ORGANIC CHEM W/BIOLOGICAL TOP. ACCESS
ORGANIC CHEM W/BIOLOGICAL TOP. ACCESS
6th Edition
ISBN: 9781264382545
Author: SMITH
Publisher: MCG CUSTOM
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Chapter 3.2, Problem 8P
Interpretation Introduction

Interpretation: The primary, secondary or tertiary amides in dolastatin are to be classified.

Concept introduction: Amides are the acid derivatives in which a nitrogen atom is bonded to an adjacent carbonyl carbon. They are synthesized by the reaction of an acid chloride with an amine. Amides are produced when esters react with amines and ammonia. They are classified as primary, secondary or tertiary on the basis of the number of carbon atoms bonded to nitrogen atom.

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