
To determine:
How does cyclosporine prevent rejection of transplanted organs.
Introduction:
Cyclosporine drugs are given to the patient who undergoes organ transplantation. Cyclosporine is responsible for the inhibition of cytokine secretion which stimulates helper T cell to divide and proliferate to induce an immune response against nonself cells.
To hypothesize:
A hypothesis to explain the phenomenon that why patients who received cyclosporine following transplants develop various kinds of cancers many years later.
Introduction:
To reduce the risk of organ transplant failure cyclosporine drugs are given to the patient who undergoes organ transplantation. It inhibits cytokine secretion which is responsible for the stimulation of immune response. But after many years these patients develop cancers.

Want to see the full answer?
Check out a sample textbook solution
Chapter 37 Solutions
Biology
- 22. Which of the following mutant proteins is expected to have a dominant negative effect when over- expressed in normal cells? a. mutant PI3-kinase that lacks the SH2 domain but retains the kinase function b. mutant Grb2 protein that cannot bind to RTK c. mutant RTK that lacks the extracellular domain d. mutant PDK that has the PH domain but lost the kinase function e. all of the abovearrow_forwardWhat is the label ?arrow_forwardCan you described the image? Can you explain the question as well their answer and how to get to an answer to an problem like this?arrow_forward
- Describe the principle of homeostasis.arrow_forwardExplain how the hormones of the glands listed below travel around the body to target organs and tissues : Pituitary gland Hypothalamus Thyroid Parathyroid Adrenal Pineal Pancreas(islets of langerhans) Gonads (testes and ovaries) Placentaarrow_forwardWhat are the functions of the hormones produced in the glands listed below: Pituitary gland Hypothalamus Thyroid Parathyroid Adrenal Pineal Pancreas(islets of langerhans) Gonads (testes and ovaries) Placentaarrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage LearningHuman Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage LearningBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
- Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning




