INTEG. PRIN OF ZOO >LL< W/ CONNECT - FD
18th Edition
ISBN: 9781265230234
Author: HICKMAN
Publisher: MCG
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Chapter 31, Problem 1FFT
At high altitudes, the partial pressure of oxygen is lower. How might you expect this lower oxygen level to affect the ability of the blood to transport respiratory gases, and what would be the effect on respiring tissues?
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 31 Solutions
INTEG. PRIN OF ZOO >LL< W/ CONNECT - FD
Ch. 31 - Name the chief intracellular electrolytes and the...Ch. 31 - What is the fate of spent erythrocytes in the...Ch. 31 - Prob. 3RQCh. 31 - Two distinctly different styles of circulatory...Ch. 31 - Place the following in correct order to describe...Ch. 31 - Trace the flow of blood through a mammalian heart,...Ch. 31 - Explain the origin and conduction of the...Ch. 31 - Define the terms systole and diastole. Distinguish...Ch. 31 - Prob. 9RQCh. 31 - Prob. 10RQ
Ch. 31 - Prob. 11RQCh. 31 - Describe an advantage of a fishs gills for...Ch. 31 - Describe the tracheal system of insects. What is...Ch. 31 - Trace the route of inspired air in humans from the...Ch. 31 - Prob. 15RQCh. 31 - How does a frog ventilate its lungs? Contrast an...Ch. 31 - What is the role of carbon dioxide in the control...Ch. 31 - Prob. 18RQCh. 31 - Prob. 19RQCh. 31 - The ability of hemoglobin to bind oxygen decreases...Ch. 31 - At high altitudes, the partial pressure of oxygen...
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