EBK PRINCIPLES OF HUMAN PHYSIOLOGY
EBK PRINCIPLES OF HUMAN PHYSIOLOGY
6th Edition
ISBN: 9780134399485
Author: STANFIELD
Publisher: PEARSON CO
bartleby

Concept explainers

bartleby

Videos

Textbook Question
Book Icon
Chapter 3, Problem 28E

As you know, fatty acids can be oxidized to provide energy for making ATP. This process begins with a set of reactions known as the fatty acid oxidation cycle, or beta oxidation. Before entering the cycle, a fatty acid reacts with coenzyme A to form a molecule called fatty acyl CoA. This molecule then enters the cycle and continues to go through it until all its carbons have been eliminated, as shown on the following page. From your examination of this diagram, answer the following questions for a 1 2-carbon fatty acid.

  1. How many acetyl CoA molecules will be produced by beta oxidation of this fatty acid? How many ATP molecules can be produced from each acetyl CoA molecule that goes through the Krebs cycle and oxidative phosphorylation?
  2. How many NAD+ and FAD molecules will be reduced? (Hint: How many bonds must be broken to split a 12-carbon fatty acid into acetyl CoA molecules?)
  3. How many ATP molecules will be produced per each NADH + H+ and each FADH2 molecule that provides electrons to the electron transport system?
  4. It takes two ATP molecules to get the cycle started. Based on this information and your answers to the previous questions, how many ATP molecules can be generated from a 1 2-carbon fatty acid?
  5. Chapter 3, Problem 28E, As you know, fatty acids can be oxidized to provide energy for making ATP. This process begins with

Blurred answer
Students have asked these similar questions
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine: (a) k, C0, V, and AUC* for the bolus iv data  (b) k, ka, B1, and AUC* for the po data  (c) k, ka, B1, and AUC* for the ip data  (d) relative bioavailability for po vs ip, Fpo/Fip  (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip    MAKE SURE ANSWERS HAVE UNITS if appropriate. SHOW ALL WORK, including equation used, variables used and each step to your solution.
2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0  Note that a µCi is a measure of the amount of radioactivity and hence is a measure of the amount of drug present.  Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this…
The current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?
Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Concepts of Biology
Biology
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:OpenStax College
Text book image
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Text book image
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Text book image
BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)
Biology
ISBN:9781305967359
Author:STARR
Publisher:CENGAGE L
Text book image
Body Structures & Functions
Biology
ISBN:9781285695495
Author:Scott
Publisher:Cengage
Text book image
Body Structures & Functions Updated
Biology
ISBN:9780357191606
Author:Scott
Publisher:Cengage
Anaerobic Respiration; Author: Bozeman Science;https://www.youtube.com/watch?v=cDC29iBxb3w;License: Standard YouTube License, CC-BY