Chapter 3, Problem 3.18P

The following data have been obtained for the effect of solvent composition on the solubility of a serine, an amino acid, at lO.O’C:

Volume % Methanol	0	10	20	30	40	60	80	100
Solubility (g/100 mL solvent)	22.72	18.98	11.58	6.415	4.205	1.805	0.85	0.65
Solution Density (g/rnL)	1.00	0.98	0.97	0.95	0.94	0.91	0.88	0.79

The data were obtained by mixing known volumes of methanol and water to obtain the desired solvent compositions, and then slowly adding measured amounts of serine to each mixture until no more would go into solution. The temperature was held constant at 10.0°C.

1. Derive an expression for solvent composition expressed as mass fraction of methanol, x, as a function of volume fraction of methanol, f.
2. Prepare a table of solubility of serine (g serine/g solution) versus mass fraction of methanol.