Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN: 9781285866932
Author: Lauralee Sherwood
Publisher: Cengage Learning
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Chapter 3, Problem 7RE
Summary Introduction
To match:
The description of cell junction on the left with the cell junction on the right.
Introduction:
In the tissues where the cells are present in proximity to each other, the cell-adhesion molecules provide certain tissue cohesion as they combine the nearby cells with each other. However, some of the cells within the given kinds of tissues are directly associated with each other via one of the three kinds of unique cell junctions, that is, the tight junctions, desmosomes, or the gap junctions.
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During a microscopy exercise in the anatomy laboratory,a student makes the following observations about a tissuesection: (1) The section contains some different types ofscattered protein fibers—that is, they exhibit differentwidths, some are branched, some are long and unbranched,and their staining characteristics differ (some are seenonly with specific stains). (2) Several cell types withdifferent morphologies are scattered throughout the section,but these cells are not grouped tightly together. (3) Theexamined section has some “open spaces”—that is, placesbetween cells and the observed fibers in the section thatappear clear with no recognizable features. What type oftissue is the student observing? Where might this tissue befound in the body?
Match the following to their proper description (answers may be used more than once).
Gap junctions
Adhering junctions
Desmosomes
Hemidesmosomes
Tight junctions
Tight junctions
Tight junctions
Connexons
Connexons
Zonulae adherens
Cadherins
Desmosomes
Are also known as “zonulae adherens”.
Are also known as “zonulae occludens”.
Are calcium ion-dependent glycoproteins that mediate adhesion in adhering junctions.
Are hexameric complexes formed by connexin proteins.
Bind the cells to the basal lamina.
Contain a central hydrophilic pore and occur in gap junctions.
Contain protein filaments.
Encircle the cell and provide firm connections with neighboring cells.
Form seals that prevent the flow materials between adjacent epithelial cells.
Form thin bands that completely encircle the cell.
Permit the rapid exchange of materials between adjacent cells.
Provide firm adhesion between cells via protein filaments that are coupled to intracellular filaments via a protein plaques.
Which of the following statements related to intercellular junctions is false?
Cadherins are important cell-cell adhesion proteins. A cadherin-mediated junction involves many cadherin
molecules to achieve strong adhesion.
The cytoplasmic domain of cadherins interacts with actin or intermediate filament cytoskeleton through
adaptor proteins.
Because tight junctions seal the membrane of adjacent epithelial cells, transmembrane proteins in the apical
portion of the plasma membrane cannot move to the basal lateral domain or vice versa.
Proteins can diffuse through an open gap junction.
Chapter 3 Solutions
Human Physiology: From Cells to Systems (MindTap Course List)
Ch. 3.1 - Draw how phospholipid molecules align themselves...Ch. 3.1 - Prob. 2CYUCh. 3.1 - Prob. 3CYUCh. 3.2 - Prob. 1CYUCh. 3.2 - Prob. 2CYUCh. 3.2 - Prob. 3CYUCh. 3.3 - Prob. 1CYUCh. 3.3 - Distinguish between passive and active forces that...Ch. 3.4 - List the means of unassisted membrane transport.Ch. 3.4 - Prob. 2CYU
Ch. 3.4 - Prob. 3CYUCh. 3.5 - Draw a graph comparing simple diffusion down a...Ch. 3.5 - Describe what causes the carrier to change shape...Ch. 3.5 - Distinguish between symport and antiport.Ch. 3.6 - Prob. 1CYUCh. 3.6 - Describe the relative contributions of k+ and Na+...Ch. 3.6 - Prob. 3CYUCh. 3 - The nonpolar tails of the phospholipid molecules...Ch. 3 - Prob. 2RECh. 3 - Prob. 3RECh. 3 - At resting membrane potential, there is a slight...Ch. 3 - Using the answer code on the right, indicate which...Ch. 3 - Prob. 6RECh. 3 - Prob. 7RECh. 3 - Prob. 1UCCh. 3 - Prob. 2UCCh. 3 - What two properties of a particle influence...Ch. 3 - Prob. 4UCCh. 3 - Prob. 5UCCh. 3 - Prob. 6UCCh. 3 - Describe the contribution of each of the following...Ch. 3 - Using the Nernst equation, calculate the...Ch. 3 - One of the important uses of the Nernst equation...Ch. 3 - Using the Goldman-Hodgkin-Katz equation, determine...Ch. 3 - When William H. was helping victims after a...Ch. 3 - Which of the following methods of transport is...Ch. 3 - Assume that a membrane permeable to Na+ but not to...Ch. 3 - A solution may have the same osmolarity as normal...Ch. 3 - Prob. 4TAHLCh. 3 - Prob. 5TAHL
