Essentials of Human Anatomy & Physiology Laboratory Manual (7th Edition)
Essentials of Human Anatomy & Physiology Laboratory Manual (7th Edition)
7th Edition
ISBN: 9780134424835
Author: Elaine N. Marieb, Pamela B. Jackson
Publisher: PEARSON
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Chapter 3, Problem 36CT

Two examples of chemotherapeutic drugs (used to treat cancer) and their cellular actions are given below. Explain why each drug could be fatal to a cell.

• Vincristine: damages the mitotic spindle.

• Doxorubicin: binds to DNA and blocks messenger RNA synthesis.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.

Chapter 3 Solutions

Essentials of Human Anatomy & Physiology Laboratory Manual (7th Edition)

Ch. 3 - Which of the following terms describe cardiac...Ch. 3 - Cancer is the same as a. all tumors. b. al...Ch. 3 - Prob. 13SAECh. 3 - 14. Although cells have differences that reflect...Ch. 3 - Describe the special function of DNA found in the...Ch. 3 - 16. Describe the four structural components of the...Ch. 3 - Prob. 17SAECh. 3 - 18. What two structural characteristics of cell...Ch. 3 - Explain the effect of the following solutions on...Ch. 3 - Prob. 20SAECh. 3 - Define mitosis. Why is mitosis important?Ch. 3 - Prob. 22SAECh. 3 - Prob. 23SAECh. 3 - 24. Why can an organ be permanently damaged if its...Ch. 3 - Describe the relative roles of DNA and RNA in...Ch. 3 - Define tissue. List the four major types of...Ch. 3 - Describe the general characteristics of epithelial...Ch. 3 - 28. Where is ciliated epithelium found, and what...Ch. 3 - What are the general structural characteristics of...Ch. 3 - Name a connective tissue with (1) a soft fluid...Ch. 3 - Prob. 31SAECh. 3 - 32. Tell where each of the three types of muscle...Ch. 3 - 33. How does tissue healing by fibrosis differ...Ch. 3 - Prob. 34SAECh. 3 - Prob. 35SAECh. 3 - Two examples of chemotherapeutic drugs (used to...Ch. 3 - Hydrocortisone is an anti-inflammatory drug that...Ch. 3 - John has severely injured his knee during football...Ch. 3 - 39. Three patients in an intensive care unit are...Ch. 3 - 40. Michael had a nervous habit of chewing on the...Ch. 3 - 41. Think carefully about the chemistry of the...Ch. 3 - 42. Jeanie was taken to the ER for heat stroke and...
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