The functional groups in these molecules and the basic difference between the the two structure are to be determined. Concept introduction: Simvastatin Formula: C 25 H 38 O 5 Pravastatin Formula: C 23 H 36 O 7 Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used in combination with diet, exercise, and weight loss for lowering cholesterol and preventing cardiovascular disease. Simvastatin, marketed under the trade name Zocor among others, is a lipid-lowering medication.

Question

You are trying to decide if there is a single reagent you can add that will make the following synthesis possible without any other major side products: xi 1. ☑ 2. H₂O хе i Draw the missing reagent X you think will make this synthesis work in the drawing area below. If there is no reagent that will make your desired product in good yield or without complications, just check the box under the drawing area and leave it blank. Click and drag to start drawing a structure. There is no reagent that will make this synthesis work without complications. : ☐ S ☐

Answer 1

Question

Chapter 3.SE, Problem 53AP

Interpretation Introduction

Interpretation:

The functional groups in these molecules and the basic difference between the the two structure are to be determined.

Concept introduction:

Simvastatin

Formula: C₂₅H₃₈O₅

Pravastatin

Formula: C₂₃H₃₆O₇

Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used in combination with diet, exercise, and weight loss for lowering cholesterol and preventing cardiovascular disease.

Simvastatin, marketed under the trade name Zocor among others, is a lipid-lowering medication.

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