Biology Today and Tomorrow without Physiology (MindTap Course List)
5th Edition
ISBN: 9781305117396
Author: Cecie Starr, Christine Evers, Lisa Starr
Publisher: Cengage Learning
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Chapter 3, Problem 1DID
Organelles and Cystic Fibrosis
A plasma membrane transport protein called CFTR moves chloride ions out of cells lining cavities and ducts of the lungs, liver, pancreas, intestines, and reproductive system. Water that follows the ions creates a thin film that allows mucus to slide easily through these structures.
People with cystic fibrosis (CF) have too few copies of the CFTR protein in the plasma membranes of their cells. Not enough chloride ions leave the cells, and so not enough water leaves them either. The result is thick, dry mucus that clogs the airways to the lungs and other passages. Symptoms include difficulty breathing and chronic lung infections. In 2000, researchers tracked the cellular location of the CFTR protein as it was being produced in cells from people with CF (Figure 3.13).
Figure 3.13 Cellular location of the CFTR protein.
Graph compares the amounts of CFTR protein found in endoplasmic reticulum, vesicles travel in g from ER to Golgi, and Golgi bodies in CF cells and normal cells.
Which organelle contains the least amount of CFTR protein in normal cells? In CF cells?
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Chapter 3 Solutions
Biology Today and Tomorrow without Physiology (MindTap Course List)
Ch. 3 - Prob. 1FIOCh. 3 - Organelles and Cystic Fibrosis A plasma membrane...Ch. 3 - Organelles and Cystic Fibrosis A plasma membrane...Ch. 3 - Prob. 3DIDCh. 3 - All cells have these three things in common: a....Ch. 3 - Unlike eukaryotic cells, prokaryotic cells...Ch. 3 - Every cell is descended from another cell. This...Ch. 3 - Prob. 4SQCh. 3 - True or false? Some protists start out life with...Ch. 3 - Cell membranes consist mainly of ________ and...
Ch. 3 - Prob. 7SQCh. 3 - In a lipid bilayer, the of all the lipid molecules...Ch. 3 - The main function of the endomembrane system is...Ch. 3 - Enzymes contained in __________ break down...Ch. 3 - Put the following structures in order according to...Ch. 3 - No animal cell has a ______. a. plasma membrane b....Ch. 3 - Prob. 13SQCh. 3 - Prob. 14SQCh. 3 - Match each cell component with its main function.Ch. 3 - In a classic episode of Star Trek, a gigantic...Ch. 3 - Prob. 2CTCh. 3 - What type of micrograph is shown below? Is the...
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