ORGANIC CHEM W/BIOLOGICAL TOP. ACCESS
6th Edition
ISBN: 9781264382545
Author: SMITH
Publisher: MCG CUSTOM
expand_more
expand_more
format_list_bulleted
Question
Chapter 3, Problem 56P
Interpretation Introduction
(a)
Interpretation: The product of the reaction of acebutolol with HCl is to be drawn.
Concept introduction: The most basic
Interpretation Introduction
(b)
Interpretation: The solubility of acebutolol and its hydrochloride salt in water is to be discussed.
Concept introduction: The solubility of a compound depends on its interactions with the solvent molecule.
Interpretation Introduction
(c)
Interpretation: The reason as to why acebutolol is marketed as a hydrochloride salt rather than a neutral molecule is to be stated.
Concept introduction: The drug having more solubility is marketed for its maximum utilization.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Many drugs are sold as their hydrochloride salts (R,NH2* CI), formed by reaction of an amine (R,NH) with HCI.
он
acebutolol
a. Draw the product (a hydrochloride salt) formed by reaction of acebutolol with HCI. Acebutolol is a ß blocker used to treat
high blood pressure.
b. Discuss the solubility of acebutolol and its hydrochloride salt in water.
c. Offer a reason as to why the drug is marketed as a hydrochloride salt rather than a neutral amine.
27. Put a small amount of soap in a test tube and mix the soap well with water. Tap a few drops of
the solution on both red and blue litmus paper. You observed that the red litmus paper turned
blue and the blue litmus paper did not change. Based on these observations, which of the
following is true?
(2 Puan)
Soap is basic
Soap is acidic
Soap is neutral
Sugar will dissolve most quickly if the solution is
1. allowed to sit
2. stirred rapidly
3. stirred slowly
4. chilled before stirring
O 2
4
Chapter 3 Solutions
ORGANIC CHEM W/BIOLOGICAL TOP. ACCESS
Ch. 3.1 - Prob. 1PCh. 3.2 - (a) Classify the carbon atoms in each compound as...Ch. 3.2 - Problem 3.3 Classify a carbon atom by the number...Ch. 3.2 - Classify each alkyl halide and alcohol as , or...Ch. 3.2 - Prob. 5PCh. 3.2 - Prob. 6PCh. 3.2 - Draw the structure of a compound of molecular...Ch. 3.2 - Prob. 8PCh. 3.2 - Prob. 9PCh. 3.2 - Draw the structure of a compound fitting each...
Ch. 3.4 - Predict which compound in each pair has the higher...Ch. 3.4 - Prob. 17PCh. 3.4 - a Label the hydrophobic and hydrophilic portions...Ch. 3.5 - Prob. 21PCh. 3 - 3.29
Identify the functional groups in the...Ch. 3 - Prob. 32PCh. 3 - 3.31 For each alkane: (a) classify each carbon...Ch. 3 - 3.32 Identify the functional groups in each...Ch. 3 - 3.33 Identify each functional group located in the...Ch. 3 - 3.34 (a)Identify the functional groups in...Ch. 3 - Draw seven constitutional isomers with molecular...Ch. 3 - Prob. 38PCh. 3 - Prob. 39PCh. 3 - Prob. 40PCh. 3 - Intramolecular force of attraction are often...Ch. 3 - 3.40 (a) Draw four compounds with molecular...Ch. 3 - 3.41 Rank the compounds in each group in order of...Ch. 3 - Explain why CH3CH2NHCH3 has higher boiling point...Ch. 3 - Prob. 45PCh. 3 - 3.44 Rank the following compounds in order of...Ch. 3 - Prob. 47PCh. 3 - 3.50 Predict the solubility of each of the...Ch. 3 - Prob. 52PCh. 3 - Prob. 53PCh. 3 - 3.53 THC is the active component in marijuana, and...Ch. 3 - Prob. 55PCh. 3 - Prob. 56PCh. 3 - 3.60 Quinapril (trade name Accupril) is a drug...Ch. 3 - 3.61 Answer each question about oxycodone, a...Ch. 3 - Prob. 65PCh. 3 - Prob. 66PCh. 3 - 3.64 Explain why A is less water soluble than B,...Ch. 3 - 3.65 Recall from section 1.10B that there is...
Knowledge Booster
Similar questions
- 5. Sodium acetate and sodium propionate are poor soaps. Why?arrow_forward2. Consider a glycolic acid (HOCH,COOH) and glycolate (HOCH,Co0) buffer system. Write the chemical equation representing a. The glycolic acid-glycolate equilibrium b. The buffer system titrated (added) with a strong base C. The buffer system titrated (added) with a strong acidarrow_forward7. Which of the following are soluble in water? a. CH3CH2CH2OH b. CH3CH2CH₂OCH2CH3 C. CH3CH2CH2CH3 d. CH3CH2CH2CH2COOHarrow_forward
- which organic compound dissolves in water? 1. 2-pentanol 2.1-hexanol 3. diethylether 4. 3-methyl-3-pentanol which organic compound dissolves in 10% NaOH? 1. 2-pentanol 2. 1-hexanol 3. diethylether 4. 3-methyl-3-pentanolarrow_forwardPlease answer question number 3arrow_forwardCalculate the amount of ascorbic acid in each sample. Each mL of 0.1 N iodine is equivalent to 8.806 mg of C6H8O6arrow_forward
- Which of the following are first aid measures for glacial acetic acid? Select one: a. If swallowed, rinse mouth with water (unless the affected person is unconscious). Consult a physician. b. If in contact with the eyes, flush eyes with water for 15 minutes. Consult a physician and continue to wash eyes with water during transport to the hospital. c. If in contact with the skin, remove contaminated clothing and wash affected area with soap and water for at least 15 minutes. Consult a physician. d. All options are correct. e. If inhaled, move the affected person to fresh air and give artificial respiration if they are not breathing. Consult a physician.arrow_forwardTrue or False: Carboxylic acids containing six or more carbon atoms per molecule are more soluble in 3 M sodiumaqueous hydroxide than in dichloromethane.arrow_forwardTo determine the concentrations of caffeine in both red bull and coca-cola beverages, what is required?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Chemical Principles in the LaboratoryChemistryISBN:9781305264434Author:Emil Slowinski, Wayne C. Wolsey, Robert RossiPublisher:Brooks Cole
Chemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage Learning
Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage Learning
Chemistry: Matter and ChangeChemistryISBN:9780078746376Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl WistromPublisher:Glencoe/McGraw-Hill School Pub Co
EBK A SMALL SCALE APPROACH TO ORGANIC LChemistryISBN:9781305446021Author:LampmanPublisher:CENGAGE LEARNING - CONSIGNMENT
Chemical Principles in the Laboratory
Chemistry
ISBN:9781305264434
Author:Emil Slowinski, Wayne C. Wolsey, Robert Rossi
Publisher:Brooks Cole
Chemistry for Today: General, Organic, and Bioche...
Chemistry
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Cengage Learning
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Cengage Learning
Chemistry: Matter and Change
Chemistry
ISBN:9780078746376
Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Publisher:Glencoe/McGraw-Hill School Pub Co
EBK A SMALL SCALE APPROACH TO ORGANIC L
Chemistry
ISBN:9781305446021
Author:Lampman
Publisher:CENGAGE LEARNING - CONSIGNMENT