BIOCHEMISTRY
BIOCHEMISTRY
8th Edition
ISBN: 9781319296186
Author: BERG
Publisher: MAC HIGHER
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Chapter 3, Problem 26P
Interpretation Introduction

Interpretation:

Two methods that could be applied to the study of hydrogen-deuterium exchange rates in proteins should be mentioned and explained.

Concept introduction:

Hydrogen-deuterium exchange is a reaction by which a covalently bonded hydrogen atoms are replaced by deuterium atoms. This method is commonly used for the solvent accessibility of proteins and thereby determining the tertiary structure of the protein. The protons on amide groups are exchangeable.

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