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- Which of the following cell junctions is involved with anchoring the extracIular matrix to the cell? (LO-K8) I-Adherens junctions II-Desmosomes III-Hemidesmosomes IV-Gap junctions I, II, III, and IV III and IV I and III I, II and IIIarrow_forwardMost cells are linked together forming a tissue and membrane junctions are important factors in this phenomenon. Compare and contrast the structure and function of a tight junction versus a desmosome versus a gap junction.arrow_forwardMany proteins are involved in contributing to the adhesive properties of the major cell-cell attachments. Can you match the correct family of proteins with the type of cell-cel they are associated with? Drag the proteins to match with the attachment types. Terms can be used more than once. Reset Help Integrins Gap junctions Cadherins = Adherens junctions Connexins Tight junctions %3D Claudins = Desmosomes = Hemidesmosomes Submit Request Answerarrow_forward
- In the cell there are three types of filaments that form the cell skeleton. Answer:a)Which they are.b)How they are constructed.c)What their function is.arrow_forwardSecretory vesicles fuse with the cell membrane to release their contents to the outside of the cell. In this process, the membrane of the secretory vesicle becomes part of the cell membrane. Because small pieces of membrane are continually added to the cell membrane, we would expect the cell membrane to become larger and larger as secretion continues. However, the cell membrane stays the same size. Explain how this happens.arrow_forwardIn a monolayer of cultured epithelial cells, the cells may or may not have formed tight junctions. What experimental test could be used to determine it the cells have functional tight junction structures? Place a small dye (1 k Da in molecular weight) into the culture media of cells cultured on a glass coverslip and use live imaging to monitor whether the dye can penetrate into the O cytoplasm of the cells, as would be expected if the cells have functional tight junctions. Inject a cell with a small dye (<1 kDa in molecular weight) and use live cell imaging to track whether the dye moves into neighboring cells, as would be expected if the cells have functional O tight junctions.arrow_forward
- Make an illustration/representation that will show how cell membrane carry out function of Selectively Permeable. Explain the function too. Please make the illustration/representation readable and please add labels.arrow_forwardSelect the best answer or answers from the choices given: Membrane junctions that allow nutrients or ions to flow from cell to cell are (a) desmosomes, (b) gap junctions, (c) tight junctions, (d) all of these.arrow_forwardWhich of the followings is not true about the function of the Tight Junctions? (LO- K8) They hold the cells together They act as a barrier They help maintain cell polarity They prevent lateral diffusion of proteins, ions, molecules They play an important role in maintaining the blood brain barrier They connect the adjacent cells intercellularly to the intermediate cytoskeletal filamentsarrow_forward
- Describe the shape of transporting cells observed. Was it simple or stratified? Are the junctions between cells tight or leaky? Why does this histology support their function?arrow_forwardBriefly summarize the study and the defects of cell junctions or the extracellular matrix that leads to symptoms, a condition or disease. Make sure to describe what the actual defect is at the cellular or molecular level as far as it is known and what the consequences are for patients. add referencearrow_forwardLook carefully at the transmembrane proteins shown in Figure 11–29. What can you say about their mobility in the membrane?arrow_forward
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