Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 30, Problem 15TYK
Summary Introduction

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The use of growing genetic understanding that shows the link between the fungal and animal genome, to develop the new antifungal drugs. And the name of antifungal drugs that exploit the biochemical differences between animals and fungai.

Introduction:

Phylogenetic relationship between the plants, animals and fungi shows that fungai are more closely related to the animals compare to the plants. The comparison of ribosomal RNA sequences refined the studies based on genetic “Life of tree” pioneered by Carl Woese of the University of Illinois. The new findings mentioned in the journal Science indicates that protists which is a single cell creature, is the common ancestor of animals and fungi. The similarity in characteristic is like spending part of its early life cycle in a mobile and membranous form like a human sperm, and later growing a stiff cell wall similar to the fungi.

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You have been asked to consult for a biotech company that is seeking to understand why some fungi can live in very extreme environments, such as the high temperatures inside naturally occurring hot springs. The company has isolated two different fungal species, F. cattoriae and W. gravinius, both of which can grow at temperatures exceeding 95°C. The company has determined the following things about these fungal species (see attached image) By sequencing and examining their genomes, the biotech company hopes to understand why these species can live in extreme environments. However, the company only has the resources to sequence one genome, and would like your input as to which species should be sequenced and whether you believe a shotgun strategy will work in this case.
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