
Concept explainers
To determine:
The sequence of immune response by B and T cells.
Introduction:
The white blood cells are a type of cells associated with immune system. They help body in fighting against the agents which may cause infections or other diseases. They are made in the bone marrow and found in blood and lymph. B and T lymphocytes are a type of white blood cells that help in removal of the pathogens from the body.

Explanation of Solution
In the antigen representing process, first the antigen is encountered by a macrophage and the macrophage digest the pathogen by breaking it into pieces. The processed antigen is then displayed on the surface of the macrophages and carries to the T cells. The macrophage binds to the helper T cells with the extramembrane receptors. This binding activated the T cells and this activated helper T cells attaches to the B cells and cytotoxic T cells. The B cells starts producing antibodies against this antigen and the cytotoxic t cells release cytokines to remove the pathogen.
Hnce, the correct sequence from top to bottom is: 2, 4, 1, 5, 3.
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