ORGANIC CHEMISTRY-PRINT (LL)-W/WILEY
4th Edition
ISBN: 9781119761105
Author: Klein
Publisher: WILEY
expand_more
expand_more
format_list_bulleted
Question
Chapter 3, Problem 74IP
Interpretation Introduction
Interpretation:
Most acidic protons needed to be found in the given anti-viral drug rilpivirine.
Concept introduction:
Acidic strength of the molecule depends on the stability of the Conjugate anion.
- If the conjugate anion is more resonance stabilized, the acid considered as strong acid, the anion is weak base and the removed proton considered as a strong acidic proton.
- If the negative charge present in the structure is more delocalized and stabilized by more number of atoms (electronegative), then the corresponding proton considered as more acidic proton.
To give: the two most acidic protons in the antiviral drug, and give the most acidic between them.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Problem 6-29
Identify the functional groups in the following molecules, and show the polarity of each:
(a)
CH3CH2C=N
CH, CH, COCH
(c)
CH3CCH2COCH3
NH2
(e)
OCH3
(b)
(d) O
Problem 6-30
Identify the following reactions as additions, eliminations, substitutions, or rearrangements:
(a) CH3CH2Br
+ NaCN
CH3CH2CN ( + NaBr)
Acid
-OH
(+ H2O)
catalyst
(b)
+
(c)
Heat
NO2
Light
+
02N-NO2
(+ HNO2)
(d)
Predict the organic product of Y that is formed in the reaction below, and draw the skeletal ("line") structures of the missing organic product. Please include all steps & drawings & explanations.
Please choose the best reagents to complete the following reaction
Chapter 3 Solutions
ORGANIC CHEMISTRY-PRINT (LL)-W/WILEY
Ch. 3.2 - Prob. 1LTSCh. 3.2 - Prob. 1PTSCh. 3.3 - Prob. 2LTSCh. 3.3 - Prob. 4PTSCh. 3.3 - Prob. 5ATSCh. 3.3 - Prob. 6ATSCh. 3.3 - Prob. 3LTSCh. 3.3 - Prob. 7PTSCh. 3.4 - Prob. 5LTSCh. 3.4 - Prob. 13PTS
Ch. 3.4 - Prob. 6LTSCh. 3.4 - Prob. 15PTSCh. 3.4 - Prob. 16ATSCh. 3.4 - Prob. 17ATSCh. 3.4 - Prob. 7LTSCh. 3.4 - Prob. 18PTSCh. 3.4 - Prob. 19PTSCh. 3.4 - Prob. 8LTSCh. 3.4 - Prob. 23PTSCh. 3.4 - Prob. 24PTSCh. 3.4 - Prob. 25ATSCh. 3.4 - Prob. 26ATSCh. 3.10 - Prob. 13LTSCh. 3 - Prob. 37PPCh. 3 - Prob. 38PPCh. 3 - Prob. 39PPCh. 3 - Prob. 40PPCh. 3 - Prob. 41PPCh. 3 - Prob. 42PPCh. 3 - Prob. 44PPCh. 3 - Prob. 45PPCh. 3 - Prob. 46PPCh. 3 - Prob. 47PPCh. 3 - Prob. 48PPCh. 3 - Prob. 49PPCh. 3 - Prob. 50PPCh. 3 - Prob. 51PPCh. 3 - Prob. 52PPCh. 3 - Prob. 64IPCh. 3 - Prob. 66IPCh. 3 - Prob. 67IPCh. 3 - Prob. 71IPCh. 3 - Prob. 72IPCh. 3 - Prob. 73IPCh. 3 - Prob. 74IPCh. 3 - Prob. 75IPCh. 3 - Prob. 76IP
Knowledge Booster
Similar questions
- Problem 6-17 Look at the following energy diagram: Energy Reaction progress (a) Is AG for the reaction positive or negative? Label it on the diagram. (b) How many steps are involved in the reaction? (c) How many transition states are there? Label them on the diagram. Problem 6-19 What is the difference between a transition state and an intermediate? Problem 6-21 Draw an energy diagram for a two-step reaction with Keq > 1. Label the overall AG°, transition states, and intermediate. Is AG° positive or negative? Problem 6-23 Draw an energy diagram for a reaction with Keq = 1. What is the value of AG° in this reaction?arrow_forwardProblem 6-37 Draw the different monochlorinated constitutional isomers you would obtain by the radical chlorination of the following compounds. (b) (c) Problem 6-39 Show the structure of the carbocation that would result when each of the following alkenes reacts with an acid, H+. (a) (b) (c)arrow_forwardPlease draw the major product of this reaction. Ignore inorganic byproducts and the carboxylic side productarrow_forward
- predict the product formed by the reaction of one mole each of cyclohex-2-en-1-one and lithium diethylcuprate. Assume a hydrolysis step follows the additionarrow_forwardPlease handwriting for questions 1 and 3arrow_forwardIs (CH3)3NHBr an acidic or basic salt? What happens when dissolved in aqueous solution? Doesn't it lose a Br-? Does it interact with the water? Please advise.arrow_forward
- © Macmilla Finish resonance structure 3 Select Draw Templates More C H N 0 H H S Erase Which structure is the most stable (lowest energy) resonance contributor? The structure with the positive charge on nitrogen and negative charges on oxygen and sulfur. All structures are equal in stability. The structure with the positive charge on nitrogen and negative charges on sulfur and carbon. The structure with the positive charge on nitrogen and negative charges on oxygen and carbon. Q2Qarrow_forwardThree pure compounds are formed when 1.00 g samples of element x combine with, respectively, 0.472 g, 0.630 g, and 0.789 g of element z. The first compound has the formula x2Z3. find the empricial formula of the other two compoundsarrow_forwardDraw the product and the mechanism A. excess H*; 人 OH H*; B. C. D. excess OH ✓ OH H*; H₂O 1. LDA 2. H*arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
ChemistryChemistryISBN:9781305957404Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCostePublisher:Cengage Learning
ChemistryChemistryISBN:9781259911156Author:Raymond Chang Dr., Jason Overby ProfessorPublisher:McGraw-Hill Education
Principles of Instrumental AnalysisChemistryISBN:9781305577213Author:Douglas A. Skoog, F. James Holler, Stanley R. CrouchPublisher:Cengage Learning
Organic ChemistryChemistryISBN:9780078021558Author:Janice Gorzynski Smith Dr.Publisher:McGraw-Hill Education
Chemistry: Principles and ReactionsChemistryISBN:9781305079373Author:William L. Masterton, Cecile N. HurleyPublisher:Cengage Learning
Elementary Principles of Chemical Processes, Bind...ChemistryISBN:9781118431221Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. BullardPublisher:WILEY
Chemistry
Chemistry
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Cengage Learning
Chemistry
Chemistry
ISBN:9781259911156
Author:Raymond Chang Dr., Jason Overby Professor
Publisher:McGraw-Hill Education
Principles of Instrumental Analysis
Chemistry
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Cengage Learning
Organic Chemistry
Chemistry
ISBN:9780078021558
Author:Janice Gorzynski Smith Dr.
Publisher:McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry
ISBN:9781305079373
Author:William L. Masterton, Cecile N. Hurley
Publisher:Cengage Learning
Elementary Principles of Chemical Processes, Bind...
Chemistry
ISBN:9781118431221
Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:WILEY