(a)
Interpretation:
The digestion of octapeptide AVGWRVKS with trypsin. The most suitable method for separation of the products between ion-exchange or gel-filtration chromatography should be determined.
Concept introduction:
A peptide bond is present between the two amino acids in a protein. During the formation of a peptide bond, a molecule of water is released. The amino group of an amino acid gets associated with the carboxyl group of another. Polypeptides and proteins are the chains formed by the amino acids.
(b)
Interpretation:
If the protein was digested with chymotrypsin. The optimal separation method should be explained.
Concept introduction:
A peptide bond is present between the two amino acids in a protein. During the formation of a peptide bond, a molecule of water is released. The amino group of an amino acid gets associated with the carboxyl group of another. Polypeptides and proteins are the chains formed by the amino acids.

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Chapter 3 Solutions
BIOCHEMISTRY
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- 2. Which one is the major organic product obtained from the following reaction? NaOH, H₂O heat A B C D Earrow_forwardCH3CH2CHO + propanal PhCH2CHO 2-phenylacetaldehyde mixture of four products NaOH 10. In the crossed aldol reaction of propanal and 2-phenylacetaldehyde shown above, a mixture of four products will be formed. Which ONE of the compounds below will NOT be formed in this crossed aldol reaction? OH Ph A H OH OH Ph H B OH OH H H H Ph Ph C Ph D Earrow_forwardAn organic chemist ordered the wrong item. She wanted to obtain 1-hydroxy-2-butanone, butinstead ordered 2-hydroxybutyraldehyde. As a good biochemist, show how the organic chemistcould use biological catalysis to make her desired compound.arrow_forward
- Predict the products of aldolase catalyzing the reaction with acetone and (S)-3-hydroxybutyraldehyde.arrow_forwardA cancer patient undergoing chemotherapy is taking a protein kinase inhibitor drug. The patientis an avid marathon runner and does not want to miss his upcoming race. Is it a good idea forthis patient to attempt a marathon while on this medication? Explain why or why not.arrow_forwardShow the fate of the hydrogen on carbon-2 of glucose.arrow_forward
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