Propose the mechanism for the formation of polymeric resin by the reaction of polystyrene with n-(hydroxymethyl) pthalimide and triflouromethanesulphonic acid followed by the reaction with hydrazine. Concept introduction: In the Merrifield solid-phase method, peptide synthesis is carried out with the growing amino acid chain covalently bonded to small beads of a polymer resin, rather than in solution. S N 2 reaction is a type of reaction mechanism in which one bond is broken and one bond is formed simultaneously. In first step nucleophilic substitution reaction takes place. Since two reacting species are involved in the slow (rate-determining) step, this leads to the term substitution nucleophilic ( bi -molecular) or S N 2.

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Answer 1

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 31.SE, Problem 18MP

Interpretation Introduction

Interpretation:

Propose the mechanism for the formation of polymeric resin by the reaction of polystyrene with n-(hydroxymethyl) pthalimide and triflouromethanesulphonic acid followed by the reaction with hydrazine.

Concept introduction:

In the Merrifield solid-phase method, peptide synthesis is carried out with the growing amino acid chain covalently bonded to small beads of a polymer resin, rather than in solution.

S_N2 reaction is a type of reaction mechanism in which one bond is broken and one bond is formed simultaneously. In first step nucleophilic substitution reaction takes place. Since two reacting species are involved in the slow (rate-determining) step, this leads to the term substitution nucleophilic (bi-molecular) or S_N2.

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Answer 2

Question

Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 31.SE, Problem 18MP

Interpretation Introduction

Interpretation:

Propose the mechanism for the formation of polymeric resin by the reaction of polystyrene with n-(hydroxymethyl) pthalimide and triflouromethanesulphonic acid followed by the reaction with hydrazine.

Concept introduction:

In the Merrifield solid-phase method, peptide synthesis is carried out with the growing amino acid chain covalently bonded to small beads of a polymer resin, rather than in solution.

S_N2 reaction is a type of reaction mechanism in which one bond is broken and one bond is formed simultaneously. In first step nucleophilic substitution reaction takes place. Since two reacting species are involved in the slow (rate-determining) step, this leads to the term substitution nucleophilic (bi-molecular) or S_N2.

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Answer 3

Question

Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 31.SE, Problem 18MP

Interpretation Introduction

Interpretation:

Propose the mechanism for the formation of polymeric resin by the reaction of polystyrene with n-(hydroxymethyl) pthalimide and triflouromethanesulphonic acid followed by the reaction with hydrazine.

Concept introduction:

In the Merrifield solid-phase method, peptide synthesis is carried out with the growing amino acid chain covalently bonded to small beads of a polymer resin, rather than in solution.

S_N2 reaction is a type of reaction mechanism in which one bond is broken and one bond is formed simultaneously. In first step nucleophilic substitution reaction takes place. Since two reacting species are involved in the slow (rate-determining) step, this leads to the term substitution nucleophilic (bi-molecular) or S_N2.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 31.SE, Problem 18MP

Interpretation Introduction