introduction

To explain: How abnormal dynein could cause Kartagener syndrome and male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in dynein (a component of cilia) arms. This results in the abnormal morphology of sperm tails and bronchial cilia.

Answer 12

Explanation of Solution

Refer to Fig. 4.20, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in dynein arms causes Kartagener syndrome. Refer to Fig. 4.24, “Cross-section of a sperm cell from A. a human male affected by Kartagener syndrome and B. an unaffected male” in the textbook. The lack of dynein arms results in the abnormal morphology of sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because defected dynein would affect the movement of flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

Answer 13

Ch. 4 - Abnormal Motor Proteins Cause Kartagener Syndrome...Ch. 4 - All cells have these three things in common:...Ch. 4 - Prob. 2SQ Ch. 4 - Prob. 3SQ Ch. 4 - True or false? Some protists start out life with...Ch. 4 - Prob. 5SQ Ch. 4 - True or false? Ribosomes are only found in...Ch. 4 - Unlike eukaryotic cells, prokaryotic...Ch. 4 - Enzymes. contalned in _______ break down worn-out...Ch. 4 - Put the following structures in order according to...

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